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971.
972.
The ultrastructural appearance at primary and metastatic sites of ten ovine small intestinal adenocarcinomas was that of scirrhous tubular adenocarcinoma. Polygonal undifferentiated tumor cells had desmosomes, folded nuclei, and moderate numbers of mitochondria but few other organelles. More differentiated cells were columnar with apical microvilli and basal nuclei. They contained granular endoplasmic reticulum, Golgi and secretory granules. Microvillus-lined intracytoplasmic lumina (5-10 micron diameter), fibrous filaments (10 nm diameter, up to 1.4 micron length) and tubular paracrystalline arrays (hexagonal symmetry, 37-nm periodicity) in lumina and secretory granules were seen in some tumor cells in all ten sheep.  相似文献   
973.
Effects of xylazine HCl (0.5 mg/kg of body weight, IV) and/or butorphanol tartrate (0.04 mg/kg, IV) or neostigmine methylsulfate (0.022 mg/kg, IV) on myoelectric activity of the cecum and right ventral colon were studied in 4 conscious female ponies. Eight bipolar Ag/AgCl electrodes were sequentially placed on the seromuscular layer of the cecum (6 electrodes) and right ventral colon (2 electrodes). Recordings began 30 minutes before and continued for 90 minutes after drug administration. Each drug or drug combination was studied on 2 occasions in each pony. Two major patterns of coordinated spike bursts were identified. A series of coordinated spike bursts began at the cecal base and was conducted to the cecal apex (pattern I). A series of coordinated spike bursts began at the cecal apex, traversed the cecum, cecocolic orifice, and right ventral colon and was termed a progressive pattern (pattern II). Xylazine administration caused a significant decrease in patterns I and II for 20 minutes (P less than 0.05). Butorphanol tartrate administration caused a significant decrease in the progressive pattern for 10 minutes (P less than 0.05) without affecting the orally directed pattern. Administration of the combination of xylazine/butorphanol significantly decreased the frequency of pattern I for 40 minutes (P less than 0.05) and pattern II for 30 minutes (P less than 0.05). Neostigmine administration caused a significant increase in the frequency of pattern II for 30 minutes (P less than 0.05) without affecting pattern I (P greater than 0.05). Changes in conduction velocity of pattern I or II or the duration of spiking activity were not significantly different because of any treatment.  相似文献   
974.
Surgical diseases of the equine cecum   总被引:1,自引:0,他引:1  
Cecal impaction and cecal perforation, the two most common equine cecal diseases, are thought to develop after slowing or interruption of a single progressive motility pattern, which begins in a pacemaker area near the apex, occurs once every 3 minutes, and propels ingesta from the cecum to the right ventral colon. Rectal examination in horses with cecal impaction is the most useful technique to grade the severity of the condition. Medical treatment is undertaken if the impaction is judged to be mild to moderate. Surgical correction of cecal impaction in severe cases requires a ventral midline celiotomy, and exploration reveals a large ingesta-filled cecum and relatively empty large colon. Currently, the techniques of typhlotomy with manual evacuation of ingesta, combined with a complete bypass of the cecum by use of a jejunocolostomy, is the preferred method of surgical management. The use of a cecocolic anastomosis remains a viable alternative surgical procedure. Cecal perforation (CP), a uniformly fatal disease of horses, most often develops when the subtle signs of cecal impaction are missed or are masked by the administration of nonsteroidal antiinflammatory agents. CP can occur in mares around the time of foaling and, in this form, is not associated with cecal outflow dysfunction. Surgical management of cecocecal or cecocolic intussusception is required and involves resection of the diseased portion of cecum, either with extra- or intraluminal techniques. Both the side-to-side and end-to-side jejunocecal anastomoses are useful and successful techniques for bypass of simple or strangulating lesions of the ileum.  相似文献   
975.
976.
The present study was undertaken to characterize and estimate cat mortality caused by motor vehicles in Baltimore, Md. Analysis of Municipal Animal Shelter records revealed that the number of dead cats annually removed from Baltimore streets averaged 2,721 over 3 years. The number of cats removed per year was notably constant (range 2,621 to 2,917), with a consistently greater number of animals being picked up during summer months. A map of the location of 634 dead cats removed from city streets showed that areas of highest cat mortality were associated with areas of highest human population density. This map was used to stratify Baltimore into areas of high, medium, and low cat mortality for subsequent stratified random placement of tagged dead cats for the mark-recapture study. One hundred fifteen tagged dead cats were placed on city streets during the course of 1 year, and 50.5% were retrieved by the Municipal Animal Shelter. We estimate over 5,000 free-ranging cats are killed by automobiles/year in Baltimore. Analysis of 212 dead cats removed from city streets showed that the majority were male (63%) and that most animals were sexually intact (90%). At least 20% of the dead animals was previously owned, and few kittens or juvenile cats were found in the sample.  相似文献   
977.
Normal motility of the cecum and right ventral colon in ponies   总被引:1,自引:0,他引:1  
To study the normal motility of the cecum and right ventral colon (RVC) in 3 mature Shetland ponies, a 6-part, indwelling, intraluminal catheter system was used to measure intraluminal pressure changes. Three catheters were placed in the cecum at 10, 25, and 40 cm from the cecocolic orifice, and 3 catheters were placed in the RVC at 10, 20, and 30 cm from the cecocolic orifice. Recordings were made during the interdigestive period beginning 2 weeks after surgical operation was done. Frequent, low-amplitude peaks (0.35 +/- 0.13 coordinated peaks/min) were seen involving the cecal body and caudal cecal base, which represented a haustra-to-haustra mixing pattern. Coordinated pressure peaks originated in the cecal body and progressed to the cranial cecal base (0.07 +/- 0.01/min) or originated in the cranial cecal base and progressed to the cecal body (0.07 +/- 0.04/min). Associated with a loud rush of ingesta heard on transabdominal auscultation and progression of liquid ingesta confirmed with barium contrast radiography, there was a series of coordinated, progressive pressure peaks which originated in the cecal body, sequentially involved the cecal base, traversed the cecocolic orifice, and extended into the RVC (0.36 +/- 0.05/min). It seemed that a pacemaker region existed in the cecal body and initiated the important aborally propagated progressive pattern responsible for the transit of ingesta from the cecum to the RVC. A separate mechanism for the transit of gas was not identified. In the RVC, infrequent, nondirectional, low-amplitude segmental pressure peaks (0.12 +/- 0.06/min), and aborally progressive coordinated pressure peaks originating at the beginning of the RVC (0.09 +/- 0.02/min), occurred.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   
978.
Significant reductions in worm burdens were achieved in lambs treated with dialysed transfer factor and challenged with 10,000Haemonchus contortus larvae, when compared with challenged control animals. Non-dialysed transfer factor, from the same leucocyte pool, produced no protection, but was successful in reducing worm burdens when given after a primary infection of 1,000 H. contortus larvae with subsequent challenge of 10,000 larvae.While the results confirmed the previously reported inconsistencies of transfer factor activity, the histological abomasla changes in all the dialysed and non-dialysed transfer factor treated groups, irrespective of measurable effects on worm burdens, were consistent and corresponded to immediate type hypersensitivity responses.The similarity of these responses with self cure in haemonchosis and the possibility of genetic factors influencing the quantitative expression of protection to the effects of transfer factor treatments is discussed.  相似文献   
979.
Tetralogy of Fallot in the dog   总被引:1,自引:0,他引:1  
  相似文献   
980.
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