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141.
Kei’ichiro?IguchiEmail author Katsutoshi?Watanabe Mutsumi?Nishida 《Fisheries Science》2005,71(2):308-313
An increasing demand for stocking of hatchery-reared ayu, Plecoglossus altivelis, has aroused concerns about their genetic status which has an effect on their post-stocking performance and the conservation
of native biodiversity. Instead of costly analysis, fluctuating asymmetry (FA) was examined to test its suitability as an
indirect measure of genetic diversity. Two bilateral traits, pectoral and pelvic fin rays, were targeted, and two wild and
four hatchery populations of ayu were sampled for comparison. Frequency of FA in soft-rays was not similar between specimens
in both pelvic and pectoral fins. The wild populations did not show FA incidences lower than the hatchery populations, suggesting
a considerable degree of environmental stress operating in the wild populations. Comparison between the hatchery populations
showed overall increasing FA incidence with the decrease in genetic diversity, although the correlation was not complete in
detail. In conclusion, FA can be used as a convenient tool to compare genetic status, but quantified evaluation is rather
limited to monitoring changes in the genetic variation within a hatchery population. 相似文献
142.
Yamato SAJIKI Satoru KONNAI Reiko NAGATA Satoko KAWAJI Hayato NAKAMURA Sotaro FUJISAWA Tomohiro OKAGAWA Naoya MAEKAWA Yukinari KATO Yasuhiko SUZUKI Shiro MURATA Yasuyuki MORI Kazuhiko OHASHI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(2):162
Johne’s disease, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic enteritis of ruminants. Previous studies have shown that programmed death-ligand 1 (PD-L1) is associated with the disease progression, and PD-L1 blockade activates MAP-specific Th1 responses in vitro. Here, we performed anti-PD-L1 antibody administration using 2 MAP-infected cattle at the late subclinical stage of infection. After administration, bacterial shedding was reduced or maintained at a low level. Additionally, MAP-specific Th1 cytokine production was upregulated, and CD69 expression was increased in T cells. Collectively, the treatment has a potential as a novel control method against Johne’s disease. 相似文献
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