Global transcription analysis of vaccinated channel catfish following challenge with virulent Edwardsiella ictaluri     

Pridgeon JW  Yeh HY  Shoemaker CA  Klesius PH 《Veterinary immunology and immunopathology》2012,146(1):53-61

  相似文献   

The biosynthetic products of Chinese insect medicine, Aspongopus chinensis     

Luo XH  Wang XZ  Jiang HL  Yang JL  Crews P  Valeriote FA  Wu QX 《Fitoterapia》2012,83(4):754-758

A new oxazole (1) was obtained from Chinese insect medicine Aspongopus chinensis, along with three known N-acetyldopamine derivatives (2-4). Their structures were determined on the basis of NMR and ESI-MS analyses. The possible biosynthetic pathways of the isolated compounds are discussed. Cytotoxicities of those compounds against 10 selected cancer cells were measured in vitro.  相似文献   

Risk factors for feline infectious peritonitis in Australian cats     

Worthing KA  Wigney DI  Dhand NK  Fawcett A  McDonagh P  Malik R  Norris JM 《Journal of Feline Medicine and Surgery》2012,14(6):405-412

The objective of this study was to determine whether patient signalment (age, breed, sex and neuter status) is associated with naturally-occurring feline infectious peritonitis (FIP) in cats in Australia. A retrospective comparison of the signalment between cats with confirmed FIP and the general cat population was designed. The patient signalment of 382 FIP confirmed cases were compared with the Companion Animal Register of NSW and the general cat population of Sydney. Younger cats were significantly over-represented among FIP cases. Domestic crossbred, Persian and Himalayan cats were significantly under-represented in the FIP cohort, while several breeds were over-represented, including British Shorthair, Devon Rex and Abyssinian. A significantly higher proportion of male cats had FIP compared with female cats. This study provides further evidence that FIP is a disease primarily of young cats and that significant breed and sex predilections exist in Australia. This opens further avenues to investigate the role of genetic factors in FIP.  相似文献   

Extraocular lymphoma in the horse     

Allison T. Schnoke  Dennis E. Brooks  David A. Wilkie  Ann E. Dwyer  Andrew G. Matthews  Brian C. Gilger  Diane V. H. Hendrix  Phillip Pickett  Magda Grauwels  Christine Monroe  Caryn E. Plummer 《Veterinary ophthalmology》2013,16(1):35-42

  相似文献   

Latent and active polyphenol oxidase (PPO) in red clover (Trifolium pratense) and use of a low PPO mutant to study the role of PPO in proteolysis reduction     

Winters AL  Minchin FR  Michaelson-Yeates TP  Lee MR  Morris P 《Journal of agricultural and food chemistry》2008,56(8):2817-2824

Polyphenol oxidase (PPO) activity in leaf extracts of wild type (WT) red clover and a mutant line expressing greatly reduced levels of PPO (LP red clover) has been characterized. Both latent and active forms of PPO were present, with the latent being the predominant form. PPO enzyme and substrate (phaselic acid) levels fluctuated over a growing season and were not correlated. Protease activation of latent PPO was demonstrated; however, the rate was too low to have an immediate effect following extraction. A novel, more rapid PPO activation mechanism by the enzyme's own substrate was identified. Rates of protein breakdown and amino acid release were significantly higher in LP red clover extracts compared with WT extracts, with 20 versus 6% breakdown of total protein and 1.9 versus 0.4 mg/g FW of free amino acids released over 24 h, respectively. Inclusion of ascorbic acid increased the extent of protein breakdown. Free phenol content decreased during a 24 h incubation of WT red clover extracts, whereas protein-bound phenol increased and high molecular weight protein species were formed. Inhibition of proteolysis occurred during wilting and ensilage of WT compared with LP forage (1.9 vs 5 and 17 vs 21 g/kg of DM free amino acids for 24 h wilted forage and 90 day silage, respectively). This study shows that whereas constitutive red clover PPO occurs predominantly in the latent form, this fraction can contribute to reducing protein breakdown in crude extracts and during ensilage.  相似文献   

Propofol versus thiopental: effects on peri-induction intraocular pressures in normal dogs     

Hofmeister EH  Williams CO  Braun C  Moore PA 《Veterinary anaesthesia and analgesia》2008,35(4):275-281

ObjectiveTo determine the effects of propofol or thiopental induction on intraocular pressures (IOP) in normal dogs.Study designProspective randomized experimental study.AnimalsTwenty-two random-source dogs weighing 19.5 ± 5.3 kg.MethodsDogs were randomly assigned to receive propofol 8 mg kg⁻¹ IV (group P) or thiopental 18 mg kg⁻¹ IV (group T) until loss of jaw tone. Direct arterial blood pressure, arterial blood gasses, and IOP were measured at baseline, after pre-oxygenation but before induction, before endotracheal intubation, and after intubation.ResultsThere were no significant differences between groups with regard to weight, body condition score, breed group, or baseline or before-induction IOP, arterial blood pressure, or blood gases. The baseline IOP was 12.9 mmHg. Before endotracheal intubation, IOP was significantly higher compared to baseline and before induction in dogs receiving propofol. After intubation with propofol, IOP was significantly higher compared to thiopental and was significantly higher compared to before induction. After intubation, IOP was significantly lower compared to before intubation in dogs receiving thiopental. Propofol increased IOP before intubation by 26% over the before-induction score and thiopental increased IOP by 6% at the same interval. The IOP in group P remained 24% over the before induction score whereas thiopental ultimately decreased IOP 9% below baseline after intubation. There was no significant relationship between any cardiovascular or blood gas parameter and IOP at any time. There was no significant relationship between the changes in any cardiovascular or blood gas parameter and the changes in IOP between time points.Conclusions and clinical relevancePropofol caused a significant increase in IOP compared to baseline and thiopental. Thiopental caused an insignificant increase in IOP which decreased after intubation. Propofol should be avoided when possible in induction of anesthesia in animals where a moderate increase in IOP could be harmful.  相似文献   

Partial analytical validation of the VetScan cPL rapid test     

Joerg M. Steiner  Phillip Guadiano  Robynne R. Gomez  Jan S. Suchodolski  Jonathan A. Lidbury 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2019,48(4):683-690

  相似文献   

Correction to: Seroprevalence of bovine brucellosis and associated risk factors in Nakasongola district,Uganda     

Bugeza  James  Muwonge  Adrian  Munyeme  Musso  Lasuba  Phillip  Godfroid  Jacques  Kankya  Clovice 《Tropical animal health and production》2019,51(7):2077-2077

Tropical Animal Health and Production - In the originally published article, the name of the fifth author was incorrectly presented as Godfroid Jacques. The correct name is Jacques Godfroid.  相似文献   

Effect of oral trazodone on the minimum alveolar concentration of isoflurane in dogs     

Elizabeth A. Hoffman  Turi K. Aarnes  Carolina H. Ricco Pereira  Phillip Lerche  Richard M. Bednarski  Mary A. McLoughlin 《Veterinary anaesthesia and analgesia》2018,45(6):754-759

Objective

To determine the effect of oral trazodone on the minimum alveolar concentration (MAC) of isoflurane in dogs.

Study design

Prospective blinded, single-observer, randomized crossover experimental study.

Animals

Six adult (age 6.8 ± 1.6 months) healthy dogs (three males and three females), weighing 24.8 ± 3.4 kg (mean ± standard deviation).

Methods

Each dog was anesthetized twice with a minimum of 7 days between anesthetic episodes. Dogs were randomly assigned to be administered two treatments in a crossover design: premedication with trazodone (8 mg kg^?1; TRAZ–ISO) orally 2 hours prior to an anesthetic episode or no (ISO). Dogs were anesthetized with intravenous propofol (6 mg kg^?1) and isoflurane in >95% oxygen. Isoflurane MAC was determined using an iterative bracketing technique with electrodes placed in the buccal mucosa. Hemodynamic variables were compared at the lowest end-tidal isoflurane concentration at which each dog did not respond. A paired t test was used to assess the effect of treatment on outcome variables with significance set to a value of p < 0.05.

Results

The MAC concentration (mean ± standard deviation) in dogs administered TRAZ–ISO was 0.85 ± 0.17% compared with 1.02 ± 0.11% in those administered ISO (p = 0.01, 95% confidence interval ?0.25 to ?0.05), resulting in a mean MAC reduction of 17 ± 12%. There were no differences in hemodynamic variables between treatments.

Conclusions and clinical relevance

Premedication of dogs with oral trazodone (8 mg kg^?1) 2 hours prior to anesthetic induction has a significant isoflurane MAC sparing effect with no significant observed hemodynamic benefit.  相似文献   

A preliminary investigation of Ehrlichia species in ticks, humans, dogs, and capybaras from Brazil     

Labruna MB  McBride JW  Camargo LM  Aguiar DM  Yabsley MJ  Davidson WR  Stromdahl EY  Williamson PC  Stich RW  Long SW  Camargo EP  Walker DH 《Veterinary parasitology》2007,143(2):189-195

A molecular epidemiologic investigation in two Brazilian states (Rondônia and São Paulo) was undertaken to determine if Ehrlichia species responsible for human and animal ehrlichioses in North America could be found in Brazilian vectors, potential natural mammalian reservoirs and febrile human patients with a tick bite history. Samples, including 376 ticks comprising 9 Amblyomma species, 29 capybara (Hydrochaeris hydrochaeris) spleens, 5 canine blood, and 75 human blood samples from febrile patients with history of tick bites were tested by a real-time PCR assay targeting a fragment of the Ehrlichia dsb gene. Ehrlichia DNA was not detected in any tick, capybara or human samples. In contrast, 4 out of 5 dogs contained Ehrlichia canis DNA in their blood, which were sequenced, representing the first report of E. canis infecting dogs in the Amazon region of Brazil. Further studies are needed to evaluate the presence of other agents of human and animal ehrlichioses in Brazil.  相似文献