Acute cortisol responses of lambs castrated and docked using rubber rings with or without a castration clamp     

AS DINNIS  KJ STAFFORD  DJ MELLOR  RA BRUCE  RN WARD 《Australian veterinary journal》1997,75(7):494-496

Objective To measure the plasma cortisol response in lambs castrated and docked by three different methods (ring castration and tail docking, ring and clamp castration and tail docking; ring and clamp castration and ring tail docking) for 4 h after treatment.
Design A physiological study with controls.
Procedure A rubber ring was applied to the scrotum. Then the castration clamp was placed, distal to the ring, on each spermatic cord such that there was no overlap of the crush lines.
Results There were no differences in the cortisol secretion of the lambs castrated and tail docked by the ring only and by the ring plus castration clamp methods. Using the castration clamp in addition to the ring on the tail had no effect on cortisol secretion.
Conclusions Using the castration clamp did not appear to reduce the cortisol response to ring castration and docking, as demonstrated elsewhere, because the areas of uncrushed tissue between the two castration clamp crush lines allowed nociception from ischemic scrotal tissue to be transmitted cranially via undamaged nerve fibers.  相似文献   

Identification of Brucella ovis in formalin-fixed paraffin-embedded genital tissues of naturally infected rams by the indirect peroxidase-antiperoxidase technique   总被引：1，自引：0，他引：1  

RA FOSTER  PW LADDS  D. HOFFMANN  LJ GLEESON 《Australian veterinary journal》1988,65(10):324-326

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Isolation of an intrinsic precursor to molecular chemisorption     

DE Brown  DJ Moffatt  RA Wolkow 《Science (New York, N.Y.)》1998,279(5350):542-544

Over the past 70 years, numerous gas-surface adsorption studies have indicated the existence of a weakly bound, mobile intermediate that is a precursor to chemical bond formation. The direct observation and characterization of such a species are presented. Precursor and chemisorbed benzene on a silicon surface were clearly distinguished with the use of a tunable-temperature scanning tunneling microscope. Precursor decay to chemisorption was observed, allowing the salient features of the potential energy surface to be determined.  相似文献   

Linking Policy and Outcomes: A Simulation Model of Poverty Incidence     

ELIZABETH E. DAVIS  BRUCE A. WEBER 《Growth and change》1998,29(4):423-444

ABSTRACT Many states are striving to meet public demand for accountability by “benchmarking”—setting social goals for the state and tracking progress in meeting the goals. However, states are finding it difficult to set realistic targets and to assess the impacts of policy on achievement of the targets without a framework that models the relationships among policy targets, policy actions and social and economic forces outside the control of policymakers. This paper develops a dynamic simulation model of one “benchmark” (poverty incidence) in Oregon, linking transitions into and out of poverty to various events (increased earnings, or having a child as a teenager, for example), and linking these events to policy. The simulation results suggest that, with current policies, Oregon will come close to achieving its poverty benchmark target of 11 percent by the year 2000 if economic conditions remain favorable. The model is used to examine the impact on poverty incidence of three policy strategies: reducing high school dropout and teen pregnancy rates, increasing the effectiveness of social support programs to JOBS participants, and boosting job growth. The simulation results suggest that when assessing the state's performance or “grading” the observed trend in the poverty benchmark, policymakers should take into account the performance of the state (and national) economy. The impact of policy efforts to reduce poverty is limited because many poverty spells are caused largely by events not affected by current state policies.  相似文献   

Indigofera spicata (creeping indigo) poisoning of three ponies     

SM Ossedryver  GI Baldwin  BM Stone  RA McKenzie  AW van Eps  S Murray  MT Fletcher 《Australian veterinary journal》2013,91(4):143-149

Three ponies continuously grazed a pasture containing an estimated 24% Indigofera spicata (wet weight basis) for 4–6 weeks in April and May 2004. They developed ataxia, paresis, depression, muscle fasciculations, dysphagia, ptyalism and halitosis. Two also developed corneal opacity. One pony recovered with supportive treatment, but the other two were euthanased and necropsied. Neuropathology was not present in either case, but both livers had periacinar and periportal lymphocytic infiltrations and hydropic degeneration of mid‐zonal hepatocytes, with mild to moderate periacinar necrosis also evident in one. The I. spicata contained 2.66 mg 3‐nitropropionic acid (3‐NPA)/g dry matter and 1.5 mg indospicine/g dry matter. Indospicine, but not 3‐NPA, was detected in serum from both of the euthanased ponies and indospicine was detected in heart, liver and muscle from the one pony in which this assay was performed. The clinical syndrome closely resembled ‘Birdsville horse disease’ caused by I. linnaei and was similar to that reported in horses poisoned by the closely related species I. hendecaphylla and to 3‐NPA poisoning of other animals, including humans. 3‐NPA is thought to cause this neurological syndrome. To our knowledge, this is the first authenticated report of I. spicata poisoning in grazing animals. We also report here the first published evidence that 3‐NPA and indospicine exist in naturalised I. spicata in Australia and of the formation of indospicine residues in tissues of animals grazing paddocks infested with I. spicata.  相似文献   

Re: Perpetrator‐induced traumatic stress     

RA Bradley 《Australian veterinary journal》2013,91(4):120-120

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Management of respiratory failure from tick paralysis     

RA Webster  S Haskins  B Mackay 《Australian veterinary journal》2013,91(12):499-504

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An automated in-line clinical mastitis detection system using measurement of conductivity from foremilk of individual udder quarters     

RW Claycomb  PT Johnstone  GA Mein  RA Sherlock 《New Zealand veterinary journal》2013,61(4):208-214

AIM: To assess a novel method for automatic in-line detection of clinical mastitis.

METHODS: For a brief period at the start of milking for each cow, electrical conductivity of foremilk was measured for each quarter in turn, using a single sensor installed in the long milk tube (LMT) about 1.5 m downstream from the milking-machine claw. Sequential separation of flow between udder quarters was achieved by control of pulsation to individual teatcups within a conventional cluster. The ratio of conductivity values between quarters was used as an indicator of mastitis status. The concept was evaluated initially in a pilot trial in a 200-cow herd milked in a 23-stall swing-over herringbone milking parlour. It was then tested rigorously in a field trial in a 640-cow herd milked in a 50-stall rotary milking parlour. Both trials were conducted in the Waikato region of New Zealand. In the latter trial, sensor results were compared with visual inspection of a commercial in-line mastitis filter fitted to each milking unit. These filters were inspected for clots immediately after every cow's milking, for 3 weeks. The dataset of approximately 27,000 individual milkings was tested against several published or potential alter- native ‘gold standards’ for diagnosing clinical mastitis.

RESULTS: In the pilot trial, 12–14 clinical events were detected out of 19 true clinical quarters, with a false-alert rate of between three and five false electrical-conductivity alerts per 1,000 individual milkings. In the more rigorous field trial, sensitivity ranged from 68 to 88%, and the false-alert rate (false-alert episodes per 1,000 individual milkings) ranged from 2.3 to 7.0.

CONCLUSION: The novel clinical mastitis detection system, based on separation of the flow and measurement of electrical conductivity from foremilk of individual udder quarters, has the potential to provide a new tool for helping farmers to monitor clinical mastitis in herds milked with conventional clusters.  相似文献   

Effect of dry period length on the effect of an intramammary teat sealant on the risk of mastitis in cattle treated with antibiotics at drying off     

RA Laven  CC Balcomb  WT Tulley  KE Lawrence 《New Zealand veterinary journal》2013,61(4):214-220

AIM: The aim of this study was to evaluate, under farm conditions, the use of a teat sealant in addition to whole herd dry cow antibiotic therapy on the risk of clinical mastitis in dairy cattle at pasture, and to evaluate the impact of dry period length on that risk and the impact of the teat sealant on that risk.

METHODS: Dairy cows in three herds which used routine whole herd antibiotic therapy were randomly assigned to receive either treatment with an internal teat sealant (n=322) or no additional treatment (n=313) at drying-off between March and May 2010. All clinical mastitis cases during the dry period and to the end of the subsequent lactation were recorded by farm staff; factors affecting risk of clinical mastitis were then analysed using a Cox proportional hazards model.

RESULTS: Median duration of the dry period was 112 days with >25% of cows having a dry period >130 days. The incidence risk of mastitis during lactation for cows treated with teat sealant was 9.9 (95% CI=6.9–13.7) cases per 100 cows compared with 17.9 (95% CI=13.8–22.6) cases per 100 cows for cows treated with antibiotic alone. The addition of a teat sealant to dry cow antibiotic therapy decreased the risk of clinical mastitis only in the first 33 days after calving (Hazard risk 0.24 (95% CI=0.12–0.48)). Length of dry period did not significantly affect the risk of clinical mastitis, or the effect of adding teat sealant to dry cow antibiotic therapy on the risk of clinical mastitis.

CONCLUSIONS: In these herds where, based on the mastitis history, whole herd antibiotic therapy had been recommended, the use of a teat sealant significantly reduced the risk of clinical mastitis. This effect was limited to the first 33 days after calving; subsequently there was no significant effect of treatment. There was no effect of dry period length on risk of clinical mastitis, nor any significant interaction with treatment.

CLINICAL RELEVANCE: Combination therapy with teat sealant and antibiotic was effective under New Zealand conditions in herds using whole herd antibiotic treatment at drying off. Teat sealant reduced risk of clinical mastitis in cattle with dry periods substantially longer than 100 days, and there was no evidence that this effect changed as dry period length increased.  相似文献   

A lymphoproliferative disease in Manx cats with similarities to autoimmune lymphoproliferative syndrome (ALPS) in people     

D Aberdein  JS Munday  KG Thompson  RA Fairley 《New Zealand veterinary journal》2013,61(3)

In 2009–2010, an unusual lymphoproliferative disease was identified in multiple siblings from successive litters of Manx cats, suggesting a genetic predisposition to development of this disease. Presentation of disease in the cats had multiple similarities with the human disease ALPS, a rare inherited disorder that causes persistent lymphoproliferation, together with variable manifestations of autoimmunity and increased susceptibility to neoplasia. The majority of human ALPS patients have inherited Fas gene mutations, causing defective apoptosis of lymphocytes, although for a proportion of ALPS patients the underlying genetic mutations remain unknown. In order to identify the likely mode of inheritance of the disease, further matings of potential carrier cats are in progress. Studies to investigate the potential role of abnormalities in the Fas gene in the development of the disease in cats are also proposed. Identifying and further characterising the nature and mechanism of the disease in cats may allow better understanding of the development, progression, and treatment of ALPS in humans.  相似文献