CCNU in the treatment of canine epitheliotropic lymphoma     

Williams LE  Rassnick KM  Power HT  Lana SE  Morrison-Collister KE  Hansen K  Johnson JL 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2006,20(1):136-143

This retrospective study examined the use of CCNU (1-[2-chloroethyl]3-cyclohexyl-1-nitrosurea) in 36 dogs with epitheliotropic lymphoma. Thirty-one (86%) dogs had the cutaneous form of disease, and 5 (14%) dogs had the oral form of disease. Nineteen (51%) dogs were treated with other chemotherapeutic agents before receiving CCNU. All dogs had detectable disease at the time CCNU therapy was initiated. Dogs received a median starting CCNU dosage of 70 mg/m2 (range, 50-100 mg/m2). The median number of treatments administered was 3 (range, 1-12 treatments). After the initial treatment, the CCNU dosage was adjusted in 9 of 26 (35%) dogs in which CCNU was continued: 7 had dosage reductions, and 2 had dosage escalations. Twenty-eight of 36 (78%) dogs had a measurable response to CCNU for a median duration of 106 days (95% confidence interval [CI], 75-182). Six dogs (17%) had a complete response, including 5 dogs with the cutaneous form and 1 dog with the oral form. Twenty-two dogs (61%) had a partial response, including 20 dogs with the cutaneous form and 2 dogs with the oral form, for a median duration of 88 days (95% CI, 62-170). Toxicoses after CCNU chemotherapy included myelosuppression in up to 29% of the dogs, gastrointestinal signs in up to 22% of the dogs, and liver enzyme activity increases in up to 86% of the dogs. This study demonstrates that CCNU chemotherapy can be considered a reasonable option for the treatment of canine epitheliotropic lymphoma in dogs.  相似文献   

Molecular characterisation and analysis of bovine rotavirus strains circulating in Ireland 2002-2004     

Reidy N  Lennon G  Fanning S  Power E  O'Shea H 《Veterinary microbiology》2006,117(2-4):242-247

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Ecological influences on the difference in δ15N and δ13C values between fish tissues: implications for studies of temporal diet variation     

Wendy K. Michaud  J. Brian Dempson  James D. Reist  Michael Power 《Ecology of Freshwater Fish》2013,22(4):520-529

Temporal diet changes can be detected by comparing δ¹³C and δ¹⁵N values between tissues with different isotopic turnover times. However, other factors contribute to disparities in δ¹³C and δ¹⁵N signatures between tissues and could confound the interpretation of stable isotope data. We examined the effects of ecological factors on differences in muscle and liver δ¹³C and δ¹⁵N signatures of Arctic charr [Salvelinus alpinus, (L.)] to determine whether their effects were large enough to influence studies of diet change. In addition, we examined whether differences in lipid content accounted for a significant portion of the differences in δ¹³C values between tissues. Results indicated that life history, diet, reproductive status and gender had significant effects on the differences in δ¹³C values between tissues, while gender and diet significantly affected differences in δ¹⁵N values. Differences in % lipid content between tissues also explained approximately 74% of the observed variation in the difference in δ¹³C values between tissues. The differences in δ¹³C values observed between muscle and liver tissues may be partially explained by physiological differences in lipid storage and use between tissues associated with ecological factor effects. These results demonstrate that ecological factors other than a change in diet can influence the differences in δ¹³C and δ¹⁵N signatures between muscle and liver tissues. However, the impact of ecological factors on studies of diet change depends on how the magnitude of the factor effects compared with a biologically meaningful change in diet.  相似文献   

The phenotypic characterisation of R2 generation transgenic rice plants under field and glasshouse conditions     

P. T. Lynch  J. Jones  N. W. Blackhall  M. R. Davey  J. B. Power  E. C. Cocking  M. R. Nelson  D. M. Bigelow  T. V. Orum  C. E. Orth  W. Schuh 《Euphytica》1995,85(1-3):395-401

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Hybridization, Through Culture of Embryos and Immature Seeds, of a Range of Tomato Cultivars with a Tomato Somatic Hybrid [Lycopersicon esculentum (+) L. peruvianum]: Emergence of a Possible New Marker Gene for Tomato Breeding     

R. S. Paul    M. Latif    F. B. D'Utra Vaz  M. R. Davey  J. B. Power 《Plant Breeding》1993,111(4):273-282

Two hexaploid somatic hybrids [Sh; L. esculentum (+) L. Peruvianum] accessions 6 and 18 were back-crossed with two diploid L. Esculentum cultivars ‘Moneymaker’ (mm) and ‘pusa Ruby’ (pr). Twenty-two plants of the bc2 generation were produced by backcrossing 7 bcl plants (mm x sh, 6, 18) with five tomato cultivars. Fourteen of the bc2 plants were self-fertile, five produced anther cones with anthocyanin pigmentation not present in the parents. A bc3 generation was developed by crossing the four cultivars as female parent with three bc2 generation plants. The bc3 progeny derived from one pollen parent plant were produced without the need to culture immature seeds. They segregated with respect to pigmented anther cones and were self-fertile. The anther cone pigmentation of the pollen parent plant was associated with increased seed set, greater fruit size and an orange-red fruit colour. These features were transmitted to the fertile bc3 generation. Conversely, bc3 offspring involving the other two parent plants were only recovered by culture of immature seeds. The recovery of diploid plants in BCl and self-fertility in BC2 resulted in almost total recovery of the tomato cultivar characteristics (fruit size, colour and number of seeds) by BC3.  相似文献   

The embryogenic potential of rice cell suspensions affects their recovery following cryogenic storage     

P. T. Lynch  E. E. Benson  J. Jones  E. C. Cocking  J. B. Power  M. R. Davey 《Euphytica》1955,85(1-3):347-349

Summary The rates of recovery from cryogenic storage of suspension cultures of the Japonica rice cultivar Taipei 309, as determined by the reduction of triphenyl tetrazolium chloride and cell regrowth, were significantly influenced by the embryogenic potential of the non-frozen cultures.  相似文献   

From risk assessment to sediment management an international perspective   总被引：1，自引：1，他引：1  

Sabine E. Apitz  Elizabeth A. Power 《Journal of Soils and Sediments》2002,2(2):61-66

Contaminated sediment management is complex and multivariate, involving a careful balance of science, politics and economics. As is true for most such complex issues, there is not a single correct way to address a problem, but rather the approach should be driven by the ecological, political and economic goals of all interested parties. However, because the choices made have far-reaching implications, it is useful for countries, regions or communities to develop standard approaches for sediment assessment and management to meet agreed-upon goals. This paper provides a brief review of a number of sediment assessment frameworks from around the world. Their main similarities and differences, and some of the reasons behind them, are addressed. Aspects of assessing and managing sediments are discussed, as well as why these are (or should be) driven by sediment management goals. Finally, suggestions are made to support the development of a European framework for sediment management and environmental quality. This paper was originally an invited address for the Risk Management and Communication Workgroup WG5 at the European Sediment Research Network (SedNet) Inaugural Conference, Venice, Italy, April 22–23, 2002  相似文献   

Growth and Survival of the Blood Ark Anadara ovalis (Bruguière, 1789) Cultured in Mesh Bags on Soft-Bottom Sediments in the Coastal Waters of Georgia     

Alan J.  Power Randal L.  Walker 《Journal of the World Aquaculture Society》2001,32(3):269-277

Annual growth and survival rates were measured for blood arks Anadara ovalis (Bruguière 1789) cultured in mesh bags that were placed at the spring-low-water mark in soft-bottom sediments of the Skidaway River, Georgia. The feasibility of growing the arks to a marketable size using this technique was assessed by determining the effects of stocking density and biofouling on growth and survival. Two replicate densities of 190 (low) and 400 (high) arks per mesh bag (mean shell length 31.97 mm) were planted in early September 1999. In April 2000, the arks cultured at the lower density had a significantly larger size (44.99 mm) than at the higher density (43.83 mm), with growth rates of 1.85 mdmo, and 1.69 mm/mo, respectively. Growth decreased considerably in the subsequent months (low: 0.17 mm/mo; high: 0.30 mm/mo). There was no significant difference in ark size between treatments after a year's growth in late August 2000 (low: 45.76 mm, 1.15 mm/mo; high: 45.31 mm, 1.11 mm/mo). Similarly, no significant difference in annual survival rates between stocking densities occurred (low: 42.89%; high: 40.25%). The present findings indicate that this method of growing arks to market size has potential to contribute to future endeavors to develop an aquaculture fishery for the blood ark in the coastal waters of Georgia.  相似文献   

Nitrification in paleocene shale     

Power JF  Bond JJ  Sandoval FM  Willis WO 《Science (New York, N.Y.)》1974,183(4129):1077-1079

Exchangeable ammonium nitrogen is present in Paleocene (Fort Union) shale below a depth of 10 meters in North Dakota and eastern Montana. Above 10 meters, exchangeable ammonium nitrogen is nitrified in situ. The lack of viable nitrifying organisms and the probable lack of oxygen prevent in situ nitrification below 10 meters. Shale samples incubated at 27 degrees C under nonsterile conditions or shales exposed to atmospheric contamination exhibited active nitrification without additional treatment.  相似文献   

对旋耕机排刀和定位的再认识     

史洪涛  齐双丽  黄爱武 《拖拉机与农用运输车》2011,38(4):86-88

针对旋耕机刀轴断裂问题,分析我厂产品与市场成熟产品的异同,针对耕作实际和配套通用性,构造合理排刀的数学模型和MATLAB程序,通过人机对话,实现排刀方案多选和优选。  相似文献