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41.
The aim of this study was to determine the neuronal responses following insulin administration during the late follicular phase. Intact ewes were given either saline or insulin (5 IU/kg, i.v.) at 35 h after progesterone withdrawal and killed 3 h later. There was a marked increase in the number of Fos‐positive noradrenergic neurones in the caudal brainstem of insulin‐treated ewes. In the hypothalamic paraventricular nucleus, insulin treatment increased the presence of Fos‐positive corticotrophin‐releasing hormone neurones (from 2% to 98%) and Fos‐positive arginine vasopressin parvocellular neurones (from 2% to 46%). Interestingly, after insulin treatment, despite a general increase in Fos‐positive neurones in the arcuate nucleus (ARC), there was a marked reduction (from 47% to 1%) in Fos‐positive β‐endorphin neurones. Similarly, colocalized Fos and oestradiol receptor (ER) α‐positive neurones decreased in the ARC after insulin (from 7% to 3%). Conversely, in the ventromedial nucleus, ERα‐positive neurones with Fos increased (from 7% to 22%) alongside a general increase in Fos‐positive neurones. Overall, a complex system of neurones in brainstem and hypothalamus is activated following insulin administration during the late follicular phase. 相似文献
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Studies were made at Presque Isle, Maine, 1962–1966, to determine the suppressive effects of several materials against spread of the potato leaf roll cirus,Corium solani Holmes, transmitted by the green peach aphid,Myzus persicae (Sulzer), when applied as foliar sprays to Kennebec, Green Mountain, or Chippewa potatoes in field cages or in field plots. The early cage tests showed that spray mixtures containing 1% of the systemic plant growth regulant chlorocholine chloride (2-chloroethyltri-methylammonium chloride) or 1% of mineral oil were more effective than the insect antifeeding compound AC-24,055® (=ENT-25,651), the aphid-repellent compounds ENT 20,430 or ENT 21,178, or the surfactants Sarkosyl-O® (bis (2-ethylhexyl) sodium sulfosuccinate) or Aerosol-OT® (CH3 (CH2)n CON (CH3) CH2 COOH). Field tests disclosed that chlorocholine chloride at 5.2 lb or 2.6 lb/a/a was more effective when healthy green peach aphids were placed on infector plants in the plots soon after the plants were sprayed, 1 week later, or soon after the 2nd of 2 weekly applications than when the aphids were introduced before spraying. The difference in leaf roll suppression at these two dosages was not significant at the 5% level; as high as 90% control of leaf-roll spread was obtained. When only natural infestations of aphids were involved and field spread of the virus was light, the 86% control of leaf roll spread that was obtained from 4 weekly applications made in late June and in July was not significantly different (P=0.05) from the 79% control obtained from 2 biweekly applications made during the same period of time. The potato plants soon recovered from the slight chlorosis resulting from the spray treatment and there was no reduction in weight of US 1 tubers at harvest. Aphid population trends in treated plots were not affected. 相似文献
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