Mortalities in Atlantic salmon, Salmo salar L., associated with pathology of the melano-macrophage and haemopoietic systems     

R. PALMER  R. H. SOUTAR  E. J. BRANSON  P. J. SOUTHGATE  E. DRINAN  R. H. RICHARDS  R. O. COLLINS 《Journal of fish diseases》1992,15(2):207-210

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The in vitro susceptibility of Aeromonas salmonicida and other fish-pathogenic bacteria to 29 antimicrobial agents   总被引：4，自引：0，他引：4  

V. INGLIS  R. H. RICHARDS 《Journal of fish diseases》1991,14(6):641-650

Abstract. The minimum inhibitory concentrations (MICs) of 29 antimicrobial agents were determined for some representative Aeromonas salmonidda, Yersinia ruckeri and Vibrio isolates. Eleven of them, including three widely used in clinical practice, were further tested against 28–36 recent field isolates of A. salmonidda. The fluoroquinolones were inhibitory at very low concentrations with 50% of A. salmonidda isolates having a MIC of enro-floxacin ≤0·02μg ml-1. The distribution of MICs to the fluoroquinolones and to oxolinic acid were similar indicating possible cross resistance. Amoxycillin, florfenicol, minocycline, rifampicin and the potentiated sulphonamides had a single peak MIC distribution with values of ≤1·25μg ml-1. Minimum inhibitory concentrations of the fluoroquinolones were four or more times greater at 10°C compared with 22°C; this was not so with amoxycillin, florfenicol or the sulphachlorpyridazine-trimethoprim (S-TP) combination. A. salmonicida was rapidly killed at 22°C by the fluoroquinolones and S-TP whereas oxolinic acid and amoxycillin killed within 24h. Florfenicol was bacteriostatic. The therapeutic potential of some of these antibiotics is considered.  相似文献   

Spirometra erinacei / S. erinaceieuropaei in a feral cat in Manawatu with chronic intermittent diarrhoea     

CE Ugarte  DG Thomas  RB Gasser  M Hu  I Scott  MG Collett 《New Zealand veterinary journal》2013,61(5):347-351

CASE HISTORY: A feral cat captured in the Manawatu region of New Zealand was treated for worms and fleas, and kept confined in a metabolic cage. It showed good appetite and weight gain but had intermittent watery, yellow diarrhoea.

CLINICAL FINDINGS: Clinical examination under sedation was unremarkable and routine blood tests showed no significant abnormalities. The cat was negative for feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV). Different canned cat foods did not alter the course of the diarrhoea, and the cat was euthanised 6 months after capture. At necropsy, two sections of adult Spirometra tapeworms were found in the jejunum and typical Spirometra eggs were found in colonic contents. Molecular identification of the parasite was undertaken, using the cytochrome- c oxidase subunit-1 gene (cox1) sequence.

DIAGNOSIS: Chronic intermittent diarrhoea associated with Spirometra erinacei / S. erinaceieuropaei infection.

CLINICAL RELEVANCE: Spirometra has not been reported in New Zealand before but has been associated with gastrointestinal disease in cats in other parts of the world. It requires speciestargeted treatment to be eliminated effectively, and is zoonotic. Diagnosis could be diffi cult for clinicians who are not familiar with the parasite and its life cycle.  相似文献   

Alfaxalone compared with ketamine for induction of anaesthesia in horses following xylazine and guaifenesin     

Helen L Keates  Andrew W van Eps  Martin RB Pearson 《Veterinary anaesthesia and analgesia》2012,39(6):591-598

ObjectiveTo compare anaesthesia induced with either alfaxalone or ketamine in horses following premedication with xylazine and guaifenesin.Study designRandomized blinded cross-over experimental study.AnimalsSix adult horses, five Standardbreds and one Thoroughbred; two mares and four geldings.MethodsEach horse received, on separate occasions, induction of anaesthesia with either ketamine 2.2 mg kg^?1 or alfaxalone 1 mg kg^?1. Premedication was with xylazine 0.5 mg kg^?1 and guaifenesin 35 mg kg^?1. Incidence of tremors/shaking after induction, recovery and ataxia on recovery were scored. Time to recovery was recorded. Partial pressure of arterial blood oxygen (PaO₂) and carbon dioxide (PaO₂), arterial blood pressures, heart rate (HR) and respiratory rates were recorded before premedication and at intervals during anaesthesia. Data were analyzed using Wilcoxon matched pairs signed rank test and are expressed as median (range).ResultsThere was no difference in the quality of recovery or in ataxia scores. Horses receiving alfaxalone exhibited a higher incidence of tremors/shaking on induction compared with those receiving ketamine (five and one of six horses respectively). Horses recovered to standing similarly [28 (24–47) minutes for alfaxalone; 22 (18–35) for ketamine] but took longer to recover adequately to return to the paddock after alfaxalone [44 (38–67) minutes] compared with ketamine [35 (30–47)]. There was no statistical difference between treatments in effect on HR, PaO₂ or PaCO₂ although for both regimens, PaO₂ decreased with respect to before premedication values. There was no difference between treatments in effect on blood pressure.Conclusions and clinical relevanceBoth alfaxalone and ketamine were effective at inducing anaesthesia, although at induction there were more muscle tremors after alfaxalone. As there were no differences between treatments in relation to cardiopulmonary responses or quality of recovery, and only minor differences in recovery times, both agents appear suitable for this purpose following the premedication regimen used in this study.  相似文献   

The humoral response in natural Dirofilaria immitis infections in dogs     

K. TANAKA  RB ATWELL 《Australian veterinary journal》1991,68(12):396-399

Plasma samples from dogs with infections of Dirofilaria immitis were assessed using ELISA and Western blotting techniques. These results were then assessed in relation to age and sex of the host, and to the numbers of microfilariae and adult filariae. Dogs with microfilariae tended to have lower levels of infection. In infected dogs, mean ELISA titres increased directly with the degree of infection. Dogs that were either young or mildly infected, showed a preferential antibody reactivity to antigens in the high molecular weight regions of the immunoblots. With increasing age and/or the extent of infection, an antibody response to antigens in the low molecular weight regions was apparent.  相似文献   

Ovine congenital progressive muscular dystrophy: mode of inheritance     

R B RICHARDS  R P LEWER  I K PASSMORE  N C McQUADE 《Australian veterinary journal》1988,65(3):93-94

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Thermal,hematological, and serological responses of weanling horses following inoculation with equine abortion virus: its similarity to equine influenza     

DOLL ER  WALLACE E  RICHARDS MG 《The Cornell veterinarian》1954,44(2):181-190

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Complement-fixation reactions in equine virus abortion     

DOLL ER  MCCOLLUM WH  WALLACE ME  BRYANS JT  RICHARDS MG 《American journal of veterinary research》1953,14(50):40-45

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A study of the anesthetic properties of combinations of hexobarbital sodium and thialbarbitone sodium in dogs     

WEAVER LC  BURCH GR  ABREU BE  RICHARDS AB 《American journal of veterinary research》1958,19(73):940-942

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The potential for occupational exposure of veterinarians to ketamine resulting in positive drug tests          下载免费PDF全文

RB Cope 《Australian veterinary journal》2018,96(3):59-61

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