Efficacy of a substituted methyl benzimidazole carbamate against developing and adult helminth parasites     

J C Katiyar  A Misra  S Gupta  P K Visen  P K Murthy  A B Sen 《Veterinary parasitology》1987,23(3-4):193-204

The efficacy of a substituted methyl benzimidazole carbamate, methyl 5(6)-[4-N-(2-pyridyl)] piperazino carbamoyl benzimidazole-2-carbamate, was assessed against larval and adult forms of Ancylostoma ceylanicum (hookworm), Nippostrongylus brasiliensis (trichostrongylid), Hymenolepis nana (tapeworm) and Brugia malayi (filariid) in experimentally-infected animals. The compound was found to have high efficacy against the developing stages (L3, L4, L5) of A. ceylanicum in hamsters at a single dose of 12.5 mg kg-1, against larvae of N. brasiliensis at 17.5 mg kg-1 and against cysticercoids of Hymenolepis nana at 100 mg kg-1 daily for 3 days given per os (p.o.) or intraperitoneally (i.p.). All the stages of B. malayi in Mastomys were killed when the compound was given i.p. at a dose of 6.25 mg kg-1 for 5 consecutive days. A dose of 6.25 mg kg-1 eliminated all adult A. ceylanicum from infected hamsters, 100 mg kg-1 resulted in complete removal of Syphacia obvelata adults from 63.6% of infected mice, 25 mg kg-1 X 5 dose eliminated 100% of adult B. malayi from infected Mastomys and a single 50 mg kg-1 dose expelled all H. nana adults from infected rats.  相似文献   

Prevalence of Salmonella spp in cull (market) dairy cows at slaughter.     

H F Troutt  J C Galland  B I Osburn  R L Brewer  R K Braun  J A Schmitz  P Sears  A B Childers  E Richey  E Mather  M Gibson  K Murthy  A Hogue 《Journal of the American Veterinary Medical Association》2001,219(9):1212-1215

OBJECTIVE: To determine the prevalence of Salmonella spp in the cecal-colon contents of cull (market) dairy cows at slaughter because of potential public health ramifications. DESIGN: Survey study. SAMPLE POPULATION: Cecal-colon contents collected from 5,087 cull (market) dairy cows at slaughter at 5 slaughter establishments across the United States. PROCEDURE: During 2 periods of the year, winter (January and February) and summer (July through September), 5 cull (market) cow slaughter establishments in the United States--west (WE), southeast (SEE), central (CE), north central (NCE), and south central (SCE)--establishments were visited, and cecal-colon contents of cull dairy cows were obtained at the time of slaughter. Samples were examined by microbiologic culture at a single laboratory for Salmonella spp. RESULTS: Salmonella spp were detected in 23.1% of cecal-colon content samples from cull dairy cows across the 5 slaughter establishments. The highest site prevalence (54.5%) was detected at the WE during the summer period, whereas the lowest was found at the CE during the summer (4.3%) and at the NCE during the winter (4.5%). Considerable variation in the daily prevalence of Salmonella spp was found, particularly at the WE and the SCE. Salmonella spp were isolated from 93% of cecal-colon contents collected on a summer day at the WE. CONCLUSIONS AND CLINICAL RELEVANCE: Results strongly suggest that there is a high prevalence of Salmonella spp in cull dairy cows at slaughter, which could burden Hazard Analysis Critical Control Point programs implemented in slaughter establishments. Procedures to reduce Salmonella load at the dairy farm and during transport to slaughter could reduce the risk of spread during the slaughter process.  相似文献   

Analysis of phenotypic variation and selection of superior genotypes of Balanites roxburghii Planch. from South India     

Yadav  Guggalada Govardhana  Murthy  Hosakatte Niranjana 《Genetic Resources and Crop Evolution》2022,69(5):1993-2009

Genetic Resources and Crop Evolution - Balanites roxburghii Planch. is an important medicinal plant of India and used in the treatment of various diseases and disorders. Seeds possess a high amount...  相似文献   

Diversity of wood-apple (Limonia acidissima L., Rutaceae) genetic resources in South India     

Lamani  Shrinivas  Murthy  Hosakatte Niranjana 《Genetic Resources and Crop Evolution》2022,69(8):2929-2946

Genetic Resources and Crop Evolution - Wood-apple (Limonia acidissima L.) is an undomesticated nutritionally and medicinally potential monotypic tree species of the genus Limonia, which belongs to...  相似文献   

WHOLE‐BODY BIODISTRIBUTION OF 3′‐DEOXY‐3′‐[18F]FLUOROTHYMIDINE (18FLT) IN HEALTHY ADULT CATS     

Joshua A. Rowe  Federica Morandi  Jonathan S. Wall  Murthy Akula  Stephen J. Kennel  Dustin Osborne  Emily B. Martin  Gina D. Galyon  Misty J. Long  Alan C. Stuckey  Amy K. LeBlanc 《Veterinary radiology & ultrasound》2013,54(3):299-306

Positron emission tomography/computed tomography (PET/CT) utilizing 3′‐deoxy‐3′‐[¹⁸F]fluorothymidine (¹⁸FLT), a proliferation tracer, has been found to be a useful tool for characterizing neoplastic diseases and bone marrow function in humans. As PET and PET/CT imaging become increasingly available in veterinary medicine, knowledge of radiopharmaceutical biodistribution in veterinary species is needed for lesion interpretation in the clinical setting. The purpose of this study was to describe the normal biodistribution of ¹⁸FLT in adult domestic cats. Imaging of six healthy young adult castrated male cats was performed using a commercially available PET/CT scanner consisting of a 64‐slice helical CT scanner with an integrated whole‐body, high‐resolution lutetium oxy‐orthosilicate (LSO) PET scanner. Cats were sedated and injected intravenously with 108.60 ± 2.09 (mean ± SD) MBq of ¹⁸FLT (greater than 99% radiochemical purity by high‐performance liquid chromatography). Imaging was performed in sternal recumbency under general anesthesia. Static images utilizing multiple bed positions were acquired 80.83 ± 7.52 (mean ± SD) minutes post‐injection. Regions of interest were manually drawn over major parenchymal organs and selected areas of bone marrow and increased tracer uptake. Standardized uptake values were calculated. Notable areas of uptake included hematopoietic bone marrow, intestinal tract, and the urinary and hepatobiliary systems. No appreciable uptake was observed within brain, lung, myocardium, spleen, or skeletal muscle. Findings from this study can be used as baseline data for future studies of diseases in cats.  相似文献   

匙羹藤酸在匙羹藤(Gymnema sylvesfre)不同器官的分布     

Shirugumbi Hanamanthagouda Manohar  Poomananda Madhava Naik  Nagella Praveen  Hosakatte Niranjana Murthy 《林业研究》2009,20(3)

利用高效液相色谱法(HPLC)测定匙羹藤(Gymmnema sylvestre)不同器官的匙羹藤酸含量.结果表明:不同器官的匙羹藤酸含量明显小同,在顶芽、花、节点、叶、节间、根和种子的匙羹藤酸含量分别为,54.29、31.66、28.82、27.67、25.39、20.56和1.31 mg·g-1 DW.在幼叶中,匙羹藤酸(35.39 mg·-1DW)含量最高,比老叶的匙羹藤酸(23.07 mg·g DW含量高1.52倍.幼年,中年和老年节间的匙羹藤酸含量分别为26.47、25.77和23.94 mg·g-1DW,均低于叶的匙羹藤酸含量,而幼嫩,中部节和老节点的匙羹藤酸含量分别为27.96、28.81和29.66 mg·g-1 DW,均高于叶的匙羹藤酸含量.因为过度开采引起了这些植物在自然界的损耗,本研究为匙羹藤资源的发展和利用提供了科学依据.  相似文献   

An ethnobotanical survey of medicinal plants used by the Didayi tribe of Malkangiri district of Orissa, India     

Pattanaik C  Reddy CS  Murthy MS 《Fitoterapia》2008,79(1):67-71

An ethnobotanical survey was carried out among the ethnic community (Didayi) in Malkangiri district, Orissa. A total of 53 medicinal plant species belonging to 34 families and 52 different species are described under this study.  相似文献   

Cu离子对巴西橡胶树组织培养的影响   总被引：2，自引：0，他引：2  

王树昌  于晓玲  赵平娟  彭明 《热带农业工程》2010,(6)

巴西橡胶树是重要的经济作物,微量元素Cu对巴西橡胶树组织培养成胚、生根及组培苗生根有重要影响。试验以巴西橡胶树花药为外植体,以改良MSB为基础培养基,改变其中Cu的浓度,进行试验,寻找最佳的微量元素Cu的含量。结果表明:培养基中不同铜元素的添加量,对巴西橡胶树胚状体及组培切苗的生根产生明显的促进及抑制作用。  相似文献   

Determination of Chemical Composition and Nutritive Value with Fatty Acid Compositions of African Mangosteen (<Emphasis Type="Italic">Garcinia Livingstonei</Emphasis>)     

Kadanthottu Sebastian Joseph  Sushma Bolla  Kavita Joshi  Medha Bhat  Krupa Naik  Sridevi Patil  Sreevani Bendre  Brunda Gangappa  Vidya Haibatti  Shivanand Payamalle  Smita Shinde  Yaser Hassan Dewir  Hosakatte Niranjana Murthy 《Erwerbs-Obstbau》2017,59(3):195-202

African mangosteen (Garcinia livingstonei T. Anderson) is native to Africa and is exotic to other parts of the world. It is a fruit bearing tree with multiple uses. This study was purposed to determine, by analysis, the chemical compositions and nutritive value of the fruits of African mangosteen. Proximate compositions varied with the portions such as epicarp, mesocarp, endocarp and seed tested. All fruit portions contained carbohydrate (37.67–95.02%) and crude protein (0.65–31.76%) as their major components. Moisture (0.45–3.42%), crude fat (1.23–19.55%), crude fiber (2.93–21.13%) and ash (1.76–5.44%) were also found at different levels, depending upon the portions. All portions of fruit were rich in macro and micro elements. The fruits also possessed phenolics (174.02–10.725?mg GAE per g), flavonoid (19.25 to 99.98?µg QE per g) and alkaloid (1.56 to 9.49?mg/kg) contents. The constitution of tannins and oxalate which contribute towards the anti-nutritive value was also low, thus making the fruits beneficial for consumption. Quality attributes like relative amount of oleic acid, total unsaturated fatty acid, acid value, free fatty acid, peroxide value and iodine value showed that the seed oil of African mangosteen can become one among the oleic acid based vegetable oils for consumption.  相似文献   

Anaerobic Fluidized Bed Degradation and the Development of a Kinetic Model for a Particulate Organic Matter Enriched Wastewater Sludge     

Saravanane  R.  Murthy  D. V. S.  Krishnaiah  K. 《Water, air, and soil pollution》2001,127(1-4):15-30

The starch manufacturing industrial units, such as sago mills,both in medium and large scale, suffer from inadequate treatment and disposal problems due to high concentration of suspended solids present in the sludge. A laboratory scale study was conducted to investigate the viability of anaerobic treatment of sago waste sludge, enriched in particulate organicmatter, using a fluidized bed reactor. The start-up of the reactor was carried out using a mixture of digested supernatantsewage sludge and cow dung slurry in different proportions. The effect of operating variables such as COD of the effluent, bed expansion, minimum fluidization velocity on efficiency oftreatment and recovery of biogas was investigated. The maximum efficiency of treatment was found to be 82% and the nitrogen enriched digested sludge was recommended for agricultural use. A kinetic model was developed for the degradation of particulate organic matter using the general kinetic equation [dS/dt = K _HC SX_C] which allowed for a more accurate mathematical representation of the hydrolysis process. Analysing data from a series of batch tests, the best fit value of C was found to be in the range 0.43 to 0.62.  相似文献