Pulmonary lymphomatoid granulomatosis in a cat.     

B A Valentine  J T Blue  J F Zimmer  A E Yeager  S P McDonough 《Journal of veterinary diagnostic investigation》2000,12(5):465-467

Pulmonary lymphomatoid granulomatosis was diagnosed in a 9-year-old castrated male domestic shorthair cat with a history of coughing, lethargy, and anorexia. Radiographic examination revealed multiple pulmonary opacities, consolidation of left lung lobes, and enlarged tracheobronchial lymph nodes. Cytologic examination of impression smears of abnormal pulmonary tissue revealed erythrocytes, lymphocytes, and macrophages, with scattered atypical lymphocytes and binucleate cells. Histopathologic evaluation of abnormal lung tissue revealed multiple, coalescing, densely cellular nodules composed of anaplastic and pleomorphic lymphocytes, with scattered binucleate and multinucleate cells. Marked infiltration and effacement of bronchiolar and vascular smooth muscle were present. These features are characteristic of lymphomatoid granulomatosis. To the authors' knowledge, this is the first report of pulmonary lymphomatoid granulomatosis in a cat.  相似文献   

Sustainable Environmental Education for a Sustainable Environment: Lessons from Thailand for Other Nations     

J. Gallagher  C. Wheeler  M. McDonough  B. Namfa 《Water, air, and soil pollution》2000,123(1-4):489-503

The Thailand Ministry of Education and Michigan State University collaborated to plan, design, implement, and evaluate this project in which school children and adults in 11 communities worked together to prevent forest degradation and improve forest quality. School children in grades 5 though 8 studied the causes and consequences of deforestation and forest degradation and brought the results of their investigations to local community members. This resulted in identification of local environmental problems that were forest-related and joint efforts in which adults and children worked together to resolve these problems. The results of this intergenerational work were very promising as children, adults, schools, communities, and the environment benefited from collaboration. Important lessons for others embarking this work are reported.  相似文献   

Helicobacter felis infection in dogs: effect on gastric structure and function.     

K W Simpson  P L McDonough  D Strauss-Ayali  Y F Chang  P Harpending  B A Valentine 《Veterinary pathology》1999,36(3):237-248

The relationship of Helicobacter felis, an organism that is observed in the stomachs of dogs, to gastric disease in dogs is unclear. The objective of this study was to determine if Helicobacter felis infection alters gastric morphology and gastric secretory function in dogs. Five specific-pathogen-free (SPF), Helicobacter-free Beagle dogs were examined before and for 26 weeks after inoculation with H. felis (ATCC 49179). Three SPF uninfected dogs served as controls. All five dogs became colonized by H. felis as determined by urease activity, histopathology, polymerase chain reaction, and transmission electron microscopic examination of serial gastric biopsies. The degree of colonization ranged from < 1 organism/400 x field to > 10 organisms/400 x field. The fundus, body, and cardia were most heavily colonized. Evaluation of gastric biopsies showed mild gastric inflammation and lymphoid follicles in both infected and uninfected dogs. There was no correlation between the number of organisms observed and the degree of gastric inflammation or number of lymphoid follicles. The gastric secretory axis, assessed by fasting and meal-stimulated plasma gastrin, mucosal gastrin and somatostatin immunoreactivity, fasting gastric pH, and pentagastrin-stimulated gastric acid secretion, was similar in both infected and uninfected dogs. Fasting gastric pH was not a reliable indicator of gastric secretory function. These findings suggest that H. felis may not be a gastric pathogen in dogs. However, the density of colonization and limited duration of infection should be considered when interpreting these findings.  相似文献   

Asymmetric scattering of polarized electrons by organized organic films of chiral molecules     

K Ray  SP Ananthavel  DH Waldeck  R Naaman 《Science (New York, N.Y.)》1999,283(5403):814-816

Electron transmission experiments demonstrate a large asymmetry in the scattering probability of polarized electrons by thin organized films of chiral molecules. This large asymmetry results from the interaction of the electron's wavefunction with many scatterers (molecules) in the organized monolayer structure and represents a manifestation of quantum interference on the scale of supramolecular lengths.  相似文献   

Cooking Characteristics and Quality of Noodles from Food Sorghum     

E. L. Suhendro  C. F. Kunetz  C. M. McDonough  L. W. Rooney  R. D. Waniska 《Cereal Chemistry》2000,77(2):96-100

Three white food sorghums, ATx631*RTx436, ATxARG*RTx436, and SC283‐14, were decorticated, milled into flour and processed into 100% sorghum noodles. Flour, water, and salt (1%) were preheated using a hotplate or a microwave oven. The mixtures were put through a forming extruder to produce noodles. Extruded noodles were dried by three methods: air‐dry method (23°C, 48 hr); one‐stage (60°C, 30% rh, 3 hr), or two‐stage (60°C, 100% rh for 2 hr followed by 60°C, 30% rh for 2 hr). Noodles were evaluated dry and after cooking. Sorghum flours with smaller particle sizes yielded better noodles. The microwave preheating method yielded better noodles than the hot‐plate method. Stronger and firmer noodles, dry or cooked, were prepared using two‐stage drying compared with the other drying methods. Fine flour that was preheated using a microwave oven and dried using the two‐stage method gave the best noodles with moderate (10%) dry matter loss. Optimized processing conditions yielded sorghum noodles with good qualities when properly cooked.  相似文献