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21.
Risk factors associated with porcine cysticercosis in selected districts of Eastern and Southern provinces of Zambia 总被引:1,自引:0,他引:1
Sikasunge CS Phiri IK Phiri AM Dorny P Siziya S Willingham AL 《Veterinary parasitology》2007,143(1):59-66
To determine the risk factors associated with Taenia solium transmission in humans and pigs in the rural areas of Eastern and Southern provinces of Zambia, a questionnaire was administered in 788 households from 155 villages. Pigs were examined from 800 households. Tongue examination and enzyme-linked immunosorbent assay (Ag-ELISA) for the detection of circulating antigens of T. solium cysticerci were used to measure infection in pigs. A snowballing technique was utilised to select households with pigs. Prevalence of households with pigs infected with T. solium on tongue examination by district ranged from 12.7% to 32.1% with Ag-ELISA having a range of 30.0-51.7%. Of the total number of households visited, 18.8% and 37.6% had at least one pig positive for porcine cysticercosis on tongue examination and Ag-ELISA, respectively. Risk factors associated with T. solium infection were lack of pork inspection at slaughter (96.7%), consumption of pork with cysts (20.1%), selling of pork infected with T. solium cysticerci (18.3%), free-range husbandry system (83.2%) and absence of latrines (58.0). Free-range husbandry system (OR=1.68; 95% CI=1.36-2.07) was a significant risk factor for porcine cysticercosis in the surveyed areas. The result that pigs were mostly kept on free-range and semi-intensive husbandry systems may have permitted them to have access to eating human faeces that could be contaminated with tapeworm eggs. This study has shown that T. solium infection poses a high public health risk in the study areas and urban areas as well. We recommend that a human survey be conducted to verify the human exposure to taeniasis and/or cysticercosis in Zambia. 相似文献
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CEDAR M. CHITTENDEN BJØRN ÅDLANDSVIK OLE‐PETTER PEDERSEN DAVID RIGHTON AUDUN H. RIKARDSEN 《Fisheries Oceanography》2013,22(1):1-13
The use of pop‐up archival satellite tags (PSATs) to geolocate marine fishes in polar regions is challenging due to the brevity of periods during which there is a defined sunrise and sunset. Models using other environmental parameters are thus required to supplement geolocation data in the estimation of marine migratory routes. The objective of this work was to create a simple method that would estimate the migratory pathways of Atlantic salmon (Salmo salar) in polar regions using temperature and depth recordings. Validated geolocations from PSATs were used to test and constrict the model. The model’s predicted migratory routes were within 100 km of the light‐based geolocations calculated by the tags. By constraining the trajectories through the geolocations, bias was reduced. Sensitivity analyses demonstrated that slight alterations of the location and timing of the start and end points did not affect the mean migratory route estimates. This method is a management tool that can determine the primary habitat areas for any surface‐ or bottom‐dwelling marine species – especially in polar regions, where other methods may be impossible. 相似文献
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E. TYDÉN H. BJŐRNSTRŐM H. TJÄLVE P. LARSSON 《Journal of veterinary pharmacology and therapeutics》2010,33(4):332-340
Tydén, E., Bj?rnstr?m, H., Tjälve, H., Larsson, P. Expression and localization of BCRP, MRP1 and MRP2 in intestines, liver and kidney in horse. J. vet. Pharmacol. Therap. doi: 10.1111/j.1365‐2885.2009.01140.x. The gene and protein expression and the cellular localization of the ABC transport proteins breast cancer resistance protein (BCRP), multidrug resistance‐associated protein 1 (MRP1) and multidrug resistance‐associated protein 2 (MRP2) have been examined in the intestines, liver and kidney in horse. High gene and protein expression of BCRP and MRP2 were found in the small intestines, with cellular localization in the apical membranes of the enterocytes. In the liver, MRP2 was present in the bile canalicular membranes of the hepatocytes, whereas BCRP was localized in the cytoplasm of hepatocytes in the peripheral parts of the liver lobuli. In the kidney both BCRP and MRP2 were predominantly present in the distal tubuli and in the loops of Henle. In most tissues, the gene and protein expression of MRP1 were much lower than for BCRP and MRP2. Immunostaining of MRP1 was detectable only in the intestines and with localization in the cytoplasm of enterocytes in the caecum and colon and in the cells of serous acini of Brunner’s glands in the duodenum and the upper jejunum. The latter cells were also stained for BCRP, but not for MRP2. Many drugs used in horse are substrates for one or more of the ABC transport proteins. These transporters may therefore have important functions for oral bioavailability, distribution and excretion of substrate compounds in horse. 相似文献
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Testosterone and androstenedione were measured in the plasma of mature tom-cats before, during and after anesthesia with thiopentone, ketamine, xylazine and alphaxolone/alphadolone. Samples were collected via an indwelling jugular catheter at 30 min intervals before anesthesia (5 samples) and during the recovery phase (8 samples), and at intervals of 15 min during anesthesia (7 samples). Thiopentone and ketamine anesthesia significantly depressed testosterone and androstenedione concentrations during and after anesthesia. Xylazine significantly increased testosterone concentrations during anesthesia but they returned to pre-anesthetic concentrations during recovery. Androstenedione concentrations were significantly depressed during the recovery phase from xylazine anesthesia. Alphaxolone/alphadolone anesthesia had no significant effect of testosterone concentrations but significantly increased and androstenedione concentrations during anesthesia and recovery. Testosterone and androstenedione concentrations in cats were significantly altered by these 4 commonly used anesthetics and this must be taken into account if hormone concentrations are measured while cats are anesthetised. 相似文献
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Ataxia and paralysis in cats in Australia associated with exposure to an imported gamma-irradiated commercial dry pet food 总被引:1,自引:1,他引:0
Between June 2008 and March 2009, 87 cats in Australia developed symmetrical hindlimb ataxia, paraparesis, tetraparesis, paraplegia or tetraplegia in association with eating an imported, irradiated dry pet food. This communication reports the clinical signs and outcomes of those cats. 相似文献
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Munyeme M Muma JB Samui KL Skjerve E Nambota AM Phiri IG Rigouts L Tryland M 《Tropical animal health and production》2009,41(3):345-352
A cross-sectional study was conducted to investigate the prevalence and animal level risk factors for bovine tuberculosis (BTB) in indigenous cattle of the livestock/wildlife interface areas in Zambia. A total of 944 cattle from 111 herds were investigated. The comparative intradermal tuberculin test (CIDT) was used to identify reactor animals for BTB. Animal level data on sex, age, parity and body condition score were registered. The overall animal prevalence of BTB as determined by the CIDT was 6.8% (95% CI: 4.2, 9.5%). In Lochinvar and Blue Lagoon areas, animal level prevalence were observed at 5.2% (95% CI: 2.2, 8.2%) and 9.6% (95% CI: 6.1, 13.2%), respectively. Kazungula, an area outside the livestock/wildlife interface, had a prevalence of only 0.8% (95% CI: 0.0, 2.3%). The age of the animal, its body condition score and the type of management system, were predictive of its BTB status. The study revealed that BTB was relatively high in the livestock/wildlife interface areas of Lochinvar and Blue Lagoon compared to Kazungula. These findings should raise a serious public health concern considering the extent to which the communities of the study areas are in contact with their animals and the levels at which they use untreated milk. 相似文献
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Gabriël S Dorny P Duchateau L Phiri IK Chembensofu M Vercruysse J 《Veterinary parasitology》2005,130(1-2):55-60
Thirty red-legged partridges (Alectoris rufa), 5-month-old, were orally inoculated with oocysts of the OV-51/95 strain of Toxoplasma gondii. Birds were distributed into five groups and received, respectively, 10 (group A, 4 birds), 50 (group B, 14 birds), 10(2) (group C, 4 birds), 10(3) (group D, 4 birds) and 10(4) (group E, 4 birds) oocysts. One partridge from group B and one from group E died suddenly of acute toxoplasmosis at 7 day after inoculation (DAI) with demonstrable T. gondii in several tissues. The rest of birds remained clinically normal until killed at 44, 58, 65, 72, 79 or 100 DAI. Brain, heart, liver and skeletal muscle from these partridges were bioassayed individually in mice; T. gondii was demonstrated in all these tissues, except in heart of three birds inoculated, respectively, with 10, 50 and 10(2) oocysts. Lesions were not seen in histologic sections of tissues from surviving partridges. These results suggest that red-legged partridges are resistant to clinical toxoplasmosis. 相似文献