Comment on "Failure of bone marrow cells to transdifferentiate into neural cells in vivo"     

Mezey E  Nagy A  Szalayova I  Key S  Bratincsak A  Baffi J  Shahar T 《Science (New York, N.Y.)》2003,299(5610):1184; author reply 1184

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Hydrogen-Bond Breaking and Proton Exchange in Collisions of Gaseous Formic Acid with Liquid Sulfuric Acid     

JK Klassen  GM Nathanson 《Science (New York, N.Y.)》1996,273(5273):333-335

Gas-liquid scattering experiments provide direct observations of the fate of hydrogen-bonding molecules striking the surfaces of acidic liquids. Collisions of gaseous formic acid with concentrated sulfuric acid show that impinging monomers (HCOOH and DCOOD) scatter inelastically from the interface or become trapped by surface H2SO4. Most trapped DCOOD molecules undergo proton exchange before desorbing from the acid, indicating that gas-surface accommodation almost always leads to reaction with H2SO4 molecules. This proton transfer is not inhibited by dimerization of the formic acid: The dimers readily undergo intramolecular hydrogen bond cleavage and D-H exchange before desorbing from the acid.  相似文献   

Replicon typing of F18 fimbriae encoding plasmids of enterotoxigenic and verotoxigenic Escherichia coli strains from porcine postweaning diarrhoea and oedema disease   总被引：10，自引：0，他引：10  

Fekete PZ  Gerardin J  Jacquemin E  Mainil JG  Nagy B 《Veterinary microbiology》2002,85(3):275-284

The presence of fimbrial adhesin F18 is frequently found in enterotoxigenic Escherichia coli (ETEC) and verotoxigenic E. coli (VTEC) strains responsible for diarrhoea and oedema disease of weaned pigs. The F18 adhesin occurs in two antigenic variants: F18ab is characteristic of VTEC while F18ac is more typical for ETEC. F18 encoding plasmids of 17 phenotypically characterized porcine E. coli isolates (10 ETEC, 6 VTEC and 1 ETEC/VTEC) were tested with a DNA probe for F18 fimbrial adhesin and with replicon probes for the RepFIa, RepFIb and for the RepFIc family of basic replicons. In all the cases, the F18 probe hybridized to only one plasmid band of size higher than 42MDa. All F18 plasmids were determined to be unireplicon plasmids belonging to the RepFIc replicon family of the F incompatibility complex. There was no difference between F18ac plasmids of ETEC and F18ab plasmids of VTEC strains in terms of replicon type or subtype. However, the size of F18ab plasmids of the VTEC strains varied between 42 and 98MDa, in contrast to F18ac plasmids of ETEC strains (constantly approximately 98MDa).  相似文献   

Resuscitation and Critical Care of Neonatal Calves     

Dusty W. Nagy 《Veterinary Clinics of North America: Food Animal Practice》2009

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Evaluation of porcine reproductive and respiratory syndrome virus replication in laboratory rodents     

Paul Rosenfeld  Patricia V. Turner  Janet I. MacInnes  éva Nagy  Dongwan Yoo 《Canadian journal of veterinary research》2009,73(4):313-318

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Some changes to the CJVR          下载免费PDF全文

′Eva Nagy 《Canadian journal of veterinary research》2000,64(1):1

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Veterinary Microbiology.: D.C. Hirsh, Y.C. Zee (Eds.); Malden, Massachusetts, 1999, 479 pp., price US$ 69.95, ISBN 0-86542-543-4     

C. L. Gyles  E. Nagy 《Veterinary microbiology》1999,70(3-4):277-279

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Enterotoxigenic Escherichia coli (ETEC) in farm animals.   总被引：11，自引：0，他引：11  

B Nagy  P Z Fekete 《Veterinary research》1999,30(2-3):259-284

Animal diseases due to enterotoxigenic Escherichia coli (ETEC) typically appear as severe watery diarrhoea during the first few days of life (also a few days after weaning in pigs). ETEC adhere to the small intestinal microvilli without inducing morphological lesions and produce enterotoxins acting locally on enterocytes. This action results in the hypersecretion (of water and electrolytes) and reduced absorption. Adhesins and toxins are the two prominent virulence attributes of ETEC and the level of knowledge of these factors determines the chances for successful prevention and therapy of the disease. For animal ETEC the most common adhesins are the fimbriae (pili) on the surface: F4(K88), F5(K99), F6(987P), F41, F42, F165, F17 and F18. Enterotoxins (extracellular proteins or peptides) of animal ETEC are classified as heat-labile (LT) and heat-stable (ST) enterotoxins with further subdivisions (LTh-I, LTp-I, LTIIa, LTIIb, STaH, STaP, STb) according to antigenic and biological differences. Fimbriae and LT enterotoxins are made up of large molecular weight proteins which facilitate their utilisation in vaccines and their detection using immunodiagnostic systems. The adhesive fimbriae and enterotoxins of animal ETEC are plasmid determined (except F41 and F17). Virulence gene probes (DNA hybridisation, PCR) are specific and sensitive diagnostic and epidemiologic tools for the detection of ETEC. Based on genetic typing, the ETEC, in spite of limited serogroups, seem to represent a population of E. coli with a diverse genetic background.  相似文献   

Design and fabrication of topologically complex, three-dimensional microstructures     

RJ Jackman  ST Brittain  A Adams  MG Prentiss  GM Whitesides 《Science (New York, N.Y.)》1998,280(5372):2089-2091

Two concepts for use in the fabrication of three-dimensional (3D) microstructures with complex topologies are described. Both routes begin with a two-dimensional (2D) pattern and transform it into a 3D microstructure. The concepts are illustrated by use of soft lithographic techniques to transfer 2D patterns to cylindrical (pseudo-3D) substrates. Subsequent steps-application of uniaxial strain, connection of patterns on intersecting surfaces-transform these patterns into free-standing, 3D, noncylindrically symmetrical microstructures. Microelectrodeposition provides an additive method that strengthens thin metal designs produced by patterning, welds nonconnected structures, and enables the high-strain deformations required in one method to be carried out successfully.  相似文献   

Viral haemorrhagic septicaemia virus IVb experimental infection of rainbow trout,Oncorhynchus mykiss (Walbaum), and fathead minnow,Pimphales promelas (Rafinesque)     

L Al‐Hussinee  P Huber  S Russell  V LePage  A Reid  K M Young  E Nagy  R M W Stevenson  J S Lumsden 《Journal of fish diseases》2010,33(4):347-360

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