Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite   总被引：1，自引：0，他引：1  

Platten M  Ho PP  Youssef S  Fontoura P  Garren H  Hur EM  Gupta R  Lee LY  Kidd BA  Robinson WH  Sobel RA  Selley ML  Steinman L 《Science (New York, N.Y.)》2005,310(5749):850-855

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Veterinary public health in a problem-based learning curriculum at the Western University of Health Sciences     

Schmidt PL  Trevejo RT  Tkalcic S 《Journal of veterinary medical education》2008,35(2):212-218

As detailed in the Association of Schools of Public Health / Association of American Veterinary Medical Colleges 2007 Joint Symposium on Veterinary Public Health, veterinary public health (VPH) can no longer be viewed as a unique sub-specialty of veterinary medicine. Rather, its practice pervades nearly every aspect of the veterinary profession, regardless of whether the practitioner is engaged in small-animal, large-animal, research, corporate, or military practice. In congruence with the practice of VPH, the teaching of VPH should also pervade nearly every aspect of veterinary education. Accordingly, at Western University of Health Sciences, College of Veterinary Medicine (WU-CVM), public health is not simply taught as an individual course but, rather, is interwoven into almost every aspect of the curriculum, continually emphasizing the relevance of this discipline to the practice of veterinary medicine. This article outlines the teaching philosophy of WU-CVM, provides an overview of the curriculum, and describes the integral nature of public health throughout all four years of the educational program.  相似文献   

Potential pathogens in feces from unweaned llamas and alpacas with diarrhea     

Cebra CK  Mattson DE  Baker RJ  Sonn RJ  Dearing PL 《Journal of the American Veterinary Medical Association》2003,223(12):1806-1808

OBJECTIVE: To identify potential pathogens in feces from llama and alpaca crias with diarrhea. DESIGN: Prospective observational study. ANIMALS: 45 unweaned crias with diarrhea. PROCEDURE: Fecal samples were evaluated for Eimeria spp, Giardia spp, Cryptosporidium spp, enteric viruses, and Salmonella spp. A questionnaire yielded information concerning herd management and presence of other affected camelids. RESULTS: 28 crias were < or = 31 days old, 11 were 32 to 62 days old, and 6 were 63 to 210 days old. Potential pathogens were isolated from feces from 32 of the 45 crias. A total of 39 potential pathogens were obtained, including coronavirus (n = 19 crias; 42%), Giardia spp (8; 18%), Eimeria spp (6; 13%), Cryptosporidium spp (4; 9%), rotavirus (1; 2%), and nematode ova (1; 2%). Salmonella spp were not isolated. Most crias from which potential pathogens were isolated were identified during outbreaks of diarrhea involving other camelids, although only coronavirus was isolated from crias identified during outbreaks involving adult camelids. Coronavirus was detected throughout the year, whereas protozoa were most commonly isolated during the fall and winter. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that a variety of potential pathogens may be isolated from young crias with diarrhea. Many crias shed coronavirus, which may also have been affecting older camelids. Protozoa were isolated most often during wetter months, suggesting that crias born during these months may have greater exposure to protozoal pathogens.  相似文献   

Public health. Arsenic epidemiology and drinking water standards     

Smith AH  Lopipero PA  Bates MN  Steinmaus CM 《Science (New York, N.Y.)》2002,296(5576):2145-2146

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Morphological and reproductive characterization of nascent allotetraploids cross-compatible with cultivated peanut (Arachis hypogaea L.)     

Levinson  Chandler  Chu  Ye  Luo  Xuelin  Stalker  H. Thomas  Gao  Dongying  Holbrook  C. Corley  Ozias-Akins  Peggy 《Genetic Resources and Crop Evolution》2021,68(7):2883-2896

Genetic Resources and Crop Evolution - Peanut improvement is limited by a narrow genetic base. However, this obstacle can be circumvented by incorporating phenotypic variability from wild, diploid...  相似文献   

Simulation and sensitivity study of potato flake food processing     

Michael F. Kozempel  Peggy Tomasula  James C. Craig 《American Journal of Potato Research》1993,70(2):93-100

We made a sensitivity study of the potato flake process using the ERRC Food Process Simulator computer program with cost as the primary objective function. The study showed that labor was the largest component of the processing cost followed by capital related expenses. Pilot plant operation demonstrated the feasibility of reducing labor requirements. Capital related expenses could be minimized by using four drum dryers to more closely match the through put of the rest of the process. In addition, the drum dryers should be run as close to 8% moisture as possible without exceeding 8% to optimize the yield of finished product. This study demonstrates the feasibility of using the ERRC Food Process Simulator to do a sensitivity study of potato processing.  相似文献   

Effect of Insecticide Application on Cassava Yield in Control of Cassava Mealybug (Phenacoccus Manlhotl)     

Peggy E. Ellis  E. D. Morgan  A. P. Woodbridge 《国际虫害防治杂志》2013,59(3):434-446

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Diversity in attitudes toward farming and patterns of work among farm women: A regional comparison     

Peggy F. Barlett  Linda Lobao  Katherine Meyer 《Agriculture and Human Values》1999,16(4):343-354

Attention to diversity in women's attitudes toward farming and in women's patterns of farm work activity expands our understanding of the linkage between agrarian structure, regional history, and the behavior and values of individual farm women. We combine several disciplinary and methodological approaches to reveal patterns in work and values in a Southern case and then verify the existence of similar patterns in the Midwest. Two divergent conceptions of women's relationship to farm and marital partnership were found in a Georgia study, the agrarian and the industrial, and we explore how they emerged in the context of the political and economic history of the South. We find these marital models are linked today to different patterns of farm work. We then extend the Georgia analysis to a statewide survey of Ohio farm women, where attitudinal diversity is not as marked, due to the stronger agrarian traditions of the Midwest and its distinct political economy. We find similar patterns, however, in Ohio farm women's work and affirm the validity of Carbert's categorization of Rosenfeld's survey items. Attention to diversity in the work patterns, values, and attitudes of farm women highlights that the term traditional is a misnomer when applied to Southern women and reinforces the value of multi-disciplinary approaches and regional comparisons.  相似文献   

The changing ethnic composition of farmworkers in Dade County,Florida     

Peggy L. Webster 《Agriculture and Human Values》1985,2(3):68-70

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Purification and Characterization of a New Class of Insect α-Amylase Inhibitors from Barley     

Ningyan Zhang  Berne L. Jones  H. Peggy Tao 《Cereal Chemistry》1997,74(2):119-122

Barley seeds contain proteins that apparently protect them against attack by microorganisms and insects. Studies of these barley defensive proteins may lead to the development of barleys with improved natural resistance to pests. We have purified two low molecular weight proteins, designated BIα1 and BIα2, from barley grain, using ion-exchange chromatography and reversed-phase and gel-permeation high-performance liquid chromatography (HPLC). Both BIα1 and BIα2 inhibited insect (yellow meal worm, Tenebrio molitor) α-amylase activities. For the T. molitor α-amylase, the IC50 values of BIα1 and BIα2 were 80 μg/mL (12.5 μM) and 34 μg/mL (6.8 μM), respectively. Neither protein inhibited either human salivary α-amylase, barley α-amylase, or trypsin activities. N-terminal amino acid sequences of the inhibitors were highly homologous with those of the plant proteins called defensins. The first 20 N-terminal amino acids of BIα2 were identical to those of γ-hordothionin, but neither BIα1 nor BIα2 protein showed any homology with the chloroform-methanol (CM) soluble protein amino acid consensus sequence. The two inhibitors therefore apparently comprise another group of low molecular weight barley proteins that inhibit the α-amylase activities of some insects that attack cereal grains.  相似文献