Degradation Kinetics of an Aged Hydrocarbon-Contaminated Soil   总被引：1，自引：0，他引：1  

Snežana Maletić  Božo Dalmacija  Srđan Rončević  Jasmina Agbaba  Olgica Petrović 《Water, air, and soil pollution》2009,201(1-4):149-159

PM2.5 and PM10 samples were collected in the urban atmosphere of Elche (southeastern Spain) between December 2004 and November 2005. The samples were analyzed for mass and water-soluble inorganic ions (Na⁺, ${\text{NH}}^{{\text{ + }}}_{{\text{4}}}$ , K⁺, Ca²⁺, Mg²⁺, Cl^?, ${\text{NO}}^{{\text{ - }}}_{{\text{3}}}$ and ${\text{SO}}^{{{\text{2 - }}}}_{{\text{4}}}$ ) with the aim of investigating the influence of the climatic and geographic features of a coastal semiarid area on the contribution of these species to PM levels. Secondary inorganic ions ( ${\text{SO}}^{{{\text{2 - }}}}_{{\text{4}}}$ , ${\text{NO}}^{{\text{ - }}}_{{\text{3}}}$ , ${\text{NH}}^{{\text{ + }}}_{{\text{4}}}$ ) were the major components in the fine fraction (PM2.5), accounting for 40% of the total mass. The relationship between non-marine ${\text{SO}}^{{{\text{2 - }}}}_{{\text{4}}}$ and ${\text{NH}}^{{\text{ + }}}_{{\text{4}}}$ indicated that fine sulfate particles were completely neutralized by ammonium. In the coarse fraction (PM10–2.5), nitrate (as NaNO₃ and Ca(NO₃)₂), together with crustal (CaCO₃) and marine species (NaCl) accounted for almost 50% of the total mass. Fine sulfate and coarse nitrate showed summer maximums. In contrast, the concentrations of fine ${\text{NO}}^{{\text{ - }}}_{{\text{3}}}$ were lowest in the warm period. Ammonium presented both winter and summer maximums. The levels of marine ions, except for coarse Cl^?, were highest in summer when the dominant wind flow is from the sea. No significant seasonal variations were observed for coarse Ca²⁺ and ${\text{SO}}^{{{\text{2 - }}}}_{{\text{4}}}$ . The concentrations of all inorganic ions increased during Saharan dust events, in particular, fine ${\text{NH}}^{{\text{ + }}}_{{\text{4}}}$ and ${\text{SO}}^{{{\text{2 - }}}}_{{\text{4}}}$ and coarse $NO_3^ - $ . Coarse calcium was proved not to be a good tracer for this type of episode in our region since the average levels of this cation are elevated and the relative increase in its concentrations during African events was not as high as expected.  相似文献   

Rat bite fever     

Wim Gaastra  Ron Boot  Hoa T.K. Ho  Len J.A. Lipman 《Veterinary microbiology》2009

Rat bite fever (RBF) is a bacterial zoonosis for which two causal bacterial species have been identified: Streptobacillis moniliformis and Spirillum minus. Haverhill fever (HF) is a form of S. moniliformis infection believed to develop after ingestion of contaminated food or water.  相似文献   

Clinical evaluation of pimecrolimus eye drops for treatment of canine keratoconjunctivitis sicca: a comparison with cyclosporine A     

Ofri R  Lambrou GN  Allgoewer I  Graenitz U  Pena TM  Spiess BM  Latour E 《Veterinary journal (London, England : 1997)》2009,179(1):70-77

The aim of this study was to evaluate the efficacy of pimecrolimus oil-based eye drops in alleviating the clinical signs of keratoconjunctivitis sicca (KCS) in dogs and to compare the efficacy with that of cyclosporine A (CsA) ointment. An open-label, multicenter study enrolling 44 dogs previously untreated with CsA was conducted. Dogs were randomly assigned to a treatment group and medicated twice daily for 8 weeks. After that time the mean increase (+/-SEM) in the Schirmer tear test was 9.2+/-1.6 mm/min in the pimecrolimus group and 5.8+/-1.1 mm/min in the CsA group (P=0.085). The improvement in clinical signs of inflammation in eyes treated with pimecrolimus was significantly greater than in eyes treated with CsA (P=0.02). The results show that 1% pimecrolimus oily eye drops are as safe as and more effective than CsA ointment in controlling KCS in dogs.  相似文献   

Vigor-controlling rootstocks affect early shoot growth and leaf area development of kiwifruit     

Clearwater MJ  Seleznyova AN  Thorp TG  Blattmann P  Barnett AM  Lowe RG  Austin PT 《Tree physiology》2006,26(4):505-515

Patterns of shoot development and the production of different types of shoots were compared with scion leaf area index (LAI) to identify how eight clonal Actinidia rootstocks influence scion development. Rootstocks selected from seven Actinidia species (A. chrysantha Merri., A. deliciosa (A. Chev.) C. F. Liang et A.R. Ferguson, A. eriantha Benth., A. hemsleyana Dunn, A. kolomikta (Maxim. et Rupr.) Maxim., A. kolomikta C.F. Liang and A. polygama (Sieb. et Zucc.) Maxim.) were grafted with the scion Actinidia chinensis Planch. var. chinensis 'Hort16A' (yellow kiwifruit). Based on an earlier architectural analysis of A. chinensis, axillary shoot types produced by the scion were classified as short, medium or long. Short and medium shoots produced a restricted number of preformed leaves before the shoot apex ceased growth and aborted, resulting in a 'terminated' shoot. The apex of long shoots continued growth and produced more nodes throughout the growing seasons. Mid-season LAI of the scion was related to the proportion of shoots that ceased growth early in the season. Scions on low-vigor rootstocks had 50% or less leaf area than scions on the most vigorous rootstocks and had a higher proportion of short and medium shoots. On low-vigor rootstocks, a higher proportion of short shoots was retained during pruning to form the parent structure of the following year. Short parent shoots produced a higher proportion of short daughter shoots than long parent shoots, thus reinforcing the effect of the low-vigor rootstocks. However, overall effects of rootstock on shoot development were consistent regardless of parent shoot type and nodal position within the parent shoot. Slower-growing shoots were more likely to terminate and scions on low-vigor rootstocks produced a higher proportion of slow-growing shoots. Shoot termination also occurred earlier on low-vigor rootstocks. The slower growth of terminating shoots was detectable from about 20 days after bud burst. Removal of a proportion of shoots at the end of bud burst increased the growth rate and decreased the frequency of termination of the remaining shoots on all rootstocks, indicating that the fate of a shoot was linked to competitive interactions among shoots during initial growth immediately after bud burst. Rootstock influenced the process of shoot termination independently of its effect on final leaf size. Scions on low-vigor rootstocks had a higher proportion of short shoots and short shoots on all rootstocks had smaller final leaf sizes at equivalent nodes than medium or long shoots. Only later in the development of long shoots was final leaf size directly related to rootstock, with smaller leaves on low-vigor rootstocks. Thus, the most important effect of these Actinidia rootstocks on scion development occurred during the initial period of shoot growth immediately after bud burst.  相似文献   

Atomic-level characterization of the structural dynamics of proteins   总被引：1，自引：0，他引：1  

Shaw DE  Maragakis P  Lindorff-Larsen K  Piana S  Dror RO  Eastwood MP  Bank JA  Jumper JM  Salmon JK  Shan Y  Wriggers W 《Science (New York, N.Y.)》2010,330(6002):341-346

Molecular dynamics (MD) simulations are widely used to study protein motions at an atomic level of detail, but they have been limited to time scales shorter than those of many biologically critical conformational changes. We examined two fundamental processes in protein dynamics--protein folding and conformational change within the folded state--by means of extremely long all-atom MD simulations conducted on a special-purpose machine. Equilibrium simulations of a WW protein domain captured multiple folding and unfolding events that consistently follow a well-defined folding pathway; separate simulations of the protein's constituent substructures shed light on possible determinants of this pathway. A 1-millisecond simulation of the folded protein BPTI reveals a small number of structurally distinct conformational states whose reversible interconversion is slower than local relaxations within those states by a factor of more than 1000.  相似文献   

In vitro erythrocytic membrane effects of dibenzyl trisulfide, a secondary metabolite of Petiveria alliacea     

D.J. Pepple  A.A. Richards  D.A. Lowe  W.A. Reid  N.O. Younger  L.A.D. Williams 《Fitoterapia》2010,81(8):1113-1116

We investigated the in vitro effect of dibenzyl trisulfide (DTS), a secondary metabolite of Petiveria alliacea, on erythrocyte elasticity, relaxation time and membrane morphology. Blood samples from 8 volunteers with hemoglobin AA were exposed to 100, 200, 400, 800 and 1000 ng/ml of DTS respectively and the elasticity and relaxation time measured. There were statistically significant, dose-dependent increases in elasticity and relaxation times. The changes in membrane morphology observed also increased with increased concentration of DTS. This suggests that DTS interaction with membrane protein resulted in increased elasticity, relaxation time and deformation of the erythrocyte membrane.  相似文献   

Protection by polyphenols of postprandial human plasma and low-density lipoprotein modification: the stomach as a bioreactor     

Kanner J  Gorelik S  Roman S  Kohen R 《Journal of agricultural and food chemistry》2012,60(36):8790-8796

Recent studies dramatically showed that the removal of circulating modified low-density lipoprotein (LDL) results in complete prevention of atherosclerosis. The gastrointestinal tract is constantly exposed to food, some of it containing oxidized compounds. Lipid oxidation in the stomach was demonstrated by ingesting heated red meat in rats. Red wine polyphenols added to the rats' meat diet prevented lipid peroxidation in the stomach and absorption of malondialdehyde (MDA) in rat plasma. In humans, postprandial plasma MDA levels rose by 3-fold after a meal of red meat cutlets. MDA derived from meat consumption caused postprandial plasma LDL modification in human. The levels of plasma MDA showed a 75% reduction by consumption of red wine polyphenols during the meat meal. Locating the main biological site of action of polyphenols in the stomach led to a revision in the understanding of how antioxidants work in vivo and may help to elucidate the mechanism involved in the protective effects of polyphenols in human health.  相似文献   

Occurrence of pharmaceutical and personal care products (PPCPs) in marine sediments in the Todos os Santos Bay and the north coast of Salvador,Bahia, Brazil     

Magda Beretta  Vicky Britto  Tania Mascarenhas Tavares  Sonilda Maria Teixeira da Silva  Adelmo Lowe Pletsch 《Journal of Soils and Sediments》2014,14(7):1278-1286

Purpose

The Todos os Santos Bay is the largest bay in Brazil and receives drainage from various watersheds. For more than 450 years, it was the main destination for the domestic and hospital sewage from the city of Salvador, Bahia. With the growing concern regarding the presence of pharmaceutical and personal care products (PPCPs) in the environment, an investigation was undertaken to determine the presence and levels of some commonly used drugs (i.e., atenolol, caffeine, carbamazepine, diazepam, diclofenac, erythromycin, ibuprofen) and personal care products (i.e., galaxolide, tonalide), using sediments as an indicator of their presence in the water column.

Material and methods

Surficial sediment samples from 17 stations located in the intertidal zone of the Todos os Santos Bay and infralittoral zone along the north coast of Salvador were tested for the presence of some PPCPs using LC-MS/MS (for drugs) and GC-MS/MS (for fragrances).

Results and discussion

The PPCPs examined were present in all sediment samples at levels of parts per billion of dry sediment. The highest concentrations were found for the fragrances galaxolide (52.5 ng g^?1) and tonalide (27.9 ng g^?1), followed by caffeine (23.4 ng g^?1) and pharmaceuticals ibuprofen (14.3 ng g^?1), atenolol (9.84 ng g^?1), carbamazepine (4.81 ng g^?1), erythromycin (2.29 ng g^?1), diclofenac (1.06 ng g^?1), and diazepam (0.71 ng g^?1).

Conclusions

Pharmaceuticals were found to be ubiquitous in the sediments of the study areas. The texture of the sediment was an important factor in PPCPs fixation and deposition. The concentrations of all PPCPs had statistically significant positive correlations with the percentage of clay in the sediments.  相似文献   

Neoliberal reform and the veterinary profession     

Enticott G  Lowe P  Wilkinson K 《The Veterinary record》2011,169(13):327-329

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Post-mortem examination and laboratory-based analysis for the diagnosis of bovine tuberculosis among dairy cattle in Ecuador     

Proaño-Pérez F  Benitez-Ortiz W  Desmecht D  Coral M  Ortiz J  Ron L  Portaels F  Rigouts L  Linden A 《Preventive veterinary medicine》2011,101(1-2):65-72

Veterinary inspection in slaughterhouses allows for the detection of macroscopic lesions reminiscent of bovine tuberculosis, but the presence of Mycobacterium bovis must be confirmed by laboratory methods. This study aimed at comparing the performances of the standard diagnostic tools used to identify M. bovis in tissue specimens sampled from suspicious animals. During a two years period, 1390 cattle were inspected at the Machachi abattoir in the Mejia canton - Ecuador. A total of 33 animals with granulomatous lesions were detected, representing 2.33% (16/687) and 2.42% (17/703) animals examined in 2007 and 2008, respectively. Ninety-four tissue specimens were sampled and screened for the presence of mycobacteria. Acid-fast bacilli were identified in one third of the suspicious cattle (11/33) and suggestive microscopic lesions in 27.3% (9/33) of the samples examined by direct microscopy and histopathology, respectively. Culturing on Stonebrink medium and 16S-rRNA-based polymerase chain reaction (PCR) yielded 36.4% (12/33) and 27.3% (9/33) of positives, respectively. Compared to culture, other diagnostic procedures displayed a lower sensitivity, with 56.5% for PCR, and 43.5% for direct microscopy and histopathology; however, the specificity was higher (94.4% for PCR and microscopy, and 97.2% for histopathology). We conclude that reliable post-mortem laboratory testing either requires the combination of a set of available diagnostic tools or necessitates the development of improved new-generation tools with better sensitivity and specificity characteristics.  相似文献