The effects of a compressible plastic shoe - The Seattle shoe®- on the kinematics of the strides of galloping thoroughbred horses     

Patrick D. Wilson MS  DVM  Marc H. Ratzlaff DVM  PhD  Barrie D. Grant DVM  MS  Martha L. Hyde PhD  Olin K. Balch DVM  MS 《Journal of Equine Veterinary Science》1992,12(6):374-381

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Coagulopathic Effects and Therapy of Brodifacoum Toxicosis in Dogs     

Benny J. Woody DVM  MS    Michael J. Murphy DVM  PhD    AIlen C. Ray PhD  Robert A. Green DVM  PhD 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1992,6(1):23-28

The clinical signs and laboratory changes of brodifacoum (BDF) intoxicated dogs and their response to vitamin K1 treatment were examined. Brodifacoum, a second-generation anticoagulant rodenticide, was fed to four dogs for 3 consecutive days producing a cumulative dose of 1.1 mg BDF/kg body weight. Clinical observations of the animals were made daily throughout the study. Monitored laboratory parameters included: one-stage prothrombin time (OSPT), activated partial thromboplastin time (APTT), activated coagulation time (ACT), complete blood counts, thrombocyte counts, and serum chemistry values. Response to vitamin K1 therapy was evaluated clinically and by laboratory tests. Serum BDF concentrations were monitored. Inappetence and hemorrhagic tendencies were exhibited by day 5 postrodenticide exposure. One-stage prothrombin time, APTT, and ACT were 25% greater than time zero values at 24, 24, and 72 hours postdosing, respectively. All laboratory parameters returned to normal within 48 hours of initiating vitamin K1 therapy (0.83 mg/kg orally, TID for 5 days). Serum brodifacoum concentrations were highest (1065-1215 ng/mL) during the 3 days after BDF dosing and were detectable (3.0-7.5 ng/mL) until day 24 postexposure. A mean BDF elimination half-life of 6 +/- 4 days was observed.  相似文献   

Dilated Cardiomyopathy in Juvenile Doberman Pinschers     

Andrea Vollmar DVM  Dipl. ECVIM-CA  Philip R. Fox DVM  MSc  Dipl. ACVIM  ECVIM-CA  Dipl. ACVECC  Kathryn M. Meurs DVM  PhD  Dipl. ACVIM  Si-Kwang Liu DVM  PhD  Dipl. ACVIM 《Journal of Veterinary Cardiology》2003,5(1):637

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Our changing world     

William E. Jones DVM  PhD  Editor 《Journal of Equine Veterinary Science》2003,23(12):514

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MAGNETIC RESONANCE IMAGING OF THE EQUINE STIFLE     

Susan J.  Holcombe  VMD  MS  Alicia L.  Bertone  DVM  PhD  David S.  Biller  DVM  Valerie  Haider  DVM 《Veterinary radiology & ultrasound》1995,36(2):119-125

The purpose of this study was to define normal gross anatomic structures in the equine stifle with magnetic resonance images. Magnetic resonance (MR) images were made in sagittal, 15° supinated, transverse, and dorsal planes of two equine stifles. The MR images were scrutinized by comparing MR images to dissection specimens and frozen cross sections of stifle joints. Sagittal and 15° supinated images were the most valuable in assessing articular cartilage, subchondral bone, and soft tissue structures within the joint. Cranial and caudal cruciate ligaments, medial and lateral menisci, meniscotibial and meniscofemoral ligaments, long digital extensor tendon, and patellar ligaments were easily evaluated. MR images provided substantially more gross anatomical information than the currently available imaging modalities.  相似文献   

A Comparison of the Cutaneous Trunci Myocutaneous Flap and Latissimus Dorsi Myocutaneous Flap in the Dog     

MICHAEL M. PAVLETIC DVM  DiplomateACVs    MARILYN KOSTOLICH DVM    PHILIP KOBLIK DVM  PhD  STEVE ENGLER VMD 《Veterinary surgery : VS》1987,16(4):283-293

Latissimus dorsi and cutaneous trunci myocutaneous flaps of equal dimension and location were randomly elevated on opposite sides of the thorax in 10 dogs (group 1) and resutured to their respective bed. The procedure was repeated in four additional dogs (group 2); however, the short perforating branches of the thoracodorsal artery and vein were divided at the base of each cutaneous trunci myocutaneous flap, whereas the cutaneous pedicle and underlying cutaneous trunci muscle were divided in the latissimus dorsi myocutaneous flaps to determine subsequent skin survivability and the major source of circulation of each myocutaneous flap. There was little difference in the percentage of skin survival between the latissimus dorsi and cutaneous trunci myocutaneous flaps in group 1 dogs. Circulation to the "skin island" of group 2 latissimus dorsi myocutaneous flaps originated from intramuscular anastomotic connections between the major branch of the thoracodorsal artery entering the latissimus dorsi muscle and the proximal lateral intercostal arteries perforating the muscle. Ligation of the short perforating branches of the thoracodorsal artery resulted in partial skin necrosis in all group 2 cutaneous trunci myocutaneous flaps. Results from this study indicate that it is unnecessary to elevate the latissimus dorsi muscle for major skin flap elevation and survival. The thicker latissimus dorsi myocutaneous flap is more difficult to develop surgically and appears to have no clinical major advantage over the more mobile cutaneous trunci myocutaneous flap or the adjacent thoracodorsal axial pattern flap for closure of large skin defects within the radius of flap rotation.  相似文献   

NSAIDs     

Dr Anthony Blikslager DVM  PhD  DACVS  Associate Professor  Dr Sam Jones DVM  PhD  DACVIM  Associate Professor 《Journal of Equine Veterinary Science》2005,25(3):98-102

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Behavioral and physiological responses to stabling in naive horses     

E. J. Harewood BAppSc  C. M. McGowan BVSc  DipVetClinStud  PhD 《Journal of Equine Veterinary Science》2005,25(4):164-170

The purpose of this study was to investigate the response of horses to confinement and isolation in a stable (indoor individual housing) for the first time using behavioral indices, heart rate, and salivary cortisol concentration. Six naive 2-year-old Australian Stock Horse fillies were examined at 4-hour intervals over 24 hours in an outdoor group paddock followed by 24 hours in indoor individual housing. Behavioral observations and scores and heart rates were recorded and saliva samples were taken at each interval. During stabling, all horses became agitated and demonstrated increased vocalization and movement. Behavioral scores were significantly higher in the indoor individual housing (P < .001). No significant difference in heart rates between the two environments was detected. Mean salivary cortisol did not increase significantly (2 ng/mL ± 1.4 ng/mL in outdoor group paddock vs 2.5 mL ± 1.2 ng/mL in indoor individual housing). No diurnal rhythm in salivary cortisol was evident in either the outdoor group paddock or indoor individual housing. The results of this study highlight that a combination of behavioral and physiological measures allow better understanding of stress, where one measurement may be misleading. First time stabling of horses elicited marked behavioral responses indicative of stress that were not reflected in increased heart rates or salivary cortisol concentrations. The lack of a diurnal cortisol rhythm and the comparatively high basal cortisol concentrations found in the outdoor group paddock environment may imply that the fillies were already stressed; therefore, stabling did not cause further aberrations detectable by salivary cortisol analysis.  相似文献   

Scientific training     

William E. Jones DVM  PhD 《Journal of Equine Veterinary Science》2005,25(7):95-321

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Effects of intravenous sodium bicarbonate and sodium acetate on equine acid-base status     

Kevin Kline PhD  Leonard P. Frey PhD  Jonathan H. Foreman DVM  MS  Joseph T. Lyman DVM  MS 《Journal of Equine Veterinary Science》2005,25(8):349-354

Changes in blood gases, pH, and plasma electrolyte concentrations in response to intravenously infused sodium bicarbonate (NaHCO₃) and sodium acetate (NaCH₃CO₂) solutions (1.34 mEq/mL) in 5 light breed mares were investigated. Jugular venous blood samples were collected before and after completion of the infusions in 20-minute intervals for 200 minutes. Infusion of sodium bicarbonate and sodium acetate caused significant (P < .00l) increases in blood pH and bicarbonate ion concentration that persisted throughout the collection period. The elevation in blood pH and bicarbonate ion concentrations was greater (P < .01) for sodium bicarbonate than for sodium acetate immediately after the completion of the infusions but was not different (P > .05) thereafter. There were significant reductions (P < .01) in plasma-ionized calcium and potassium after infusion of both sodium bicarbonate and sodium acetate. This study found that significant metabolic alkalosis in horses and corresponding shifts in electrolyte concentrations can be induced by intravenous infusion of solutions of either sodium bicarbonate or sodium acetate, and they persist for at least 3 hours. These data show that the short-term elevation in pH and bicarbonate ion concentration is momentarily higher after infusion of sodium bicarbonate. This is likely due to the direct infusion of bicarbonate ions in the sodium bicarbonate treatment, such that further metabolism is not required to be effective. However, the longer-term alkalosis did not differ between isomolar solutions of sodium bicarbonate and sodium acetate.  相似文献