Adverse Drug Reactions: Report of the Australian Veterinary Association Adverse Drug Reaction Subcommittee, 1993     

JE MADDISON 《Australian veterinary journal》1994,71(2):53-57

SUMMARY Fifty-nine reports of suspected adverse drug reactions (ADRs) were received by the Adverse Drug Reaction Subcommittee of the Australian Veterinary Association from April 1992–March 1993 inclusive. The number of reports received/number of animals involved per species was: dogs (30/43); cats (11/14); horses (8/10); cattle (9/30); ferret (1/1). Of these, 37 (63%) were classified as definite ADRs and 12 (20%) as probable ADRs. In 10 (17%) reports an ADR could not be substantiated or there was insufficient information available to make a decision. Twenty-three reports involved apparent hypersensitivity reactions and 5 reports were associated with ‘off-label’ use. Of the definite and probable reports of suspect ADRs the most frequent types of drugs involved were antimicrobials (9 reports), anthelmintics (9 reports), vaccines (7 reports), insecticides (6 reports), vitamin preparations (6 reports), topical anti-inflammatory/antimicrobial/antifungal skin preparations (3 reports) and nonsteroidal anti-inflammatory preparations (3 reports). Single reports concerning definite or probable ADRs to an anticholinergic, an anaesthetic agent, a corticosteroid, an anabolic steroid and a chondroprotective drug were received.  相似文献   

OC5
Filtration Thought Sephadex Columns Does not Alter the Subpopulation Characteristics in Fresh Boar Semen     

L Rami‐Lluch  M Rivera  T Rigau  S Balasch  JE Rodríguez‐Gil 《Reproduction in domestic animals》2006,41(Z2):104-104

The aim of this study was to analyse the effect of filtration through Sephadex on the subpopulation characteristics of the boar semen. For this purpose 3 ml of 16 commercial doses of fresh diluted boar semen were filtered through a Sephadex G‐15/Polypropylene column. Motility parameters were analysed by a CASA system and statistical study was performed by SAS package using the VARCLUS and the FASTLUST procedures. Statistical study revealed four subpopulations in fresh boar semen, as previously had described (Theriogenology 61: 673–690).Total motility was higher in control than in filtered semen, but there were not statistical differences (65.63 ± 9.65 vs 41.40 ± 9.02). Moreover, the analysis did not show many changes neither in the characteristics nor in the distribution of the four subpopulations. As example although ALHmed of filtered samples were slightly higher, there were only significant differences (p < 0.001) in two subpopulations (subpopulation 2 : 2.2 ± 0.05 in control vs 2.7 ± 0.08 in filtered. Subpopulation 3 : 4.5 ± 0.11 in control vs 5.8 ± 0.23 in filtered semen). HME was also statistically different (p < 0.005) in one subpopulation, showing great values in filtered semen (1.7 ± 0.15 vs 3.0 ± 0.30). In conclusion, the filtration by Sephadex/Polypropylene column does not cause strong changes in subpopulation sperm distribution.  相似文献   

Production responses of steers to growth promotant implants designed for heifers     

Yockney ND  Van der Oord K 《New Zealand veterinary journal》1989,37(3):128-129

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Blindness in goats following ingestion of Stypandra glauca     

RJ WHITTINGTON †  JE SEARSON  SJ WHITTAKER‡  JRW GLASTONBURY 《Australian veterinary journal》1988,65(6):176-181

Twenty-seven of 427 Angora goats of mixed age became blind within a week of consuming large amounts of Stypandra glauca ("nodding blue lily"). A further 200 goats were depressed for several weeks, but most subsequently recovered. Blindness was associated with optic nerve neuropathy which is postulated to have followed compression of the optic nerves within the bony optic canals as a result of severe myelin oedema. Histologically, the intracanalicular portion of the optic nerve was sclerotic, while the intracranial portion of the optic nerve and the optic tracts were degenerating. The retrobulbar portion of the optic nerve was relatively unaffected. In addition, multifocal retinal photoreceptor degeneration was found ophthalmoscopically and histologically. The syndrome was not reproduced during a trial in which 2 goats were fed 4 and 20 kg of S. glauca harvested after it had finished flowering, more than 3 weeks after the first natural cases of blindness. Based on epidemiological and pathological data we propose that S. glauca is toxic to stock, but only for a short period while flowering in spring.  相似文献   

Effects of Constant, 9 and 16-h Light Cycles on Sperm Quality, Semen Storage Ability and Motile Sperm Subpopulations Structure of Boar Semen     

MM Rivera  A Quintero-Moreno  X Barrera  T Rigau  JE Rodríguez-Gil 《Reproduction in domestic animals》2006,41(5):386-393

This study was performed to test the effect that two separate, daily, constant-light regimes of both 9 and 16 h could have on the main parameters of boar-semen quality analysis, as well as on the motile sperm subpopulations structure and the ability of its conservation at 16 degrees C. Results show that both luminous regimes have slight, specific effects on the main parameters of boar-semen quality analysis, as well as on the motile sperm subpopulations structure. Furthermore, the conservation ability at 16 degrees C of boar semen was not significantly different between both photoperiods. When a temporal study was performed, results showed that semen quality and motility parameter changes were stabilized at nearly constant values from the second month of the study to the last month in both luminous regimes, indicating a rapid light-related effect on testicular function. Our results indicate that light regimes oscillating from 9 h daily to 16 h daily are of little importance in the control of boar-semen quality in a farming environment.  相似文献   

Factors affecting the relationship between arterial and end-tidal carbon dioxide pressures in the anaesthetised horse     

JE Rainger  CM Dart  NR Perkins 《Australian veterinary journal》2010,88(1-2):13-19

Objective To assess the effects of the duration of anaesthesia, position of recumbency, mode of ventilation, anaesthetic drug protocol, patient age and type of surgical procedure on the usefulness of capnometry as a measure of the partial pressure of arterial carbon dioxide (P_aco ₂) during general anaesthesia in horses. Design A prospective study compared the P_aco ₂ values with those of partial pressure of end-tidal carbon dioxide (ETco ₂) in horses anaesthetised for elective or emergency surgical procedures. The difference between P_aco ₂ and ETco ₂ (P_aco ₂− ETco ₂) and the physiological dead space to tidal volume ratio (V_D/V_T) were calculated. The effects of the study parameters on these variables was determined. Results The agreement between P_aco ₂ and ETco ₂ was poor. P_aco ₂− ETco ₂ and V_D/V_T during the first 60 min of anaesthesia was significantly less than after 60 min of anaesthesia. Mode of ventilation, position of recumbency, anaesthetic drug protocol, patient age and type of procedure did not have a significant affect on either value. Conclusions P_aco ₂− ETco ₂ in anaesthetised horses can be large, making ETco ₂ unreliable as a predictor of P_aco ₂ and for assessment of pulmonary ventilation. For anaesthesia lasting less than 60 min at least one blood gas analysis of an arterial blood sample is required to assess P_aco ₂− ETco ₂. Arterial blood gas analysis should be repeated after 60 min of general anaesthesia.  相似文献   

Effects of leaf N concentration and leaf area index on determining rice tillering Chinese Rice Research Newsletter     

ZHONG Xuhua  PENG Shaobing  SHEEHY JE  LIU Hongxian 《水稻科学》1999,7(4):8

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Case series of equine pituitary pars intermedia dysfunction in a tropical climate     

CW Spelta  JE Axon 《Australian veterinary journal》2012,90(11):451-456

The clinical manifestations of equine pituitary pars intermedia dysfunction (PPID) in temperate climates are well described. The classic presentation is that of an older animal with hirsutism, laminitis, poor muscle tone, pendulous abdomen and weight loss. This case series highlights the additional clinical signs of anhidrosis and heat stress with secondary exercise intolerance that were seen as primary presenting problems in equids with PPID in the hot, humid conditions of a tropical climate. The clinical signs resolved with medical treatment for PPID.  相似文献   

Diagnosis,treatment and outcomes for koala chlamydiosis at a rehabilitation facility (1995–2005)     

JE Griffith  DP Higgins 《Australian veterinary journal》2012,90(11):457-463

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Pregnancy diagnosis in the dog: A comparison between abdominal palpation and linear‐array real‐time echography     

M. A. M. Taverne  A. C. Okkens  R. van Oord 《The Veterinary quarterly》2013,33(4):249-255

Summary

This paper presents quantitative results of canine pregnancy diagnoses performed by abdominal palpation and/or linear‐array real‐time echography.

Each animal was first palpated by an experienced clinician and then another investigator performed ultrasound scanning using a 3 MHz transducer. In other dogs echography was undertaken only when the result of abdominal palpation was negative or doubtful or when the owner requested ultrasound scanning. Using all tests performed between days 20 and 49 of pregnancy (day 0 = day of first mating or insemination), the results of abdominal palpation (n= 116) versus real‐time scanning (n = 135) were: sensitivity: 89.0% v 92.9%; specificity: 93% v 96.0%; positive predictive value: 95.6% v 97.5%; negative predictive value: 83.3% v 88.9%. Results of ultrasound tests performed in 97 other dogs were: sensitivity: 92.4%; specificity: 97.7%; positive predictive value: 98.0% and negative predictive value: 91.4%. Almost identical figures were found when only the tests performed between days 25 and 35 of pregnancy were included.

It was concluded that 1) real‐time ultrasound scanning is an accurate method for discriminating between pregnant and non‐pregnant bitches; 2) sensitivity and specificity of the abdominal palpation technique executed by an experienced clinician approach that of ultrasound scanning; 3) small litter size and lack of knowledge of conception date are the main sources of false negative diagnoses.  相似文献