Ingestive responses to mu and delta opioid receptor agonists in the domestic fowl   总被引：1，自引：0，他引：1  

J F McCormack  D M Denbow 《British poultry science》1989,30(2):327-340

1. Four experiments were conducted using the highly specific mu and delta opioid receptor agonists morphiceptin (B-casomorphin 1-4, amide) or [Met5]-enkephalin, respectively, to evaluate the effect of mu and delta opioid receptor agonists on ingestive behaviour in the domestic fowl. 2. Intracerebroventricular (ICV) administration of 0.625, 1.25, 2.5 and 5.0 micrograms of morphiceptin significantly stimulated drinking, while having no effect on feeding. Intramuscular injection of 0.5, 1.5 and 3.0 mg morphiceptin/kg body weight induced a significant increase in feeding, whereas drinking was not altered. 3. ICV administration of 0.625, 1.25, 2.5 and 5.0 micrograms [Met5]-enkephalin, as well as intramuscular injection of 0.5, 1.5 and 3.0 mg [Met5]-enkephalin significantly stimulated feeding while having no effect on drinking. 4. These results suggest that, in the central nervous system, mu opioid receptor agonists stimulate drinking and delta receptor agonists stimulate feeding. At sites outside the blood-brain barrier, both mu and delta opioid receptor agonists stimulate feeding.  相似文献   

Isolation of Mycoplasma bovis from bovine clinical samples in the Republic of Ireland     

Byrne WJ  McCormack R  Brice N  Egan J  Markey B  Ball HJ 《The Veterinary record》2001,148(11):331-333

Mycoplasma bovis was detected in 134 (18 per cent) of 736 samples of bovine lung tissue collected from fatal pneumonia cases in the Republic of Ireland between April 1995 and December 1998. The cases occurred in 95 herds and recurred in four of them. Other respiratory pathogens were identified in 66 per cent of the M bovis-positive cases, with Pasteurella species, infectious bovine rhinotracheitis and parainfluenza 3 virus being most frequently detected. Mastitis and arthritis were less common clinical signs associated with M bovis infection; 22 cases of M bovis mastitis and five cases of M bovis arthritis were diagnosed in five herds.  相似文献   

Clinical haematology and biochemistry profiles of cattle naturally infected with Theileria orientalis Ikeda type in New Zealand     

KE Lawrence  SF Forsyth  BL Vaatstra  AMJ McFadden  DJ Pulford  K Govindaraju 《New Zealand veterinary journal》2018,66(1):21-29

AIMS: To present the haematology and biochemistry profiles for cattle in New Zealand naturally infected with Theileria orientalis Ikeda type and investigate if the results differed between adult dairy cattle and calves aged <6 months.

METHODS: Haematology and biochemistry results were obtained from blood samples from cattle which tested positive for T. orientalis Ikeda type by PCR, that were submitted to veterinary laboratories in New Zealand between October 2012 and November 2014. Data sets for haematology and biochemistry results were prepared for adult dairy cattle (n=62 and 28, respectively) and calves aged <6 months (n=62 and 28, respectively), which were matched on the basis of individual haematocrit (HCT). Results were compared between age groups when categorised by HCT. Selected variables were plotted against individual HCT, and locally weighted scatterplot smoothing (Loess) curves were fitted to the data for adult dairy cattle and calves <6 months old.

RESULTS: When categorised by HCT, the proportion of samples with HCT <0.15 L/L (severe anaemia) was greater for adult dairy cattle than for beef or dairy calves, for both haematology (p<0.002) and biochemistry (p<0.001) submissions. There were differences (p<0.05) between adult dairy cattle and calves aged <6 months in the relationships between HCT and red blood cell counts, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentrations, lymphocyte and eosinophil counts, and activities of glutamate dehydrogenase and aspartate aminotransferase. In both age groups anisocytosis was frequently recorded. The proportion of blood smears showing mild and moderate macrocytosis was greater in adults than calves (p=0.01), and mild and moderate poikilocytosis was greater in calves than adults (p=0.005).

CONCLUSIONS AND CLINICAL RELEVANCE: The haematology and biochemistry changes observed in cattle infected with T. orientalis Ikeda type were consistent with extravascular haemolytic anaemia. Adult dairy cattle were more likely to be severely anaemic than calves. There were differences in haematology and biochemistry profiles between adult dairy cattle and calves, but most of these differences likely had a physiological rather than pathological basis. Overall, the haematological changes in calves aged <6 months appeared less severe than in adult dairy cattle.  相似文献   

Anal fibropapillomas containing bovine papillomavirus type 2 DNA in two groups of heifers     

JS Munday  AA Cullum  NA Thomson  M Bestbier  T McCormack  AF Julian 《New Zealand veterinary journal》2018,66(5):267-271

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1   总被引：1，自引：0，他引：1  

Hacein-Bey-Abina S  Von Kalle C  Schmidt M  McCormack MP  Wulffraat N  Leboulch P  Lim A  Osborne CS  Pawliuk R  Morillon E  Sorensen R  Forster A  Fraser P  Cohen JI  de Saint Basile G  Alexander I  Wintergerst U  Frebourg T  Aurias A  Stoppa-Lyonnet D  Romana S  Radford-Weiss I  Gross F  Valensi F  Delabesse E  Macintyre E  Sigaux F  Soulier J  Leiva LE  Wissler M  Prinz C  Rabbitts TH  Le Deist F  Fischer A  Cavazzana-Calvo M 《Science (New York, N.Y.)》2003,302(5644):415-419

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Contributions to breadmaking of inherent variations in lipid content and composition of wheat cultivars. I. Results of survey     

G. McCormack  J. Panozzo  F. Bekes  F. MacRitchie 《Journal of Cereal Science》1991,13(3)

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波尔山羊耳成纤维细胞的分离培养与保存   总被引：1，自引：0，他引：1  

陈华  朱必龙  章孝荣 《黑龙江动物繁殖》2007,15(3):7-10

本文研究了波尔山羊耳成纤维细胞的体外培养,包括分离纯化和生长特征,同时还研究了成纤维细胞的冷藏和冷冻保存.结果表明,波尔山羊耳成纤维细胞贴壁生长,一般经历潜伏期、指数增生期和平台期;4℃体外冷藏时间为5 d;冷冻保存时4℃平衡1 h、-80℃过夜,然后直接投入液氮中,解冻后培养得到61.6%的贴壁率.  相似文献