THE INCIDENCE OF INTERDIGITAL SKIN DISEASES IN FLOCKS OF SHEEP FREE OF VIRULENT FOOT-ROT     

I. R. Morgan  D. W. Piercy  † J. R. Egerton  † 《Australian veterinary journal》1972,48(1):23-25

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Assessment of the potential toxicity of a poison for rabbits, pindone (2-pivalyl 1, 3 indandione), to domestic animals     

GR MARTIN  RJ SUTHERLAND†  ID ROBERTSON†  WE KIRKPATRICK  DR KING  PJ HOOD† 《Australian veterinary journal》1991,68(7):241-243

The toxicity of pindone, a rabbit poison, to horses, cattle, goats, chickens, dogs and cats was investigated, using extension of prothrombin time (PT) as an index of poisoning. The daily dose of pindone, administered for 5 days, ranged from 0.3 mg/kg for dogs to 2.5 mg/kg for chickens. This range of dose rates was considered to be indicative of the worst possible case that could arise following a campaign of baiting for rabbits. Although significant elevations in PT (more than double baseline values) were noted in all species other than horses, clinical signs of anticoagulant poisoning were not observed in any of the species tested. From the observed PT, cattle and cats appeared to be the most susceptible, and horses the least susceptible, to pindone toxicity. The half-lives of the elevated PT were calculated as 3.1 days for cattle, 2.8 days for goats and chickens, 1.9 days for horses and dogs and less than one day for cats. It is proposed that these half-lives can be used as a guide for determining the duration of treatment of pindone-affected animals.  相似文献   

Anaphylaxis in young calves inoculated with heat-inactivated Mycoplasma mycoides     

D W Piercy 《Research in veterinary science》1970,11(5):481-483

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Isolation of Mycobacterium avium subsp paratuberculosis from the semen of rams with clinical Johne''s disease     

J EPPLESTON  RJ WHITTINGTON 《Australian veterinary journal》2001,79(11):776-777

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Detection of Clostridium botulinum types C and D toxin by ELISA   总被引：3，自引：0，他引：3  

RJ THOMAS 《Australian veterinary journal》1991,68(3):111-113

An ELISA to detect Clostridium botulinum type D toxin was developed using polyclonal antibodies to a semi-purified toxic complex of the neurotoxin. Sensitivity of the ELISA for detecting type C and type D toxin compared with mouse inoculation was 70% and specificity 96% on samples from animals with botulism diagnosed on clinical signs and herd history. However, both mouse inoculation and the ELISA failed to detect toxin in many animals with a presumptive diagnosis of botulism. Some cross-reaction was seen with Clostridium novyi type A, but not with other clostridial species. While the ELISA described here cannot replace mouse inoculation for the diagnosis of botulism, it is a useful additional test.  相似文献   

Chronic cannulation of the mandibular salivary duct in sheep     

D W Piercy 《Research in veterinary science》1972,13(4):383-385

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Effect of dietary supplements containing antioxidants on attenuation of muscle damage in exercising sled dogs     

Piercy RJ  Hinchcliff KW  DiSilvestro RA  Reinhart GA  Baskin CR  Hayek MG  Burr JR  Swenson RA 《American journal of veterinary research》2000,61(11):1438-1445

OBJECTIVE: To determine whether dietary antioxidants would attenuate exercise-induced increases in plasma creatine kinase (CK) activity in sled dogs. ANIMALS: 41 trained adult sled dogs. PROCEDURE: Dogs, randomly assigned to 2 groups, received the same base diet throughout the study. After 8 weeks on that diet, 1 group (21 dogs) received a daily supplement containing vitamins E (457 U) and C (706 mg) and beta-carotene (5.1 mg), and a control group (20 dogs) received a supplement containing minimal amounts of antioxidants. After 3 weeks, both groups performed identical endurance exercise on each of 3 days. Blood samples were collected before and 3 weeks after addition of supplements and after each day of exercise. Plasma was analyzed for vitamins E and C, retinol, uric acid, triglyceride, and cholesterol concentrations, total antioxidant status (TAS), and CK activity. RESULTS: Feeding supplements containing antioxidants caused a significant increase in vitamin E concentration but did not change retinol or vitamin C concentrations orTAS. Exercise caused significantly higher CK activity, but did not cause a significant difference in CK activity between groups. Exercise was associated with significantly lower vitamin E, retinol, and cholesterol concentrations and TAS but significantly higher vitamin C, triglyceride, and uric acid concentrations in both groups. CONCLUSIONS AND CLINICAL RELEVANCE: Use of supplements containing the doses of antioxidants used here failed to attenuate exercise-induced increases in CK activity. Muscle damage in sled dogs, as measured by plasma CK activity, may be caused by a mechanism other than oxidant stress.  相似文献   

Unusual pathophysiological mechanisms of ptyalism in two horses     

R. B. Olley  R. J. Piercy  G. Leeming  C. M. McGowan 《Equine Veterinary Education》2021,33(2):e45-e50

This report outlines two cases of ptyalism that were not associated with oral conditions or primary dysphagia. The first, a 9-year-old Thoroughbred gelding, was associated with left-sided peripheral vestibular disease and bone modelling around the left tympanic bulla. The second, a 7-year-old Dutch Warmblood mare, was associated with progressive bilateral laryngeal paralysis and a mediastinal T-cell lymphoma. In Case 1, a neurological pathophysiology was proposed involving altered autonomic innervation of the salivary glands; whilst in Case 2, the mechanism remains unclear but may have involved mechanical compression of the intrathoracic oesophagus or stimulation of afferents within the vagus nerve. This case series highlights rare causes of ptyalism that have not been previously reported in the literature.  相似文献   

Detection of hypoglycin A and MCPA-carnitine in equine serum and muscle tissue: Optimisation and validation of a LC-MS–based method without derivatisation     

Sonia González-Medina  Carolyne Hyde  Imogen Lovera  Richard J. Piercy 《Equine veterinary journal》2021,53(3):558-568

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Proposed design modifications to reduce risk of operating rotary field mowers     

White KL  Wells LG  Shearer SA  Piercy LR 《Journal of agricultural safety and health》2000,6(4):249-259

The primary objective of this project was to reduce risk of injury associated with operating a rotary mower driven by a tractor power take-off (PTO) by developing and evaluating design improvements and determining their economic feasibility. Researchers have concluded that alteration of machinery design has a greater impact on the reduction of accidents than safety training. Implementation of an Operator Presence Sensing System (OPSS) and removal of the PTO are the two injury-reducing, engineering modifications evaluated by this research. Hydraulic power allows this to occur by providing dynamic braking, few moving parts (removal of the PTO), and controllable power. A hydraulic circuit was developed to power the mower and to enable an OPSS. Tractor hydraulics were simulated using a hydraulic training bench. Two mower configurations were tested: 6.55 cm3 rev(-1) (0.4 in.3 rev(-1)) displacement motor with a 0.748 kg blade and 47.5 cm3 rev(-1) (2.9 in.3 rev(-1)) displacement motor with a 9.4 kg blade. A PTO-driven rotary mower was not used to test the circuit due to spatial and safety limitations of the hydraulic training bench. Results from the first mower configuration verified the concepts behind the hydraulic circuit. The second configuration verified the OPSS and indicated the applicability of the circuit to a rotary mower.  相似文献