In late November 1991, 1883 clinics in Canada were sent a questionnaire to assess the status of Dirofilaria immitis in dogs in 1991 and there was a 60.0% response. There were 344,031 dogs tested for heart-worm (HW), 627 were found infected and the prevalence of HW infection was 0.18%. There were 417 dogs with HW in Ontario, 116 in Manitoba, 38 in Quebec, 53 in British Columbia, three in Alberta, and one in Nova Scotia. In British Columbia, all of the infected dogs but one were from the Okanagan valley which, as from 1991, is a new focus of infection in Canada. Most dogs with HW had not been on preventive medication in 1990, and the prevalence among dogs tested and unprotected was 0.59%. That prevalence was considerably higher in endemic areas. Companion dogs, over three years of age and maintained primarily outdoors in rural areas, were most frequently infected. One cat was diagnosed with D. immitis and 33 dogs had Dipetalonema reconditium.相似文献
The pharmacokinetics of thiamphenicol were studied after intravenous and intramuscular administration of 25 mg/kg body weight in lactating cows. Distribution (t1/2) and elimination (t1/2) half-lives of 6.10±1.39 min and 1.60±0.30 h, respectively, were obtained after intravenous administration. The body clearance was 3.9±0.077 ml/kg per min and the apparent volume of distribution was 1220.79±256.67 ml/kg. The rate at which thiamphenicol appeared in the milk, as indicated by the penetration half-life (t1/2P) (serum to quarters), was found to be 36.89±11.14 min. The equivalent elimination half-life (t1/2E) (quarters to serum) from the milk was 3.62±1.06 h and the peak thiamphenicol concentration in the milk was 23.09±3.42 µg/ml at 2.5±0.32 h.After intramuscular injection, the elimination half-life was 2.2±0.40 h, the absorption half-life was 4.02±1.72 min and the peak concentration in the serum was 30.90±5.24 µg/ml at 23±8.4 min. The bioavailability after intramuscular administration approached 100%. The penetration half-life was 50.59±6.87 min, the elimination half-life was 5.91±4.97 h and the mean peak concentration in the milk was 17.37±2.20 µg/ml at 3.4±0.22 h.Abbreviations AUC
area under the concentration-time curve
- CAP
chloramphenicol
-
Cmax
peak concentration
- IM
intramuscular
- IV
intravenous
- TAP
thiamphenicol
-
t1/2
distribution half-life
-
t1/2
elimination half-life
-
Vc
volume of central compartment
-
Vd
volume of distribution 相似文献
This paper deals with a study on the effects of mixtures of partially resistant cultivars in focus forming plant diseases.
The focus expansion velocity in a mixture of two partially resistant cultivars depends on four parameters, the focus expansion
velocity in a crop of cultivar 1 only and in a crop of cultivar 2 only, the net-reproduction in a crop of cultivar 1 and of
cultivar 2, respectively.
An explicit equation is developed for the damage of a cultivar mixture where the crop is infected by two physiological races
of the pathogen. It is shown that cultivar mixtures exist where damage is smaller than in crops of either of the two cultivars
only. A simple explicit formula is given on the basis of which it can be decided whether an optimal mixture exists for a given
pathosystem. 相似文献
Summary The segregation of RFLP and RAPD markers was compared in two oilseed rape (Brassica napus L.) breeding populations from the cross Topas x R4, the latter being a low linolenic mutation line. A total progeny of 68 F2 and 40 microspore derived plants were studied with 25 markers. The results indicated a significant excess of Topas alleles at five RAPD loci in the microspore derived population. This suggests that genomic regions which probably affect microspore culture ability do not have identical distribution in the two population types. 相似文献
1. The parameters used for the mechanics of standing in birds are defined and compared for two strains of turkeys, a giant, broad‐breasted strain (up to 40 kg), the result of artificial selection, and a traditional, smaller bird (9 kg), in order to show whether the mechanics of standing are modified by selection.
2. Using a geometrical similarity hypothesis, it was found that, although the locomotor apparatus of both strains are similar, the stresses on the pelvic muscles of broad‐breasted turkeys are increased. This is induced by the anterior position of the centres of gravity of their trunks, the result of selected pectoral hypertrophy.
3. The modification to the mechanics of standing may be related to the increase in locomotor disease in strains of giant turkeys. 相似文献
1. Ileal endogenous amino acid losses were determined in broiler chickens and in cannulated cross‐bred layer strain cockerels using either a nitrogen‐free diet, regression analysis or a 48 h fast.
2. Endogenous amino acid flows to the ileum in fasted cockerels were significantly lower than those obtained both by feeding the nitrogen‐free diet, and from regression analysis in either broilers or cockerels. Regression analysis gave the highest flows.
3. The apparent digestibility coefficients of amino acids in a diet containing 200 g/kg crude protein were lower in broilers (0.84) than in cockerels (0.88). When corrected, by regression analysis, for the contribution of endogenous amino acids, the true digestibility coefficients became 0.90 and 0.92 respectively. 相似文献
1. An experiment was designed to test the response of broiler chicks (0–21 d) to dietary lysine concentration. Concentrations ranged from 9.9 to 14.4 g of lysine per kg diet when energy was 13.4 MJ ME/kg.
2. Estimates of the concentration of lysine needed for maximum body weights gain, food consumption and gain:food ratio were calculated using two statistical methods. An average of these estimates was 12.0 g lysine/kg diet to 21 d of age.
3. Chicks given 13.9 or 14.4 g lysine/kg diet were negatively affected by these concentrations. The decreases in average weight gain, food consumption and food efficiency were caused mainly by several chicks that developed severe leg problems and were much smaller than their pen mates. Chicks with no leg problems gained weight as rapidly as chicks receiving optimal amounts of lysine. 相似文献
