Carcinogen in rock fern (Cheilanthes sieberi) from New Zealand and Australia     

BL SMITH  PP EMBLING  DR LAUREN  MP AGNEW  AD ROSS  PL GREENTREE 《Australian veterinary journal》1989,66(5):154-155

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Bluetongue and Douglas virus activity in New South Wales in 1989: further evidence for long-distance dispersal of the biting midge Culicoides brevitarsis     

MP WARD 《Australian veterinary journal》1995,72(5):197-197

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Unexpected death in a horse with arytenoid chondritis and perilaryngeal lesions     

MP FRANCE  TLW ROTHWELL  NJ KANNEGIETER† 《Australian veterinary journal》1995,72(9):351-352

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Luteal Characteristics and Progesterone Production on Day 5 of the Bovine Oestrous Cycle     

MP Green  GE Mann  MG Hunter 《Reproduction in domestic animals》2007,42(6):643-647

In this study we have examined luteal function in non-lactating and late lactation dairy cows on day 5 of the cycle, during the period of the post-ovulatory progesterone rise. Comparison of luteal progesterone content and in vitro synthetic capacity with circulating plasma progesterone demonstrated that circulating progesterone concentration is a function of total luteal activity rather than the activity of individual units of tissue. Incubation of luteal tissue in vitro demonstrated stimulatory activity of LH and IGF-I, and to a greater degree IGF-II, on luteal progesterone synthesis. Finally the study showed no effect of double ovulation on luteal function. Occurrence of double ovulation in 35% of animals was not associated with any difference in luteal function or plasma progesterone concentrations.  相似文献   

Euglena gracilis: a novel lipid energy reserve and arachidonic acid enrichment during fasting   总被引：1，自引：0，他引：1  

A Rosenberg 《Science (New York, N.Y.)》1967,157(793):1189-1191

In Euglena gracilis grown in the dark, was esters, consisting of a combination of medium-chain fatty acids and alcohols that contain both odd and even numbers of carbon atoms, appear to be a reservoir for metabolic energy. When the organisms are fasted, their pellicular membrane systems become quite rich in long-chain polyenoic acids, mostly of the arachidonic acid family.  相似文献   

Space applications: Earth-oriented applications of unmanned satellites     

Rosenberg P 《Science (New York, N.Y.)》1968,162(3856):939-940

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Meta-analysis in plant pathology: synthesizing research results     

Rosenberg MS  Garrett KA  Su Z  Bowden RL 《Phytopathology》2004,94(9):1013-1017

ABSTRACT Meta-analysis is a set of statistical procedures for synthesizing research results from a number of different studies. An estimate of a statistical effect, such as the difference in disease severity for plants with or without a management treatment, is collected from each study along with a measure of the variance of the estimate of the effect. Combining results from different studies will generally result in increased statistical power so that it is easier to detect small effects. Combining results from different studies may also make it possible to compare the size of the effect as a function of other predictor variables such as geographic region or pathogen species. We present a review of the basic methodology for meta-analysis. We also present an example of meta-analysis of the relationship between disease severity and yield loss for foliar wheat diseases, based on data collected from a decade of fungicide and nematicide test results.  相似文献   

Bovine viral diarrhoea virus (‘pestivirus’) in Australia: to control or not to control?     

SR Lanyon  MP Reichel 《Australian veterinary journal》2014,92(8):277-282

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Calcium channels in planar lipid bilayers: insights into mechanisms of ion permeation and gating   总被引：13，自引：0，他引：13  

R L Rosenberg  P Hess  J P Reeves  H Smilowitz  R W Tsien 《Science (New York, N.Y.)》1986,231(4745):1564-1566

Electrophysiological recordings were used to analyze single calcium channels in planar lipid bilayers after membranes from bovine cardiac sarcolemmal vesicles had been incorporated into the bilayer. In these cell-free conditions, channels in the bilayer showed unitary barium or calcium conductances, gating kinetics, and pharmacological responses that were similar to dihydropyridine-sensitive calcium channels in intact cells. The open channel current varied in a nonlinear manner with voltage under asymmetric (that is, physiological) ionic conditions. However, with identical solutions on both sides of the bilayer, the current-voltage relation was linear. In matched experiments, calcium channels from skeletal muscle T-tubules differed significantly from cardiac calcium channels in their conductance properties and gating kinetics.  相似文献   

A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis     

Winn MP  Conlon PJ  Lynn KL  Farrington MK  Creazzo T  Hawkins AF  Daskalakis N  Kwan SY  Ebersviller S  Burchette JL  Pericak-Vance MA  Howell DN  Vance JM  Rosenberg PB 《Science (New York, N.Y.)》2005,308(5729):1801-1804

Focal and segmental glomerulosclerosis (FSGS) is a kidney disorder of unknown etiology, and up to 20% of patients on dialysis have been diagnosed with it. Here we show that a large family with hereditary FSGS carries a missense mutation in the TRPC6 gene on chromosome 11q, encoding the ion-channel protein transient receptor potential cation channel 6 (TRPC6). The proline-to-glutamine substitution at position 112, which occurs in a highly conserved region of the protein, enhances TRPC6-mediated calcium signals in response to agonists such as angiotensin II and appears to alter the intracellular distribution of TRPC6 protein. Previous work has emphasized the importance of cytoskeletal and structural proteins in proteinuric kidney diseases. Our findings suggest an alternative mechanism for the pathogenesis of glomerular disease.  相似文献