Serological evidence for the presence of Leptospira interrogans serovar bratislava in Australian pigs     

RJ RICHAPPEL  WA ELLIS†  B ADLER‡  L AMON  BD MILLAR§  SS ZHU  RW PRIM§ 《Australian veterinary journal》1992,69(5):119-120

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Effects of racing and nontraining on plasma thyroid hormone concentrations in sled dogs     

Lee JA  Hinchcliff KW  Piercy RJ  Schmidt KE  Nelson S 《Journal of the American Veterinary Medical Association》2004,224(2):226-231

OBJECTIVE: To determine the effects of racing and nontraining on plasma thyroxine (T4), free thyroxine (fT4), thyroid-stimulating hormone (TSH), and thyroglobulin autoantibody (TgAA) concentrations in sled dogs and compare results with reference ranges established for dogs of other breeds. DESIGN: Cross-sectional study. ANIMALS: 122 sled dogs. PROCEDURE: Plasma thyroid hormone concentrations were measured before dogs began and after they finished or were removed from the Iditarod Trail Sled Dog Race in Alaska and approximately 3 months after the race. RESULTS: Concentrations of T4 and fT4 before the race were less than the reference range for nonsled dogs in 26% and 18% of sled dogs, respectively. Immediately after racing, 92% of sled dogs had plasma T4 concentrations less than the reference range. Three months after the race, 25% of sled dogs had plasma T4 concentrations less than the reference range. For T4, fT4, TSH, and TgAA, significant differences were not detected in samples collected before the race versus 3 months later. CONCLUSIONS AND CLINICAL RELEVANCE: Plasma T4, fT4, and TSH concentrations decreased in dogs that complete a long distance sled dog race. Many clinically normal sled dogs have plasma T4 and fT4 values that are lower than the reference range for nonsled dogs. We suggest that the reference ranges for sled dogs are 5.3 to 40.3 nmol/L and 3.0 to 24.0 pmol/L for plasmaT4 and fT4 concentrations, respectively, and 8.0 to 370 mU/L for TSH.  相似文献   

Expression of TOLL-like receptors (TLR) by bovine antigen-presenting cells-potential role in pathogen discrimination?     

Werling D  Piercy J  Coffey TJ 《Veterinary immunology and immunopathology》2006,112(1-2):2-11

Invading pathogens are controlled by the innate and adaptive arms of the immune system. Adaptive immunity, mediated by B and T lymphocytes, recognises pathogens via high affinity receptors. However, the establishment of a primary adaptive immune response is not rapid enough to eradicate invading microorganisms as it involves cell proliferation, gene activation and protein synthesis. More rapid defence mechanisms are provided by innate immunity, which recognises invading pathogens by germ-line-encoded pattern recognition receptors. Recent evidence shows that this recognition can mainly be attributed to the family of TOLL-like receptors (TLR). Binding of pathogen-associated molecular patterns to TLR induces the production of reactive oxygen and nitrogen intermediates, pro-inflammatory cytokines, and up-regulates expression of co-stimulatory molecules, subsequently initiating the adaptive immunity. In this paper, we will discuss the current knowledge with regards to the TLR, and in particular the bovine family of TLR. In addition, we will show the expression of TLR mRNA in bovine antigen-presenting cell subsets, summarise the discovery and the critical roles of TLR2 in host defence against Mycobacteria, and provide evidence for a mycobacteria species-specific response of bovine macrophages.  相似文献   

Measurements of the equation of state of deuterium at the fluid insulator-metal transition   总被引：1，自引：0，他引：1  

GW Collins  Da Silva LB  P Celliers  DM Gold  ME Foord  RJ Wallace  A Ng  SV Weber  KS Budil  R Cauble 《Science (New York, N.Y.)》1998,281(5380):1178-1181

A high-intensity laser was used to shock-compress liquid deuterium to pressures from 22 to 340 gigapascals. In this regime deuterium is predicted to transform from an insulating molecular fluid to an atomic metallic fluid. Shock densities and pressures, determined by radiography, revealed an increase in compressibility near 100 gigapascals indicative of such a transition. Velocity interferometry measurements, obtained by reflecting a laser probe directly off the shock front in flight, demonstrated that deuterium shocked above 55 gigapascals has an electrical conductivity characteristic of a liquid metal and independently confirmed the radiography.  相似文献   

Serological survey for Brucella antibodies in feral pigs from eastern Australia     

RJ MASON  PJS FLEMING 《Australian veterinary journal》1999,77(5):331-332

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Vertebral embryology and equine congenital vertebral anomalies     

V. E. Unt  R. J. Piercy 《Equine Veterinary Education》2009,21(4):212-214

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Clinical application of multidetector computed tomography and magnetic resonance imaging for evaluation of cranial nerves in horses in comparison with high resolution imaging standards          下载免费PDF全文

J. Dixon  R. Lam  R. Weller  G. Manso‐Díaz  M. Smith  R. J. Piercy 《Equine Veterinary Education》2017,29(7):376-384

Although horses are affected by cranial nerve disease, our understanding of these structures' imaging anatomy is limited, and the optimal modality for imaging of each of these nerves is unclear. The aim of this study was to describe the imaging appearance of the equine cranial nerves on high‐resolution 1.5T magnetic resonance imaging (MRI) and computed tomography (CT) scans of a cadaver head, and with these as standards, examine the utility of MRI and CT performed in clinical cases. High‐resolution MRI and CT images were prospectively acquired of the head of a normal Thoroughbred gelding following euthanasia. Ten clinical cases undergoing high‐field MRI under general anaesthesia and 10 clinical cases undergoing CT in the standing horse under sedation were retrospectively evaluated by three reviewers to assess cranial nerve visibility. On high‐resolution, thin‐slice, MRI scans of the normal cadaver head, each of the 12 cranial nerves and their topographic location could be appreciated. On high‐resolution cadaver CT, cranial nerves II, V and VII were clearly visible, but others were less easily identified; osseous structures were clearly visualised. Clinical MRI and CT allowed for variable visualisation of the cranial nerves, dependent on the sequence and the orientation of scan planes. High‐field MRI allowed excellent visualisation of equine cranial nerves, whereas CT allowed for more detailed visualisation of the osseous canals and foramina. In live horses, the ability to identify all 12 nerves is challenging with either MRI or CT; however, high‐field MRI enables better visualisation of the nerve bundles than CT.  相似文献   

Equine atypical myopathy in the UK: Epidemiological characteristics of cases reported from 2011 to 2015 and factors associated with survival          下载免费PDF全文

S. González‐Medina  J. L. Ireland  R. J. Piercy  J. R. Newton  D. M. Votion 《Equine veterinary journal》2017,49(6):746-752

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Prevalence of Cysticercus bovis in Australian cattle     

BHG Pearse  RJ Traub  A Davis  R Cobbold  PB Vanderlinde 《Australian veterinary journal》2010,88(7):260-262

Objective The first national abattoir survey of Cysticercus bovis (‘beef measles’) in cattle was conducted in February 2008. Methods During the data collection period, 493,316 cattle were subjected to standard postmortem procedures, including incision of the masseter and heart muscles. On-site veterinarians were asked to record the location of any C. bovis cysts, as well as the National Livestock Identification System ear tag numbers of infected animals. Veterinarians were asked to submit samples for laboratory confirmation by histology and polymerase chain reaction testing. Results Of the 23 samples submitted, none was positive for C. bovis by either diagnostic method. Conclusions Occasional, isolated diagnoses of beef measles are still made in most states of Australia, but since the last regional surveys were conducted 30 years ago, when the estimated prevalence was 50 to 200 per 100,000 cattle slaughtered, the parasite has become extremely rare.  相似文献   

Hydranencephaly in a foal     

K. Baiker  N. Saunders  B. A. Summers  R. J. Piercy  K. Smith 《Equine Veterinary Education》2010,22(12):593-598

Hydranencephaly is well recognised in several domestic animals, especially ruminants, but is virtually unknown in the horse. This case report describes a premature filly foal that on the day of delivery was found with a severe neurological disorder that initially improved but then progressively worsened. The foal was subjected to euthanasia on humane grounds and post mortem examination revealed somewhat asymmetric but bilateral destruction of the telencephalon identified as hydranencephaly. The possible causes of hydranencephaly in foals are discussed.  相似文献