The pathology of Johne''s disease in sheep   总被引：4，自引：0，他引：4  

MJ CARRIGAN  JT SEAMAN 《Australian veterinary journal》1990,67(2):47-50

The clinical, gross and histopathological findings in 50 sheep affected with Johne's disease are described. Clinically 90% were emaciated and 20% showed severe diarrhoea. On necropsy there was thickening of the walls of the intestines, particularly of the ileum, caecum and less frequently the jejunum, but in 36% of sheep the changes were only mild. Histologically there was a granulomatous enteritis, typhlitis and colitis, with the most severe changes in the terminal ileum. High numbers of acid-fast organisms were present in the terminal ileum in over 70% of sheep. Mycobacterium paratuberculosis was cultured from only 8% of the sheep examined.  相似文献   

Haemorrhagic septicaemia in pigs     

JT MACKIE 《Australian veterinary journal》1996,74(5):399-400

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Effects of short-term light to heavy exercise on gastric ulcer development in horses and efficacy of omeprazole paste in preventing gastric ulceration     

White G  McClure SR  Sifferman R  Holste JE  Fleishman C  Murray MJ  Cramer LG 《Journal of the American Veterinary Medical Association》2007,230(11):1680-1682

OBJECTIVE: To determine the effects of 8 days of light to heavy exercise on gastric ulcer development in horses and determine the efficacy of omeprazole paste in preventing gastric ulceration. DESIGN: Randomized, controlled, multicenter clinical trial. ANIMALS: 102 horses with normal-appearing gastric mucosa on endoscopic examination that were in light to heavy training. PROCEDURES: Horses at 4 trial locations were allocated into replicates and sham dosed orally (empty syringe) or treated with a paste formulation of omeprazole (1 mg/kg [0.45 mg/ lb], PO) once daily for 8 days. Training regimens varied among locations and included early training for western performance events; walking, trotting, and cantering in a mechanical exerciser; and race training (2 locations). Prevalences of gastric ulceration at the completion of the 8-day treatment period were compared between groups. RESULTS: At the end of the 8-day treatment period, the proportion of omeprazole-treated horses free from gastric ulceration (88%) was significantly higher than the proportion of sham-dosed horses free from gastric ulceration (27%). CONCLUSIONS AND CLINICAL RELEVANCE: Results showed that horses in light to heavy training for as short as 8 days were at risk of developing gastric ulcers and that administration of omeprazole paste decreased the incidence of gastric ulcers.  相似文献   

Self-incompatibility: a self-recognition system in plants   总被引：18，自引：0，他引：18  

V Haring  J E Gray  B A McClure  M A Anderson  A E Clarke 《Science (New York, N.Y.)》1990,250(4983):937-941

Self-incompatibility (SI), a genetically controlled mechanism to prevent inbreeding in plants, offers a relatively simple model system for studying the interactions between plant cells or between a plant cell and the secreted product or products of another cell. Examples of two major types of SI, gametophytic and sporophytic, have been studied by cloning cDNAs corresponding to glycoproteins of the female tissues that segregate with particular variants encoded by the putative S locus. These secreted glycoproteins are envisaged to interact with the currently undescribed pollen component to cause arrest of pollen tube growth.  相似文献   

Recovery of Western Equine Encephalomyelitis Virus From Wild Bird Mites (Liponyssus sylviarum) in Kern County,California     

Reeves WC  Hammon WM  Furman DP  McClure HE  Brookman B 《Science (New York, N.Y.)》1947,105(2729):411-412

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Self-Assembled Smectic Phases in Rod-Coil Block Copolymers   总被引：1，自引：0，他引：1  

JT Chen  EL Thomas  CK Ober  G Mao 《Science (New York, N.Y.)》1996,273(5273):343-346

Rod-coil block copolymers are self-assembling polymers that combine the physics of orientational ordering of rodlike polymers and the microphase separation of coil-coil block copolymers. Several new solid-state morphologies were observed in a series of anionically synthesized model poly(hexyl isocyanate-b-styrene) rod-coil diblock copolymers examined by transmission electron microscopy and selected-area electron diffraction. The rod-coils formed smectic C-like and O-like morphologies with domain sizes ranging from tens of nanometers to almost 1 micrometer. Both structural and orientational changes were found for increasing rod volume fractions. In addition, some morphologies exhibited spontaneous long-range orientational order over many tens of micrometers.  相似文献   

Disruption of the caudal component of the reciprocal apparatus in two horses     

R S Shoemaker  G S Martin  D J Hillmann  P F Haynes  J R McClure  H L Schneiter 《Journal of the American Veterinary Medical Association》1991,198(1):120-122

Two horses became acutely lame following a fall during strenuous exercise and were diagnosed as having disruption of the caudal component of the reciprocal apparatus. Clinical signs consisted of lameness of the right pelvic limb, characterized by flexion of the hock and simultaneous extension of the stifle. Radiography revealed an avulsion fracture from the supracondylar tuberosity and fossa of the distal portion of the femur in one horse. Clinical and radiographic findings indicated avulsion of the lateral origin of the gastrocnemius and superficial digital flexor muscles. Treatment consisted of stall rest, limb immobilization, and phenylbutazone administration. One horse recovered to soundness and the other deteriorated and was euthanatized.  相似文献   

Bilateral cataract surgery in a Suffolk ewe     

H H Oz  R J McClure  D J Hillman 《The Veterinary record》1986,118(18):512-513

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Preputial hematoma in a stallion     

M A Memon  J J McClure  E A Usenik 《Journal of the American Veterinary Medical Association》1987,191(5):563-564

An 8-year-old Quarter Horse stallion was admitted with a swelling involving the prepuce, dorsal part of the scrotum, and root of the penis. The swelling was first noticed 10 days after breeding, with no evidence that it had resulted from a kick by the mare. The penis was retracted into the prepuce, except for a 10- to 15-cm protrusion of the glans penis. Treatment included warm hydrotherapy, massage, stockinette compression, antidiuretics, antibiotics, penile support, and exercise, without success. At necropsy, a massive preputial hematoma was found extending forward from the root of the penis to 12 cm proximal to the glans penis. The exact origin of the hematoma could not be determined. Most likely, bleeding had originated from the vascular plexus lying subfascially on the surface of the penis outside the intact tunica albuginea or from a branch of the external pudendal artery.  相似文献   

Congenital hypotrichosis in Poll Dorset sheep     

JT MACKIE  B McINTYRE 《Australian veterinary journal》1992,69(6):146-147

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