Does thalidomide prolong survival in dogs with splenic haemangiosarcoma?          下载免费PDF全文

J. P. Bray  G. Orbell  N. Cave  J. S. Munday 《The Journal of small animal practice》2018,59(2):85-91

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Anal fibropapillomas containing bovine papillomavirus type 2 DNA in two groups of heifers     

JS Munday  AA Cullum  NA Thomson  M Bestbier  T McCormack  AF Julian 《New Zealand veterinary journal》2018,66(5):267-271

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Pathology of 2-alkyl and 2-hydroxy naphthoquinone toxicity in rats     

B.L. Smith  R. Munday 《New Zealand veterinary journal》2013,61(3)

Extract

The oral administration of 2-methyl-1, 4-naphthoquinone (menadione) to rats caused oxidative destruction of the erythrocyte. Heinz body formation occurred in erythrocytes, lowered PCVs and haemoglobin Occurred in blood, with splenic and hepatic erythroclasis, and iron conservation in the spleen, liver and kidney. These effects diminished when increasingly large alkyl substitutions of the methyl group of thi naphthoquinone were made. No effect was caused by the 2-decyl derivative.  相似文献   

Vaccination-site sarcomas in cats in New Zealand     

D Aberdein  JS Munday  CB Dyer  CG Knight  AF French  IR Gibson 《New Zealand veterinary journal》2013,61(1)

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A real-time polymerase chain reaction assay for the detection of Mycoplasma agalactiae     

J Fitzmaurice  M Sewell  CM King  S McDougall  WL McDonald  JS O'Keefe 《New Zealand veterinary journal》2013,61(5):233-236

AIM: To develop a real-time PCR for the detection of Mycoplasma agalactiae, using PCR primers targeting the ma-mp81 gene.

METHODS: A group of 15 M. agalactiae isolates, 21 other Mycoplasma spp. isolates and 21 other bacterial isolates was used in evaluation of the assay.

RESULTS: All M. agalactiae isolates were detected by the assay and none of the non-target isolates was amplified. The analytical detection limit of the assay was 10 fg of purified genomic DNA and 10⁴ cfu/ml milk inoculated with M. agalactiae. When applied to goat-milk samples collected from three herds free of M. agalactiae infection, the assay had a specificity of 100%.

CONCLUSIONS: The assay would be useful in a diagnostic laboratory, providing specific, sensitive and rapid detection of M. agalactiae.  相似文献   

Black-hair follicular dysplasia in a New Zealand Huntaway dog     

JS Munday  AF French  GRK McKerchar 《New Zealand veterinary journal》2013,61(3):170-172

CASE HISTORY: A 6-year-old intact male New Zealand Huntaway dog had slowly progressive alopecia that was first observed at 12 weeks of age.

CLINICAL FINDINGS: Patchy alopecia was confined to the black-haired areas of the body, and was most evident on the head and dorsum of the body; tan-haired areas of skin appeared normal. Histological examination of black-haired skin revealed distended melanocytes and large aggregates of melanin within, and surrounding, the hair follicles and the epidermis. Macrophages distended with melanin were also visible within the perifollicular and superficial dermis, and follicular lumina were often plugged by keratin that contained aggregates of melanin. The follicles were dysplastic and few hair shafts were visible emerging from follicular infundibula within the sections.

DIAGNOSIS: The clinical and histological findings were consistent with black-hair follicular dysplasia (BHFD).

CLINICAL RELEVANCE: This is the first report of BHFD in a dog in New Zealand, and is the first report in a Huntaway. The most significant effect of BHFD is a predisposition to follicular plugging and secondary bacterial skin infections. Due to the hereditary nature of the follicular dysplasias, breeding from affected dogs should be discouraged. Histological examination of the skin is required to differentiate between the different follicular dysplasias as well as differentiating between follicular dysplasia and follicular atrophy due to endocrinopathy.  相似文献   

Confirmation of the occurrence of the nematode parasite Lamanema chavezi Becklund, 1963 in South American camelids in New Zealand     

PB McKenna  C Morley  M Koning  JS Tahana  MJ Taylor 《New Zealand veterinary journal》2013,61(6):395-396

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Disseminated Mortierella wolfii infection in a neonatal calf     

JS Munday  AG Wolfe  KE Lawrence  SK Pandey 《New Zealand veterinary journal》2013,61(1):62-63

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Comparison between S(+) ketamine–diazepam and S(+) ketamine–midazolam on anesthetic induction and recovery in dogs     

FB  Riviera  JS Pires 《Veterinary anaesthesia and analgesia》2003,30(2):101-101

S(+) ketamine, one of the two enantiomers of racemic ketamine, is a phencyclidine derivative that induces amnesia and analgesia. Its activity is related to blockade of NMDA receptors and some opioid action. We compared anesthetic induction and recovery quality with S(+) ketamine in combination with diazepam or midazolam in 10 dogs (ASA 1) admitted for elective surgery. After all clinical examinations, the dogs were separated into two groups (G I and G II). All animals received acepromazine (0.1 mg kg^?1) and fentanyl (5 µg kg^?1) IM, 20 minutes before induction with S(+) ketamine (6 mg kg^?1) and diazepam (0.5 mg kg^?1) IV (G I) or midazolam 0.2 mg kg^?1 (G II) IV. The doses of diazepam and midazolam were chosen according to the literature. All dogs were intubated and then maintained with halothane in oxygen at a vaporizer setting sufficient to maintain surgical anesthesia. Quality of induction, time needed for intubation, heart rate, respiratory rate, SpO₂, time to extubation, and quality of recovery were evaluated. The results were analyzed by Student's t‐test. Smooth induction and recovery were observed in all animals. The time to intubation was 45 ± 20 (GI) and 25 ± 6 seconds (GII), HR was 122 ± 12 (GI) and 125 ± 7 beats minute^?1 (GII), RR was 17 ± 2 (GI) and 21 ± 3 breaths minute^?1 (GII), SpO₂ was 96 ± 2 (GI) and 94 ± 1% (GII), time to extubation was 7 ± 3 (GI) and 4 ± 1 minutes (GII). No statistical differences were found in analyses, although time to intubation was less in GII. The results suggested that both combinations could be used safely for anesthetic induction in healthy dogs.  相似文献   

Effects of Female Dietary Restriction in a Rabbit Growth Line During Rearing on Reproductive Performance and Embryo Quality          下载免费PDF全文

C Naturil‐Alfonso  R Lavara  JS Vicente  F Marco‐Jiménez 《Reproduction in domestic animals》2016,51(1):114-122

Maternal diet prior to mating has an effect on reproductive performance. We analysed the effect of maternal dietary restriction during rearing on reproductive performance, the embryo development and foetal growth. Females were categorized in two groups: (i) does with ad libitum access to feed or (ii) restricted. Two experiments were performed: (i) after 1 month, receptive females from both experimental groups were artificially inseminated and the reproductive performance was recorded during three reproductive cycles; at the first insemination, the body weight and perirenal fat thickness were recorded, and (ii) females from both experimental groups were inseminated, and 24 h later, embryos were recovered and transferred to recipient females from a maternal line. Later, embryonic implantation was assessed at day 14 by laparoscopy and foetal growth was monitored by ultrasound examination. In experiment 1, no differences in kindling rate was found, but prolificacy was showed to be higher in ad libitum does, which also were heavier than restricted ones. In experiment 2, no differences among does either in body weight, in perirenal fat thickness or in reproductive performance (ovulation rate and embryo recovery rate) were related to differences in feed intake. However, despite similar embryonic implantation losses, embryos from restricted females demonstrated higher foetal and gestational losses. Embryos from restricted does presented lower foetal growth than embryos from ad libitum does. Therefore, our results demonstrated that nutrition before first conception in a rabbit line selected for growth rate may impact on the embryo and results in a disturbance in gestational losses and foetal growth over all reproductive life.  相似文献