Effect of Recombinant Bovine Somatotropin on Plasma Concentrations of Insulin‐like Growth Factor I,Insulin and Membrane Integrity of Bull Spermatozoa     

MB Vieira  I Bianchi  EM Madeira  VFB Roll  CA Oliveira  P Viau  I Pivato  NC Severo  FAB Del Pino  A Schneider  MN Corrêa 《Reproduction in domestic animals》2010,45(6):1110-1113

This study aimed to evaluate the effect of the exogenous recombinant bovine somatotropin (rbST) on plasma concentrations of insulin‐like growth factor I (IGF‐I), insulin and semen quality of bulls. Twenty bulls (Aberdeen Angus and Brangus) were divided by breed into two groups. Placebo group was injected with NaCl 0.9% (s.c.) and treatment group with rbST (s.c., 500 mg) at days 0 and 14 of the experiment. Immediately after semen collection, blood samples were taken on days 0, 14, 28, 42 and 56 of the experiment. Semen was also collected on day 70 of the experiment. Evaluation of sperm motility was performed at pre‐freezing and post‐thawing stage, whereas assessment of sperm membrane integrity was performed after freezing and thawing. Analysis of data revealed that the effect of treatment and treatment‐by‐collection day on plasma concentrations of IGF‐I and insulin was not significant. However, mean plasma concentrations of IGF‐I and insulin were affected (p < 0.0001) by days of blood sampling. Effect of treatment and treatment‐by‐collection day on motility of spermatozoa was similar (p > 0.05) at pre‐freezing and post‐thawing stage. Intactness of plasmalemma and tail membrane of spermatozoa at post‐thawing stage was higher (p < 0.05) in rbST‐treated group than in control. In conclusion, rbST did not affect plasma concentrations of IGF‐I and insulin, however, it did improve post‐thaw sperm membrane integrity.  相似文献   

Clinical management of Brucella suis infection in dogs and implications for public health          下载免费PDF全文

DR James  G Golovsky  JM Thornton  L Goodchild  M Havlicek  P Martin  MB Krockenberger  DJE Marriott  V Ahuja  R Malik  SM Mor 《Australian veterinary journal》2017,95(1-2):19-25

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DOPPLER MEASUREMENT OF HEPATIC ARTERIAL FLOW IN DOGS: TECHNIQUE AND PRELIMINARY FINDINGS     

C.R. Lamb  MA  Vet MB  C.A. Burton  BVet Med  C.H. Carlisle  MVSc  DVR FACVS 《Veterinary radiology & ultrasound》1999,40(1):77-81

The common hepatic artery in 10 healthy adult beagles, 20 healthy pups (13 Deerhounds and seven Irish Wolfhounds), and seven dogs with either a congenital or acquired hepatic disorder was examined by duplex-Doppler ultrasonography. Peak systolic velocity (Vs), resistive index (RI), pulse rate, angle of insonation, and sample volume depth were recorded. Measurements in Beagles were made after a 24 h fast and repeated 2 h after feeding. The mean Vs and RI in fasted Beagles were 1.5 m/s (range 1.1-2.3 m/s) and 0.68 (range 0.62-0.74), respectively. Postprandially, there were no significant differences in any of these variables. Mean Vs and RI were lower in pups: 1.0 m/s (range 0.8-1.3 m/s) and 0.59 (range 0.46-0.65), respectively (P < .001). Two dogs with congenital arterioportal fistula had higher mean Vs (P < .001) and lower mean RI (P < .05) than normal pups. No significant differences were detected between normal Beagles, three dogs with portal vein thrombosis, and two dogs with acquired hepatic insufficiency. Differences in measured hepatic blood flow in dogs of different age or breed will complicate diagnostic use of hepatic arterial Doppler measurements.  相似文献   

Decreased ivermectin and moxidectin sensitivity in Haemonchus contortus selected with moxidectin over 14 generations.   总被引：1，自引：0，他引：1  

M B Molento  G T Wang  R K Prichard 《Veterinary parasitology》1999,86(1):77-81

Ivermectin resistance in the nematode Haemonchus contortus has been reported in many parts of the world and many ivermectin resistant isolates have been found to have reduced sensitivity to moxidectin. However, it is unclear whether parasites that are selected with moxidectin would demonstrate reduced sensitivity to ivermectin. In this study, the effects of moxidectin and ivermectin on an unselected strain and a strain of H. contortus derived from the unselected strain but selected over 14 generations with moxidectin, were compared in jirds. The recovery of adult worms and fourth stage (L4) larvae following treatment were compared between strains and anthelmintics. Moxidectin-selected H. contortus showed reduced sensitivity to ivermectin as well as to moxidectin. Doses of 0.1 mg/kg of moxidectin and 0.4 mg/kg of ivermectin were necessary to obtain an efficacy of 95% or above against the moxidectin-selected strain of H. contortus compared with 0.025 mg/kg for moxidectin and 0.1 mg/kg for ivermectin required for a similar efficacy in the unselected strain.  相似文献   

Multidrug and multispecies resistance in sheep flocks from São Paulo state, Brazil     

Veríssimo CJ  Niciura SC  Alberti AL  Rodrigues CF  Barbosa CM  Chiebao DP  Cardoso D  da Silva GS  Pereira JR  Margatho LF  da Costa RL  Nardon RF  Ueno TE  Curci VC  Molento MB 《Veterinary parasitology》2012,187(1-2):209-216

The economic importance of sheep production is increasing worldwide simultaneously with the emergence of parasitic resistance. This study aimed to survey the current situation of management practices and parasite resistance in sheep flocks in S?o Paulo state, Brazil. A questionnaire was given to 35 sheep farmers to obtain information related to flock management practices. Of these flocks, 30 were submitted to the fecal egg count reduction test (FECRT) with at least one of the five following anthelmintics: albendazole, closantel, ivermectin, levamisole, and moxidectin, for comparison against an untreated control group. In the survey, the median number animals per flock was 301, mainly of the Santa Ines breed (in 75.8% of the flocks) and crossbred animals (in 54.5% of the flocks). The predominant farming system was semi-intensive (82.9%), using rotational grazing (80%). Selective treatment was based on FAMACHA grade (47.1%) and in clinical signs (41.2%). The most often applied anthelmintics were macrocyclic lactones (42.9-54.2% in the last three applications). Considering the anthelmintics employed in this study, 10.7% of the farms' flocks were resistant to three, 35.7% to four, and 53.6% to all five anthelmintics. The main helminth genera observed before and after treatments were Haemonchus sp. (75.8%) and Trichostrongylus sp. (19.1%), but all observed genera (Cooperia sp., Oesophagostomum sp., and Strongyloides sp.) were detected by the FECRT. Considering efficacy values less than or equal to 90% in the FECRT as resistant, 100% of flocks were resistant to albendazole and ivermectin, 96.6% to moxidectin, 92.9% to closantel, and 53.6% to levamisole. It is thus possible to conclude that multidrug resistance is widespread in sheep flocks in S?o Paulo state, Brazil, and this involves all prevalent helminth genera.  相似文献   

Trephination of the Frontal Sinuses and Instillation of Clotrimazole Cream: A Computed Tomographic Study in Canine Cadavers     

Martin Baker BSc CertPG  Lindsay White MA Vet MB 《Veterinary surgery : VS》2013,42(3):322-328

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A preliminary investigation comparing pre-operative morphine and buprenorphine for postoperative analgesia and sedation in cats   总被引：2，自引：1，他引：1  

GW Stanway BVSC  Cert VA    PM Taylor MA  Vet MB  PhD  DVA  Dip ECVA  & DC Brodbelt† MA  Vet MB  DVA  Dip ECVA  MRCVS 《Veterinary anaesthesia and analgesia》2002,29(1):29-35

Objective To compare the postoperative analgesic and sedative properties of buprenorphine and morphine in cats. Study Design Prospective, randomized, blinded study. Animals Thirty‐two domestic cats undergoing surgery. Methods Cats received pre‐anaesthetic medication with acepromazine (0.05 mg kg^?1) given intramuscularly and were randomly allocated to group M and given morphine (0.1 mg kg^?1) intramuscularly (IM) or to group B and given buprenorphine (0.01 mg kg^?1) IM. Anaesthesia was induced with propofol and maintained with halothane in oxygen and nitrous oxide. Pain and sedation scores using visual analogue scales, and heart and respiratory rates, were measured immediately before, and 30, 60, 120, 180, 300 and 420 minutes after anaesthesia. Results Pain scores were significantly lower at 60, 120 and 180 minutes after anaesthesia in group B. Group B also had higher heart rates at 30 minutes. There were no other statistically significant differences between the groups. Clinical relevance Buprenorphine (0.01 mg kg^?1) appeared to provide better postoperative analgesia than morphine (0.1 mg kg^?1) and may also have a longer duration of action.  相似文献   

BALLOON DILATATION OF NASOPHARYNGEAL STENOSIS IN A CAT     

Adrian  Boswood  Vet MB  Christopher R.  Lamb  Vet MB  Daniel J.  Brockman  BVSC  Panagiotis  Mantis  DVM  Angela L.  Witt  DVM 《Veterinary radiology & ultrasound》2003,44(1):53-55

A cat was diagnosed with nasopharyngeal stenosis on the basis of clinical signs, survey and contrast radiography, endoscopy and magnetic resonance imaging. The condition was successfully managed with repeated balloon dilatation.  相似文献   

Correlation Between Histopathologic,Arthroscopic, and Magnetic Resonance Imaging Findings in Dogs With Medial Coronoid Disease          下载免费PDF全文

Vincent Wavreille DVM  Wm Tod Drost DVM  Diplomate ACVR  Duncan Russell BVMS  Diplomate ACVP  Matthew J. Allen Vet MB  PhD 《Veterinary surgery : VS》2015,44(4):501-510

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Collection and Propagation Methods for Mesenchymal Stromal Cells     

Sarah E. Taylor BVM&S  MSc  PhD  Cert ES  MRCVS  Peter D. Clegg MA  Vet MB  PhD 《Veterinary Clinics of North America: Equine Practice》2011,27(2):263-274

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