Quantitative genetics of secondary hip joint osteoarthritis in a Labrador Retriever-Greyhound pedigree     

Hays L  Zhang Z  Mateescu RG  Lust G  Burton-Wurster NI  Todhunter RJ 《American journal of veterinary research》2007,68(1):35-41

OBJECTIVE: To evaluate the quantitative inheritance of secondary hip joint osteoarthritis in a canine pedigree. ANIMALS: 137 Labrador Retrievers, Greyhounds, and mixed-breed dogs. PROCEDURES: Necropsy scores ranging from 0 to 4 were obtained for each hip joint. Seven unaffected Greyhounds with normal hip joint conformation were also used for genetic modeling, but were not euthanized. Sixty-six male and 71 female dogs were allocated to 2 groups (< or = 12 months of age and > 12 months of age). Statistical models were developed to establish the inheritance pattern of hip joint osteoarthritis that developed secondary to hip dysplasia. RESULTS: 62 dogs had evidence of osteoarthritis in a hip joint, and 75 had no evidence of osteoarthritis. After sex was adjusted for, the necropsy score was found to be inherited additively but without dominance. Each Labrador Retriever allele increased the necropsy score by 0.7 to 0.9 points, compared with the Greyhound allele, and male sex increased the necropsy score 0.74 over female sex. Approximately 10% of the variation in necropsy score was attributable to the litter of puppies' origin. CONCLUSIONS AND CLINICAL RELEVANCE: Because secondary hip joint osteoarthritis is inherited additively, selection pressure could be applied to reduce its incidence. Similar statistical models can be used in linkage and association mapping to detect the genes in the underlying quantitative trait loci that contribute to hip joint osteoarthritis.  相似文献   

轮叶沙参的栽培及利用价值   总被引：1，自引：0，他引：1  

鲍业青  宋平 《特种经济动植物》2002,5(4):24-24

轮叶沙参[(Adenopjhora teteaphylla(Thunb.)fisch.]又名沙参、南沙参、牵参、四叶菜、泡沙参、白沙参、苦心、识美、虎须、白参、志取、文虎、文希、羊婆奶、泡参、面杆杖、桔参、稳牙参、保牙参、土人参、铃儿草、山沙参、明叶菜、沙和尚、空沙参、甜桔梗等,是民间传下来的药膳野菜.分布于东北、河北、山东、河南、安徽、江苏、浙江、广东、江西等地,越南北部、朝鲜、日本、俄罗斯也有.喜生于山坡阳处、草丛中,林缘、路边,荒地、草甸、河谷及沙地.  相似文献   

施钾对有些茄科作物产量和品质的影响   总被引：1，自引：0，他引：1  

NI Wu-Zhong  LIANG Jian-She  R. H&#;RDTER 《土壤圈》2001,11(3):251-255

Over a period of two years,field experiments were conducted on wto silty loam soils grown with four solanaceous vegetable crops of geggplant(var.serpentinum Bailey),tomato(var.commune Bailey),sweet pepper(var.grossum Bailey) and chilli (var.lengum Bailey),respectively,Each experiment included four treatments with from low to high doses,0-450 kg ha^-1 for eggplant ,tomato and sweet pepper,and 0-270 kg ha^-1 for chilli,of K fertilizers in the from of sulfate of potash(SOP) applied together with N and P fertilizers. One CK treatment without K,N and P fertilzers applied and one treatment of K fertilizer in the form of muriate of potash(MOP) applied at the high level(450kg ha^-1) together with N and P fertilizers were included in the experiments of eggplant,in order to compare the effects of SOP and MOP,The fruit yields of the tested crops increased significantly with the increasing rate of K application.The crops supplied with K fertilizers yielded more stably as the CV% of their yields decreased with the rate of K application,The K fertilizers yielded more stably as the CV% of their yields decreased with the rate of K application,The dry matter and vitamin C contents in fruits of tomato,sweet pepper and chilli,and the sugar content and the titratable acidity level of tomato fruits were increased,and the S/A ratio( ratio of sugar content to titratable acidity) of tomato fruits were decreased by K fertilization,indicating that K fertilization could improve the fruit quality of the solanaceous vegetable crops.However,the high rate of Kfertilizer might lower the dry matter and vitamin C contents of tomato fruits and sewwt pepper fruits.SOP was more effective than MOP in increasing the yield and quality of eggplant fruits at the high fertilization rate;therefore,the choice of applying SOP may be better for high levels of K fertilization.  相似文献   

南宁市高容积率居住小区园林环境调查及改进方法研究     

王颖  林倩  范泽源  宋平 《广西热带农业》2015,(3)

南宁市作为广西壮族自治区的首府,经济发展迅速,随着近几年城市人口的增加,首府的高容积率小区也大量的迅速崛起.然而过高的容积率下,居住小区的环境质量出现了若干问题,影响了居民的身心健康.从调查的时效性考虑,此次调查是以南宁市2000年以来的部分高容积率居住小区为对象,对南宁市3个城区的23个小区进行调查,通过统计与分析调查结果,发现高容积率小区的园林环境通过合理设计也可以获得舒适的人居环境,来保证居民的身心健康.  相似文献   

Evaluation of Curvularia lunata Strain B6 as a Potential Mycoherbicide to Control Barnydrgrass （Echinochloa crus-galli）     

LI Jing  WEI Tao  SUN  Ai-rui NI  Han-wen 《中国农业科学(英文版)》2013,(7):1201-1207

The virulent strain B6 of Curvularia lunata was screened out from 65 fungus strains isolated from the diseased leaves of barnyardgrass (Echinochloa crus-galli). Greenhouse and field studies were conducted to evaluate the feasibility of the strain being exploited as a mycoherbicide for barnyardgrass control in paddy fields. The results of pathogenicity experiments showed that this strain was highly pathogenic to barnyardgrass at the 1- to 2.5-leaf stages. The fresh weight reduction increased with the increase of inoculated conidial concentrations and the prolongation of dew duration. Strain B6 provided excellent barnyardgrass control when it was applied at the concentration of 1×104-1×106 conidia mL-1 in paddy fields with water layer. This strain was very safe to rice and the most plant species except wheat, barley and corn. Findings of this study indicated that this strain could be a potential mycoherbicide for barnyardgrass control in paddy fields in the future.  相似文献   

Exogenous Application of Abscisic Acid or Gibberellin Acid Has Different Effects on Starch Granule Size Distribution in Grains of Wheat     

PENG Dian-liang  CAI Tie  YIN Yan-ping  YANG Wei-bing  NI Ying-li  YANG Dong-qing  WANG Zhen-lin 《中国农业科学(英文版)》2013,(9):1551-1559

Granule size distribution of wheat starch is an important characteristic that can affect its chemical composition and the functionality of wheat products. Two high-yield winter wheat cultivars were used to evaluate the effects of the application of exogenous ABA or GA during the reproductive phase of the initial grain filling on starch granule size distribution and starch components in grains at maturity. The results indicated that a bimodal curve was found in the volume and surface area distribution of grain starch granules, and a unimodal curve was observed for the number distribution under all treatments. The exogenous ABA resulted in a significant increase in the proportions （both by volume and by surface area） of B-type （<9.9 μm in diameter） starch granules, with a reduction in those of A-type （>9.9 μm） starch granules, while, the exogenous GA₃ led to converse effects on size distribution of those starch granules. The exogenous ABA also increased starch, amylose and amylopectin contents at maturity but significantly reduced the ratio of amylose to amylopectin. Application of GA₃ significantly reduced starch content, amylopectin content but increased the ratio of amylose to amylopectin. The ratio of amylose to amylopectin showed a significant and negative relationship with the volume proportion of granules <9.9 μm, but was positively related to the volume proportion of granules 22.8-42.8 μm.  相似文献   

Licochalcone A prevents adipocyte differentiation and lipogenesis via suppression of peroxisome proliferator-activated receptor γ and sterol regulatory element-binding protein pathways     

Quan HY  Baek NI  Chung SH 《Journal of agricultural and food chemistry》2012,60(20):5112-5120

Licochalcone A (LA) has been shown to exert multiple pharmacological effects, including anti-inflammatory, antiparasitic, antifungal, anticancer, and osteogenic activities. The present study investigated the ability of LA to suppress the differentiation of 3T3-L1 preadipocytes, and its antiobesity activity was explored using high fat diet (HFD)-fed ICR mice. During the terminal differentiation process, 3T3-L1 preadipocytes were treated with LA, and the lipid contents were quantified along with any changes in the expression of biomarkers associated with adipocyte differentiation and lipogenesis. The results show that LA significantly reduced lipid accumulation and down-regulated the expression of peroxisome proliferator-activated receptor γ, CCAAT/enhancer binding protein α, sterol regulatory element-binding protein 1c, and their target genes (fatty acid binding protein, fatty acid synthase, stearoyl-CoA desaturase 1, and glycerol-3-phosphate acyltransferase). In an animal study, body weight, triglyceride, cholesterol, and nonesterified fatty acid levels in the group given 10 mg/kg LA were significantly decreased by 14.0, 48.2, 58.9, and 73.5%, respectively. Transverse microcomputed tomography indicated that visceral fat depots in LA-treated mice were markedly reduced when compared with those of the HFD control group. In summary, these results suggest that LA exerts an antiobesity effect and that it is a candidate for future clinical trials.  相似文献   

Enzymatic Synthesis of Piceid Glucosides Using Maltosyltransferase from Caldicellulosiruptor bescii DSM 6725     

H Park  J Kim  KH Choi  S Hwang  SJ Yang  NI Baek  J Cha 《Journal of agricultural and food chemistry》2012,60(33):8183-8189

Piceid is widely used in food, cosmetics, and pharmaceuticals because of its therapeutic benefits. However, the use of piceid as a drug is limited because of its low solubility. To increase solubility, we synthesized piceid glucosides using maltosyltransferase from Caldicellulosiruptor bescii . The MTase gene was cloned and expressed in Escherichia coli . The enzyme had a unique transfer specificity to the transfer of maltosyl units. Four piceid transglycosylation products were present and identified by thin-layer chromatography and recycling preparative high-performance liquid chromatography. The major product was purified by C(18) and gel filtration chromatography, and its molecular structure was determined using nuclear magnetic resonance spectroscopy to be α-d-maltosyl-(1→4)-piceid. The solubility of maltosyl piceid was 8.54 × 10(3) and 1.86 × 10(3) times those of natural resveratrol and piceid, respectively, suggesting that the transglycosylation greatly increased the water solubility. This suggests that dietary intake of this compound can enhance the bioavailability of resveratrol in the human body.  相似文献   

Does involvement in food preparation track from adolescence to young adulthood and is it associated with better dietary quality? Findings from a 10-year longitudinal study     

Laska MN  Larson NI  Neumark-Sztainer D  Story M 《Public health nutrition》2012,15(7):1150-1158

  相似文献   

大学计算机基础分级教学模式探讨   总被引：1，自引：0，他引：1  

蒋兰玲  张爱国  宋平 《高等农业教育》2011,(9):53-55

分析了在大学计算机基础课程教学中应用分级教学模式的理论和现实依据,提出了采用摸底测试与学生意愿相结合的方式进行计算机基础课的分级教学,探讨了分级教学模式的分级手段、教学方案、成绩评定方式改革等相关问题。  相似文献