Idiopathic arterial medial calcification of the thoracic arteries in an adult horse     

Amanda Fales-Williams  Beatrice Sponseller  Heather Flaherty 《Journal of veterinary diagnostic investigation》2008,20(5):692-697

A 6-year-old, gelded, Paint horse displayed clinical signs of muscle wasting and limb stiffness for a 6-month period. The horse's clinical signs abated with corticosteroid therapy, but returned upon cessation of treatment. Upon necropsy, severe lesions of aortic thickening and aortic valve rigidity were observed. Histologically, the tunica media of the aorta, coronary arteries, and pulmonary arteries were expanded by foci of elastin fiber calcification and extracellular matrix with lacunae formation. The vascular lesions are comparative to what has been described as medial arterial calcification, seen in humans suffering from chronic renal failure or diabetes mellitus. No exposure to vitamin D-containing plants or feedstuff could be documented at the time of onset or during the period of clinical signs. The current case describes dramatic lesions of arterial medial calcification of the aorta, coronary, and pulmonary arteries of undetermined cause.  相似文献   

Changes in thyroid and renal function after bilateral thyroidectomy in cats     

Heather L. Covey  Yu‐mei Chang  Jonathan Elliott  Harriet M. Syme 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2019,33(2):508-515

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Profitable and Sustainable Cattle Grazing Strategies Support Reptiles in Tropical Savanna Rangeland     

Heather Neilly  Peter O’Reagain  Jeremy Vanderwal  Lin Schwarzkopf 《Strength and Conditioning Journal》2018,71(2):205-212

Rangelands are areas used primarily for grazing by domestic livestock; however, because they support native vegetation and fauna, their potential role in conservation should not be overlooked. Typically, “off-reserve” conservation in agricultural landscapes assumes a trade-off between maintaining the ecological processes that support biodiversity and successful food production and profitability. To evaluate this potential biodiversity trade-off in rangelands, we need to understand the effect of different livestock grazing strategies on biodiversity, in relation to their performance in terms of profitability and land condition. We monitored reptile community responses to four cattle-grazing strategies (heavy, moderate, and variable stocking rates and a rotational wet season spelling treatment) in a replicated, long-term grazing trial in north Queensland, Australia. Simultaneously, measures of profitability and land condition were collected for the different grazing strategies. Overall, reptile abundance was not negatively impacted by the more sustainably managed treatments (moderate, variable, and rotational) compared with heavy stocking, although the effect of grazing treatment alone was not significant. Profitability and land condition were also higher in these treatments compared with the heavy stocking rate treatment. As drought conditions worsened over the 3 yr, the negative impact of the heavy stocking treatment on both profitability and biodiversity became more pronounced. Heavy stocking negatively impacted reptiles and was also the least profitable grazing strategy over the long term, resulting in the worst land condition. This suggests that in this tropical savanna rangeland there was no trade-off between economic performance and reptile abundance and diversity. Grazing regimes with a moderate stocking rate or flexible management strategies were better able to buffer the effects of climate variability. The consequence was a more resilient reptile community and better economic outcomes in dry years.  相似文献   

Pharmacokinetics and recovery effects of postanesthetic administration of xylazine and dexmedetomidine following isoflurane anesthesia in horses     

Caroline Baldo  Laura Tucker  Daniel Almeida  Erin Wendt-Hornickle  Sandra Allweiler  Heather Knych  Alonso Guedes 《Veterinary anaesthesia and analgesia》2018,45(6):885.e1-885.e2

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Leading the pack: Best practices in comparative canine cancer genomics to inform human oncology     

Cheryl A. London  Heather Gardner  Shaying Zhao  Deborah W. Knapp  Sagar M. Utturkar  Dawn L. Duval  Melissa R. Chambers  Elaine Ostrander  Jeffrey M. Trent  Gina Kuffel 《Veterinary and comparative oncology》2023,21(4):565-577

Pet dogs develop spontaneous cancers at a rate estimated to be five times higher than that of humans, providing a unique opportunity to study disease biology and evaluate novel therapeutic strategies in a model system that possesses an intact immune system and mirrors key aspects of human cancer biology. Despite decades of interest, effective utilization of pet dog cancers has been hindered by a limited repertoire of necessary cellular and molecular reagents for both in vitro and in vivo studies, as well as a dearth of information regarding the genomic landscape of these cancers. Recently, many of these critical gaps have been addressed through the generation of a highly annotated canine reference genome, the creation of several tools necessary for multi-omic analysis of canine tumours, and the development of a centralized repository for key genomic and associated clinical information from canine cancer patients, the Integrated Canine Data Commons. Together, these advances have catalysed multidisciplinary efforts designed to integrate the study of pet dog cancers more effectively into the translational continuum, with the ultimate goal of improving human outcomes. The current review summarizes this recent progress and provides a guide to resources and tools available for comparative study of pet dog cancers.  相似文献   

Bilateral corneal dermoids associated with bilateral choroido–scleral colobomas in a cat: retinographic and optical coherence tomography study with surgical outcome and follow–up     

Sophie Andree Cognard  Charles Cassagnes  Gilles Chaudieu  Heather Manning 《Veterinary ophthalmology》2023,26(4):367-373

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In vitro and in vivo germination of spores of Marssonina brunnea (Ell. et Ev.) P. Magn     

W. A. Heather  N. Anselmi  C. P. Cellerino 《Forest Pathology》1975,5(6):321-328

A water soluble inhibitor of germination is present on the surfaces of freshly collected spores of Marssonina brunnea (Ell et Ev.) P. Magn. Spores of this pathogen have a high potential for germination even in the absence of external substrates. Among the poplar clones examined there was no correlation between spore germination on leaf discs and the disease reaction of the discs under controlled conditions. However under these conditions the disease development on leaf discs taken from clone I-69/55 was correlated with the high resistance of this clone to Marssonina leaf spot in the field.  相似文献   

Temperature-light sensitivity of infection types expressed by cultivars of Populus deltoides Marsh. to races of Melampsora medusae Thüm.     

S. J. Singh  W. A. Heather 《Forest Pathology》1982,12(6):327-331

Infection types were assessed when four cultivars of Populus deltoides Marsh. were inoculated with six races of Melampsora medusae Thüm. and incubated in combinations of light intensity (100, 500 and 1000 μEm^-2s^-1) and temperature (15 and 25°C). Resistance in the cultivars was always at a maximum when the race/cultivar complexes were incubated in the light intensity (1000 μ^-2s^-1)/high temperature (25°C) regime. Inereasing light intensity was generally associated with reduced infection type in the cultivars; the reduction was more pronounced in an incubation temperature of 25 than 15°C. The potential epidemiological significance of the results is discussed.  相似文献   

Comparison of children's diets as reported by the child via the Youth/Adolescent Questionnaire and the parent via the Willett food-frequency questionnaire     

Lamb MM  Ross CA  Brady HL  Norris JM 《Public health nutrition》2007,10(7):663-670

OBJECTIVE: A comparison of a parent-completed Willett food-frequency questionnaire (FFQ) and a self-completed Youth/Adolescent Questionnaire (YAQ) has not yet been conducted. SETTING: In the Diabetes Autoimmunity Study in the Young (DAISY), parents report their child's diet on the FFQ annually from birth until age 10 years, when the child begins to report their own diet using the YAQ. SUBJECTS: To determine the comparability of these collection methods, 89 children aged 10-17 years and their parents completed the YAQ and FFQ, respectively, for the child's previous year's diet. DESIGN: We compared reported intakes for energy, the macronutrients and a variety of micronutrients of interest to the DAISY study. RESULTS: Bland-Altman plots of energy-adjusted differences between questionnaire responses against their means suggested that the two collection methods gave similar results. The average Spearman correlation coefficient of all energy-adjusted nutrient intakes was 0.50, and did not differ significantly by gender (males, r=0.48; females, r=0.46) or age (10-11 years, r=0.49; 12-17 years, r=0.51). While correlated, the nutrient values from the FFQ were higher than the nutrient values from the YAQ. CONCLUSIONS: While reported nutrient intakes are correlated, an indicator variable defining which survey method a nutrient was collected with should be included in any longitudinal data analyses examining nutrient intakes collected with the YAQ and the FFQ as independent predictors of a disease outcome.  相似文献   

Adiposity, education and weight loss effort are independently associated with energy reporting quality in the Ontario Food Survey     

Ward H  Tarasuk V  Mendelson R 《Public health nutrition》2007,10(8):803-809

OBJECTIVES: To examine the associations of adiposity, dietary restraint and other personal characteristics with energy reporting quality. DESIGN/SUBJECTS: Secondary analysis of 230 women and 158 men from the 1997/98 Ontario Food Survey. METHODS: Energy reporting quality was estimated by ratios of energy intake (EI) to both basal metabolic rate (BMR) and total energy expenditure (TEE). Multivariate regression analyses were conducted to examine energy reporting quality between two dietary recalls and in relation to body mass index (BMI) with adjustment for potential confounders. Energy reporting quality was explored across categories of age, BMI, income, education, dieting status and food insecurity through analysis of variance (ANOVA). RESULTS: From the ANOVA, energy reporting quality was associated with BMI group, age category and weight loss for men and women, as well as with education among women (P 0.05). EI:BMR and EI:TEE on the first and second 24-hour recalls were positively related (P < 0.0001 for men and women). A higher proportion of variance in energy reporting quality was explained for women than for men (R2 = 0.19 and 0.14, respectively). CONCLUSIONS: Studies of diet and adiposity are probably hindered to some extent by BMI-related variation in energy reporting quality. Methods to address this issue are urgently needed if population surveys will continue to serve as the primary source of dietary intake data.  相似文献