Antimicrobial activity of Chenopodium botrys essential oil     

Maksimović ZA  Dordević S  Mraović M 《Fitoterapia》2005,76(1):112-114

Essential oil, isolated by hydrodistillation from Chenopodium botrys aerial parts, expressed significant bactericidal and fungicidal activity against selected strains of microorganisms.  相似文献   

Salmonella SipA polymerizes actin by stapling filaments with nonglobular protein arms     

Lilic M  Galkin VE  Orlova A  VanLoock MS  Egelman EH  Stebbins CE 《Science (New York, N.Y.)》2003,301(5641):1918-1921

Like many bacterial pathogens, Salmonella spp. use a type III secretion system to inject virulence proteins into host cells. The Salmonella invasion protein A (SipA) binds host actin, enhances its polymerization near adherent extracellular bacteria, and contributes to cytoskeletal rearrangements that internalize the pathogen. By combining x-ray crystallography of SipA with electron microscopy and image analysis of SipA-actin filaments, we show that SipA functions as a "molecular staple," in which a globular domain and two nonglobular "arms" mechanically stabilize the filament by tethering actin subunits in opposing strands. Deletion analysis of the tethering arms provides strong support for this model.  相似文献