Bioequivalence of a new liquid formulation of benazepril compared with the reference tablet product     

K Kelers  JL Devi  GA Anderson  P Zahra  JH Vine  T Whittem 《Australian veterinary journal》2013,91(8):312-319

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Epistaxis in racehorses: risk factors and effects on career     

JL Langford  PC Thomson  PK Knight 《Australian veterinary journal》2013,91(5):198-203

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Bioavailability of two L‐thyroxine formulations after oral administration to healthy dogs     

C Simpson  JL Devi  T Whittem 《Australian veterinary journal》2013,91(3):83-88

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Porcine parvovirus infection in a commercial piggery     

D.J. Hampson  K. Moller  I.D. Robertson  Z.F. Fu 《New Zealand veterinary journal》2013,61(5)

Abstract

Extract

Madam:– We have recently been involved in a consultative role with a 60-sow commercial piggery. Over the year preceding the incident recorded here, this unit had approximately doubled in size by the purchase of improved large white gilts. An infertility problem involving irregular returns to service and small litter sizes was first noted around Christmas 1984. In early January 1985 all the adult stock were bled and serological tests undertaken. There was no evidence of infection with Aujeszky's disease virus or leptospires, but 42 sows had haemagglutination inhibition (HI) titres(2 Joo, H.O., Donaldson-Wood, C. and Johnson, R.H. 1976. A standardised haemagglutination inhibition test for porcine parvovirus antibody. Aust. vet. J., 52: 422–424.  [Google Scholar]) of >320 against porcine parvovirus (PP), and were considered to have been actively infected. (1 Johnston, R.H., Donaldson-Wood, C., Joo, H.O. and Allender, U. 1976. Observations on the epidemiology of porcine parvovirus. Aust. vet. J., 52: 80–84.  [Google Scholar]) Seventeen other gilts and sows in their second pregnancy had titres ?320 and were considered to be still susceptible to infection. These animals were bled again 75 days later and HI tests on the paired sera showed that 15 of the 17 had now scroconverted (minimum titre 1,280). Eleven of these animals were in early to mid-pregnancy during the period of seroconversion. Five of these animals subsequently failed to farrow, and the remaining six produced a mean of only 6.5 (S.D. 2.8) live piglets at birth. In contrast the two animals which did not seroconvert, and four other previously infected gilts with HI titre of >10,240 at the first bleeding, produced a mean of 9.8 (S.D. 1.7) live piglets. This was considered a satisfactory live birth rate for this age group, and was significantly higher (Student's t-test; P<0.05) than for the six sows which seroconverted and produced live pigs.  相似文献   

Peroxidase-mediated oxidative cross-linking and its potential to modify mechanical properties in water-soluble polysaccharide extracts and cereal grain residues     

Robertson JA  Faulds CB  Smith AC  Waldron KW 《Journal of agricultural and food chemistry》2008,56(5):1720-1726

Analysis of wheat bran and spent grain shows that concentrations of ferulate and diferulates offer considerable scope to modify the cross-linking of feruloylated polysaccharides and hence the mechanical properties of these residues. In solution ferulic acid (FA) can be readily polymerized by horseradish peroxidase, but when esterified to a polysaccharide, the profile of diferulates becomes restricted. This situation also exists in muro and suggests structural constraints may limit the availability of FA for cross-linking. At relatively low polysaccharide concentration, (approximately 3%), steric restrictions were apparent in gels prepared using isolated polysaccharides. Mechanical properties such as swelling also appear to be fixed at these relatively low polysaccharide concentrations. This limits the potential to modify mechanical properties in muro through oxidoreductase activity. To modify mechanical properties such treatments will need to focus on increasing the "flexibility" of the cell wall matrix and the accessibility of enzymes to the cell wall matrix.  相似文献   

Influence of climate and abundance on migration timing of adult Atlantic salmon (Salmo salar) among rivers in Newfoundland and Labrador          下载免费PDF全文

Brian Dempson  Carl J. Schwarz  Ian R. Bradbury  Martha J. Robertson  Geoffrey Veinott  Rebecca Poole  Eugene Colbourne 《Ecology of Freshwater Fish》2017,26(2):247-259

Evidence mounts for the influence of climate variability on temporal trends in the phenology of many organisms including various species of fish. Accordingly, we examined variation in adult Atlantic salmon Salmo salar run timing in thirteen Newfoundland and Labrador rivers where returns were monitored at fishways or fish‐counting fences. Run timing varied significantly among rivers with the median date of return differing by up to 5 weeks. Duration of runs was generally short with most adults returning over a period of three to 5 weeks. A mixed model analysis incorporating a first‐order autoregressive error structure was used to generalise changes in run timing among all monitored rivers. Results indicated that the median date of return has advanced by almost 12 days over a 35‐year interval from 1978 to 2012, while several individual rivers have advanced by almost 21 days. The influence of climate on median timing was evident when the simultaneous effects of both climate and salmon abundance were controlled. We found earlier runs associated with overall warmer climate conditions on the Newfoundland and Labrador Shelf. Results contrast with those from the north‐east Atlantic where Atlantic salmon are returning later in some rivers coincident with warming climate conditions.  相似文献   

Rural veterinary services in Western Australia: Part B. Rural practice   总被引：1，自引：1，他引：0  

Maxwell JA  Costa ND  Layman LL  Robertson ID 《Australian veterinary journal》2008,86(3):74-80

OBJECTIVE: To determine the current status of rural veterinary services in Western Australia. PROCEDURE: A questionnaire was sent to all eligible rural practitioners registered in 2006 and the replies were transferred to Microsoft Excel for analysis. RESULTS: Of the rural practitioners invited to participate in the survey replies were received from 67%. There were equal numbers of females and males. Their mean age was 44 years. Ninety per cent of respondents considered knowledge gained as an undergraduate was sufficient to equip them for practice, but only 60% considered their practical skills adequate. Thirteen per cent of those in rural practices in 2005 had left by 2006. Eighty-nine per cent of respondents were in mixed practice, the balance in specific species practice, such as equine, large animal and production animal consultancy. The majority of rural practitioners relied on servicing companion animals for their viability; 7% earned their income from servicing production animals only. Seventy per cent utilised merchandising and the sale of pet foods to supplement the income received from the traditional veterinary services and 34% found it necessary to earn an independent income. A quarter considered that rural practice did not have a future. CONCLUSION: The majority of rural practitioners in Western Australia depend on companion animals, not production animals, to remain viable, with very few operating production animal services. Poor remuneration is a major reason why veterinarians leave rural practice, and many find it necessary to supplement their income or develop an independent income.  相似文献   

An Association Analysis Between a Silent C558T Polymorphism at the Pig Vascular Cell Adhesion Molecule 1 Locus and Sow Reproduction and Piglet Survivability Traits     

O Ramirez  A Tomàs  J Casellas  M Blanch  JL Noguera  M Amills 《Reproduction in domestic animals》2008,43(5):542-546

The vascular cell adhesion molecule 1 (VCAM1) has a strong influence on embryonic development and on the formation of the umbilical cord and placenta. These developmental processes are crucial to ensure the success of pregnancy. In this work, we have identified two T306A and C558T single nucleotide polymorphisms (SNP) at exons 2 and 3 of the pig VCAM1 locus, respectively. The T306A substitution involves a non conservative Asn to Lys replacement at amino acid position 102, whereas the C558T polymorphism is synonymous. An in silico prediction of the consequences of the Asn₁₀₂→Lys₁₀₂ mutation with the PolyPhen software revealed that it is not deleterious. The T306A SNP segregated in the Iberian, Piétrain, Duroc, Large White and Landrace breeds as well as in European wild boars. The C558T SNP also segregated and most of commercial standard breeds. The genotyping of the C558T SNP in an Iberian × Meishan intercross allowed to find a suggestive association (Bonferroni threshold, p < 0.004) between C558T genotype and time the newborn piglet needs to reach the udder (p = 0.013) as well as a significant one with time to make the first ingestion of colostrum (p = 0.003). The biological basis of these associations remains unclear and they should be interpreted with caution.  相似文献   

A novel herpesvirus associated with chronic superficial keratitis and proliferative conjunctivitis in a great horned owl (Bubo virginianus)     

Molly D. Gleeson  Bret A. Moore  Sydney G. Edwards  Sarah Stevens  April L. Childress  James F.X. Wellehan  Jessica Robertson  Christopher J. Murphy  Michelle G. Hawkins  Joanne Paul‐Murphy 《Veterinary ophthalmology》2019,22(1):67-75

An adult great‐horned owl (Bubo virginianus; GHOW) presented with a history of recurrent corneal ulceration of the right eye (OD). Findings included ulcerative superficial keratitis, proliferative conjunctivitis, and iris pigmentary changes. The ulcer was initially nonresponsive to medical therapy, but showed rapid and appropriate healing following diamond burr debridement. Proliferative conjunctivitis markedly improved following topical antiviral therapy with cidofovir 1%, interferon alpha 2B ophthalmic solutions, and oral l ‐lysine. Histopathologic evaluation of a conjunctival biopsy revealed epithelial features suspicious for viral cytopathic changes and intranuclear structures suspicious for viral inclusions, suggestive of a possible viral‐induced papillomatous conjunctivitis. A novel alphaherpesvirus, referred to as Strigid Herpesvirus 1 (StrHV1), was identified using PCR and gene sequencing. This case represents a new clinical manifestation of a previously unreported herpesvirus in the GHOW. Identification of the herpes virus was critical to administration of appropriate therapy and resolution of the conjunctivitis, and corneal epithelial debridement promoted resolution of the chronic corneal epithelial defect.  相似文献   

A review of feral cat control     

Robertson SA 《Journal of Feline Medicine and Surgery》2008,10(4):366-375

Animal overpopulation including feral cats is an important global problem. There are many stakeholders involved in the feral cat debate over 'what to do about the problem', including those who consider them a nuisance, the public at risk from zoonotic disease, people who are concerned about the welfare of feral cats, those concerned with wildlife impacts, and the cats themselves. How best to control this population is controversial and has ranged from culling, relocation, and more recently 'trap neuter return' (TNR) methods. Data support the success of TNR in reducing cat populations, but to have a large impact it will have to be adopted on a far greater scale than it is currently practised. Non-surgical contraception is a realistic future goal. Because the feral cat problem was created by humans, concerted educational efforts on responsible pet ownership and the intrinsic value of animals is an integral part of a solution.  相似文献