Canine Clinical Parasitology     

RM Barlow 《Australian veterinary journal》1994,71(6):190-190

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Firocoxib efficacy preventing urate-induced synovitis, pain, and inflammation in dogs     

Drag M  Kunkle BN  Romano D  Hanson PD 《Veterinary therapeutics : research in applied veterinary medicine》2007,8(1):41-50

This positive-control study evaluated the efficacy of firocoxib versus carprofen, deracoxib, and meloxicam for the prevention of pain and inflammation in a urate crystal synovitis model of lameness. Lameness scoring and force plate gait analysis were used to assess efficacy. The resulting lameness scores and force plate ground reaction forces after urate crystal injection were not significantly different among the groups. Relative to each group's baseline (nonlame) score, only the firocoxib group was not significantly lame, based on lameness score, at the model's peak effect.  相似文献   

Variation in the immuno-pathological responses of lambs after experimental infection with different strains of Mycobacterium avium subsp. paratuberculosis     

Verna AE  Garcia-Pariente C  Muñoz M  Moreno O  García-Marin JF  Romano MI  Paolicchi F  Pérez V 《Zoonoses and public health》2007,54(6-7):243-252

Ruminant infection by Mycobacterium avium subsp. paratuberculosis (MAP) causes a granulomatous inflammatory response in the intestine and associated lymph nodes. Differences either in the affected organs or in the inflammatory infiltrate were observed between species and individuals. Such differences are usually attributed to variations in host immune responses or to inconsistent effects among different MAP strains. To evaluate if different MAP strains induce different immuno-pathological responses in lambs, 28 one-month-old individuals were divided into six groups and inoculated with different MAP strains. Groups 1 and 2 were inoculated with two bovine strains isolated in Argentina that showed different genetic patterns after BstEII-IS900-RFLP (hereafter strains E and A respectively). Group 3 was inoculated with a bovine strain isolated in Spain obtained after a previous step of culture (patterns C1). Group 4 was inoculated with a homogenate of intestinal mucosa of a clinical case affected by the same bovine strain as that of group 3. Group 5 was inoculated with an ovine strain that was directly purified from the intestinal mucosa of a clinical case, and group 6 was kept as control (i.e. no inoculation). Peripheral immune responses were assessed until 150 days post-infection (dpi), when lambs were humanely killed. Pathological studies were performed in tissues from the intestine and lymph nodes. Lesion types and inflammatory infiltrates were examined as indicators of pathogenicity. All the lambs infected with bovine MAP strains showed a common lesion pattern regardless of the strain type. Such pattern was characterized by focal lesions mainly in the mesenteric lymph nodes, the presence of fibrous tissue, and, occasionally, necrosis in the granulomas as well as the presence of numerous giant cells. Differences in lesion severity were observed among groups: lambs from groups 1 and 2 had the highest number of granulomas and the largest lymph node area affected. Lesions in animals from group 5 (infected with an ovine strain) were more severe and occurred mostly in the intestinal lymphoid tissue; necrosis, fibrosis or giant cells were never detected in this group. These results indicate that the MAP strain type induces different pathological responses in lambs.  相似文献   

Safety and functional outcomes associated with short-term rehabilitation therapy in the post-operative management of tibial plateau leveling osteotomy     

Laura S. Romano  James L. Cook 《The Canadian veterinary journal. La revue veterinaire canadienne》2015,56(9):942-946

This retrospective cohort study using electronic questionnaires compared the perioperative complication rates of tibial plateau levelling osteotomy (TPLO) surgery and the 8-week, 6-month, and 1-year functional outcomes, between rehabilitation and traditional post-operative management. Dogs were placed into 1 of 2 cohort groups based on attending veterinarian’s selected management: i) “traditional” involving restriction to cage rest and leash walking, and ii) “rehabilitation” performed by a certified practitioner. There was no statistically significant difference in complication rates in the perioperative period between the 2 treatment cohorts (P > 0.1). The rehabilitation group was 1.9 times more likely to reach full function at 8 wk (P = 0.045). Conversely, the traditional group was 2.9 times more likely be categorized as having unacceptable function at 8 wk after surgery (P = 0.05). This study suggests that rehabilitation performed by a certified practitioner is safe and may improve short-term outcomes when used in the initial postoperative management for dogs treated with TPLO.  相似文献   

Evaluation of an Immunochromatographic Test to the Diagnosis of Canine Brucellosis Caused by Brucella canis          下载免费PDF全文

LB Keid  JA Diniz  TMFS Oliveira  HL Ferreira  RM Soares 《Reproduction in domestic animals》2015,50(6):939-944

This study evaluated the performance of an immunochromatographic test (ICT) for the diagnosis of canine brucellosis caused by Brucella canis, comparing its results with that of the rapid slide agglutination test with and without the use of 2‐mercaptoethanol and the agar gel immunodiffusion test (AGID). The microbiological culture, PCR and clinical examination were used as reference. According to the results obtained in clinical examination, blood culture, culture of semen and vaginal swab and PCR in blood, semen and vaginal swab, a total of 102 dogs were divided into three groups: B. canis‐infected dogs (Group 1), B. canis‐non‐infected dogs (Group 2) and dogs with suspected brucellosis (Group 3). The diagnostic sensitivity of RSAT, 2ME‐RSAT, AGID and ICT in Group 1 was, respectively, 75%, 37.5%, 27.8% and 89.58%. The diagnostic specificity of RSAT, 2ME‐RSAT, AGID and ICT in Group 2 was, respectively, 91%, 100%, 100%, and 100%. In dogs with suspected brucellosis, 9.67% were RSAT positive, none was positive by 2ME‐RSAT, 3.22% were AGID positive and 6.45% were ICT positive. The main drawback concerning canine brucellosis diagnosis is the lack of a highly sensitive serological assay to be used as a screening test to the rapid identification of infected animals. The ICT showed a high diagnostic specificity and a diagnostic sensitivity value greater than that observed in the RSAT, 2ME‐RSAT and AGID. However, 10.41% of infected dogs had negative results by ICT. These dogs were positive by microbiological culture and/or PCR, indicating active infection and consequently a higher potential of spreading Brucella. Although rapid and simple to perform, the ICT lacked sensitivity to be used as a screening test.  相似文献   

Molecular Response to Toxic Diatom-Derived Aldehydes in the Sea Urchin Paracentrotus lividus     

Stefano Varrella  Giovanna Romano  Adrianna Ianora  Matt G. Bentley  Nadia Ruocco  Maria Costantini 《Marine drugs》2014,12(4):2089-2113

Diatoms are dominant photosynthetic organisms in the world’s oceans and represent a major food source for zooplankton and benthic filter-feeders. However, their beneficial role in sustaining marine food webs has been challenged after the discovery that they produce secondary metabolites, such as polyunsaturated aldehydes (PUAs), which negatively affect the reproductive success of many invertebrates. Here, we report the effects of two common diatom PUAs, heptadienal and octadienal, which have never been tested before at the molecular level, using the sea urchin, Paracentrotus lividus, as a model organism. We show that both PUAs are able to induce teratogenesis (i.e., malformations), as already reported for decadienal, the better-studied PUA of this group. Moreover, post-recovery experiments show that embryos can recover after treatment with all three PUAs, indicating that negative effects depend both on PUA concentrations and the exposure time of the embryos to these metabolites. We also identify the time range during which PUAs exert the greatest effect on sea urchin embryogenesis. Finally, we report the expression levels of thirty one genes (having a key role in a broad range of functional responses, such as stress, development, differentiation, skeletogenesis and detoxification processes) in order to identify the common targets affected by PUAs and their correlation with morphological abnormalities. This study opens new perspectives for understanding how marine organisms afford protection from environmental toxicants through an integrated network of genes.  相似文献   

Grapevine anthracnose in berries causes biochemical and enzymatic alterations     

Modesto  Lenon Romano  de Almeida  Anna Flávia Neri  Steiner  Daniel Ricardo Maass  Ribeiro  César Freitas  Nodari  Rubens Onofre  Welter  Leocir José  da Silva  Aparecido Lima 《European journal of plant pathology / European Foundation for Plant Pathology》2022,163(3):695-706

European Journal of Plant Pathology - Anthracnose (Elsinöe ampelina) is a major fungal disease in humid regions, causing damage to grapevine berries and decreasing fruit quality. Studies...  相似文献   

Use of transesophageal echocardiography for visualization of the patent ductus arteriosus during transcatheter coil embolization     

Romain Pariaut DMV  N Sydney Moïse DVM  MS  Marc S Kraus DVM  Anna RM Gelzer Dr.med.vet.  Mark Rishniw BVSc  MS  James A Flanders DVM  Shari Renaud-Farrell VT  Mary Ellen Charter VT 《Journal of Veterinary Cardiology》2004,6(1):32-39

Transesophageal echocardiography (TEE) enhances our ability to see the patent ductus arteriosus in the dog. The improved visualization may potentially improve our ability to perform transcatheter coil embolization in patients that are more likely to have a successful outcome. This report uses still and video images to detail the specifics of coil embolization as performed with the assistance of TEE and compares the images with those of angiography, surgery and postmortem examination.  相似文献   

The Lipid A from the Haloalkaliphilic Bacterium Salinivibrio sharmensis Strain BAGT     

Sara Carillo  Giuseppina Pieretti  Buko Lindner  Ida Romano  Barbara Nicolaus  Rosa Lanzetta  Michelangelo Parrilli  Maria Michela Corsaro 《Marine drugs》2013,11(1):184-193

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The Effect of Probiotics in a Litopenaeus vannamei Biofloc Culture System Infected with Vibrio parahaemolyticus     

Dariano Krummenauer  Luis Poersch  Luiz A. Romano  Gabriele R. Lara  Pedro Encarnação 《Journal Of Applied Aquaculture》2013,25(4):370-379

We analyzed the effect of commercial bacterial probiotics on a Litopenaeus vannamei biofloc culture system infected with Vibrio parahaemolyticus. Three replicates of two experimental treatments were conducted: a control system (without probiotic) and a system with the application of a multistrain probiotic containing Bacillus spp., Enterococcus spp., Thiobacillus spp., and Paracoccus spp. applied to the water and another multistrain probiotic containing Bacillus spp., Enterococcus spp., and Lactobacillus spp. added to the feed. Growth and survival rate were significantly higher in the probiotic treatment group (P < 0.05), and the shrimp in the probiotic group also had a lower (P < 0.05) FCR compared to the shrimp in the control group (1.4 vs. 2.7).  相似文献