Clock mutation affects circadian regulation of circulating blood cells   总被引：1，自引：0，他引：1  

Katsutaka Oishi  Naoki Ohkura  Koji Kadota  Manami Kasamatsu  Kentaro Shibusawa  Juzo Matsuda  Kazuhiko Machida  Shuichi Horie  Norio Ishida 《Journal of circadian rhythms》2006,4(1):13-7

Background  

Although the number of circulating immune cells is subject to high-amplitude circadian rhythms, the underlying mechanisms are not fully understood.  相似文献   

Studies on the organo-mineral colloidal complexes of paddy soil II     

Hidenori Hashimoto  Togoro Harada  Toshinobu Yumoto 《Soil Science and Plant Nutrition》2013,59(3):110-116

In the preceding paper (1) the authors reported the humus status in the organo-mineral colloidal complexes of the degraded paddy soils, which is characterized by the leaching of active iron, manganese and the other elements such as silica, magnesium and phosphoric acid from the furrow slice (2). And it was concluded that the organo-mineral colloidal complexes (Gl colloidal complexes) of the degraded paddy soil is characterized by the marked accumulation of humus, especially the readily soluble humus as compared with those of the normal.  相似文献   

Distribution of new methylene blue injected into the lumbosacral epidural space in cats     

Lee I  Yamagishi N  Oboshi K  Yamada H 《Veterinary anaesthesia and analgesia》2004,31(3):190-194

OBJECTIVE: To determine the effects of injection volume and vertebral anatomy on the spread of new methylene blue (NMB) injected into the lumbosacral epidural space in cats. STUDY DESIGN: Prospective experimental study. SAMPLE POPULATION: Sixteen cats. METHODS: Cats were randomly assigned to four groups and received from 0.1 to 0.4 mL kg(-1) of 0.12% NMB in 0.9% saline. Injection was made into the lumbosacral epidural space using a dorsal approach with the cats in sternal recumbency. The extent of cranial migration of the dye as indicated by the staining of epidural fat and dura mater was measured. RESULTS: The mean +/- SD (range) number of stained vertebrae in the 0.3 and 0.4 mL kg(-1) groups, were 11.5 +/- 1.5 (T7-T11) and 12.4 +/- 1.8 (T6-T10), respectively. This was significantly greater than the number in the 0.1 and 0.2 mL kg(-1) groups, 4.3 +/- 0.6 (L3-L4) and 6.0 +/- 0.7 (L1-L2) vertebrae, respectively (p < 0.001). Linear regression analysis showed that the volume injected correlated significantly with the number of stained vertebrae (R2 = 0.83, p < 0.001). In the dorsal and lateral aspect of the spinal cord, NMB solution distributed between epidural fat and dura mater. Migration under the spinal cord occurred along the two longitudinal epidural veins. CONCLUSIONS AND CLINICAL RELEVANCE: The larger the volume of solution injected into the lumbosacral epidural space in cats, the greater the spread.  相似文献   

Eliminating the effect of epidural fat during dorsolumbar epidural analgesia in cattle     

Lee I  Yamagishi N  Oboshi K  Yamada H 《Veterinary anaesthesia and analgesia》2004,31(2):86-89

Objective To compare the distribution of new methylene blue (NMB) solution injected into either the subperiosteal space or under the epidural fat at the first and second lumbar vertebral interspace in cattle. Study design Prospective experimental study. Sample population Nine nonpregnant cows. Methods Needles were advanced towards the first interlumbar epidural space using a dorsal mid‐line approach. Upon confirmation of successful penetration of the ligamentum flavum, group 1 received 5 mL of 0.12% NMB in 0.9% saline. In group 2, the needle was slowly advanced a further 7–10 mm to ensure injection under the epidural fat; the same dose was injected. The extent of cranial and caudal migration of dye, as indicated by staining of epidural fat and the dura mater was measured. Results In group 1 (n = 4), NMB solution migrated only between the periosteum and the epidural fat. There was unilateral distribution in two cows. In contrast, there was no difference between left‐ and right‐sided distribution in group 2 (n = 5), and the NMB solution migrated only between epidural fat and the dura mater. Although the dura mater was not penetrated in any animal of group 2, the dorsal roots were slightly stained and the overlying dura mater was heavily stained in these animals. Conclusions and clinical relevance Variation in distribution of local anaesthetic solution can probably be overcome by deeper needle penetration of the epidural fat.  相似文献   

Comparative analysis of the inverted repeat of a chalcone synthase pseudogene between yellow soybean and seed coat pigmented mutants     

Mineo Senda  Satsuki Nishimura  Atsushi Kasai  Setsuzo Yumoto  Yoshitake Takada  Yoshinori Tanaka  Shizen Ohnishi  Tomohisa Kuroda 《Breeding Science》2013,63(4):384-392

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Effects of Treatment for Anestrus in Water Buffaloes with PGF2α and GnRH in Comparison with Vitamin-Mineral Supplement,and Some Factors Influencing Treatment Effects     

Bhuminand DEVKOTA  Toshihiko NAKAO  Kosaku KOBAYASHI  Hiroshi SATO  Shyam Kishor SAH  Dinesh Kumar SINGH  Ishwori Prasad DHAKAL  Norio YAMAGISHI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2013,75(12):1623-1627

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Screening of cultivated and wild adzuki bean for resistance to race 3 of <Emphasis Type="Italic">Cadophora gregata</Emphasis> f. sp. <Emphasis Type="Italic">adzukicola</Emphasis>, cause of brown stem rot     

Norio Kondo  Hisanori Shimada  Shohei Fujita 《Journal of General Plant Pathology》2009,75(3):181-187

Two diseases of adzuki bean, brown stem rot (BSR, caused by Cadophora gregata f. sp. adzukicola) and adzuki bean Fusarium wilt (AFW, caused by Fusarium oxysporum f. sp. adzukicola), are serious problems in Hokkaido and have been controlled using cultivars with multiple resistance. However, because a new race of BSR, designated race 3, was identified, sources of parental adzuki bean for resistance to race 3 were needed. Therefore, we examined 67 cultivars and lines of cultivated and wild adzuki bean maintained at the Tokachi Agricultural Experiment Station using a root-dip inoculation method. Consequently, nine adzuki bean cultivars, one wild adzuki bean accession and 30 lines (including two lines resistant to all the three races of BSR and AFW) were confirmed to be resistant or tolerant to race 3 of BSR, and we found a cultivar Akamame as well as a wild adzuki bean Acc2515 to be a new source for a resistance gene to the race 3. This cultivar also holds promise as a source of resistance against other races of BSR and AFW.  相似文献   

The first occurrence of leaf mold of tomato caused by races 4.9 and 4.9.11 of <Emphasis Type="Italic">Passalora fulva</Emphasis> (syn. <Emphasis Type="Italic">Fulvia fulva</Emphasis>) in Japan     

Junichiro Enya  Kentaro Ikeda  Taeko Takeuchi  Norio Horikoshi  Takahiko Higashi  Takako Sakai  Yuichiro Iida  Kazufumi Nishi  Masaharu Kubota 《Journal of General Plant Pathology》2009,75(1):76-79

Tomato leaf mold caused by Passalora fulva was found on two tomato varieties carrying the Cf-9 gene in Japan, in 2007. The isolates obtained from Chiba and Fukushima were identified as race 4.9.11, and those from Gunma were races 4.9 or 4.9.11. This is the first report in Japan of tomato leaf mold caused by P. fulva strains that can overcome the Cf-9 gene.  相似文献   

Hydrolysis kinetic parameters of DP 6, 7, 8, and 9-12 fructooligosaccharides (FOS) of onion bulb tissues. effect of temperature and storage time     

Benkeblia N  Shiomi N 《Journal of agricultural and food chemistry》2006,54(7):2587-2592

The objective of this study was to report on the variation of DP 6 isomers (6b, 6c + 6d1 + 6d2), 7a, 8, and 9-12 fructooligosaccharides (FOS) and their hydrolysis parameters [percent hydrolysis, consumption rate, hydrolysis rate constant (k(obsd)), and half-life time (t(1/2))] in onion bulb tissues stored for 6 months at 10, 15, or 20 degrees C. The hydrolysis of DP 6 isomers, 7a, and 8 ranged from 74 to 85%, whereas that of DP 9-12 averaged 86%. The consumption rate of 6b, 6c + 6d1 + 6d2, 7a, 8, and -12 averaged 25, 58, 38, 26, and 48 microg/g of fresh weight per week, respectively. The k(obsd) showed large variation from 53 x 10(-3) week(-1) (lowest value) to 92 x 10(-3) week(-1) (highest value), whereas the half-life t(1/2) of the different FOS ranged between 7.5 and 13.1 weeks. DP 6b isomers increased during the first month, and then the content decreased sharply during the second month at 20 degrees C but remained stable during the last 4 months, whereas at 10 and 15 degrees C, 6b decreased progressively from the first to the six month. In contrast, DP 6c + 6d1 + 6d2 decreased abruptly within the first 3 months at 10, 15, and 20 degrees C; however, during the last 3 months they remained stable, ranging between 0.32 and 0.39. Variation of DP 7a, 8, and 9-12 FOS was close to that of DP 6 FOS isomers. DP 7a increased slightly during the first month, and afterward 7a started decreasing progressively during the last 5 months. DP 8 FOS showed a similar pattern independent of temperature regime: they increased slightly within the first month, but from the second month, DP 8 began decreasing progressively and continued decreasing to the sixth month. DP 9-12 FOS also varied similarly to DP 6c + 6d1 + 6d2. They decreased sharply within the first 2 months, and during the last 4 months, they continued to decrease slowly. Surprisingly, these variations occurred independently of temperature regimes and were affected only by storage duration. It was concluded that highly polymerized FOS are preferably hydrolyzed rather than low DP FOS isomers because they have a relatively high content of fructosyl end chains.  相似文献   

Colorimetric assay for the quantification of serum iodixanol concentration and its application on estimation of glomerular filtration rate in cattle     

Miura M  Yamagishi N  Sasaki K  Kim D  Devkota B  Furuhama K 《Research in veterinary science》2012,93(1):378-380

A colorimetric assay used to quantify the non-ionic contrast medium iodixanol in sera was validated and compared with high-performance liquid chromatography. The application of this assay to estimate glomerular filtration rates (GFR) in cattle was examined. Serum iodixanol was de-iodinated by alkaline hydrolysis and the amount of released iodine was subsequently determined using a ceric arsenite method. There was a close correlation between the two methods using identical specimens. In clinically healthy cattle with different body weights, the reference value (166.3-178.8 mL/min/m(2)) based on body surface area was fairly stable as compared with that (2.13-3.63 mL/min/kg) based on body weight. Based on GFR data in healthy and renal-impaired cattle, when the GFR decreased to more than 60% of the reference value, serum urea nitrogen and creatinine concentrations increased. The colorimetric assay is a simple method for the estimation of GFR in cattle and requires no expensive equipment.  相似文献