Flea (Ctenocephalides felis) control efficacy of topical indoxacarb on dogs subsequently bathed with a chlorhexidine–ketoconazole shampoo          下载免费PDF全文

RD Armstrong  JE Liebenberg  K Heaney  F Guerino 《Australian veterinary journal》2015,93(8):293-294

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Intestinal M cells: a pathway for entry of reovirus into the host   总被引：45，自引：0，他引：45  

J L Wolf  D H Rubin  R Finberg  R S Kauffman  A H Sharpe  J S Trier  B N Fields 《Science (New York, N.Y.)》1981,212(4493):471-472

Thirty minutes after inoculation of reovirus type 1 into the intestinal lumen of the mouse, viruses were found adhering to the surface of intestinal M cells but not other epithelial cells. Within 1 hour, viruses were seen in the M cell cytoplasm and were associated with mononuclear cells in the intercellular space adjacent to the M cell. These findings suggest that M cells are the site where reovirus penetrates the intestinal epithelium.  相似文献   

Alcohol-induced tolerance in mitochondrial membranes     

H Rottenberg  A Waring  E Rubin 《Science (New York, N.Y.)》1984,223(4632):193-194

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Hepatic microsomal enzymes in man and rat: induction and inhibition by ethanol   总被引：10，自引：0，他引：10  

E Rubin  C S Lieber 《Science (New York, N.Y.)》1968,162(854):690-691

The feeding of ethanol increased significantly the activities of hepatic pentobarbital and benzpyrene hydroxylases in rats, and, in human volunteers, doubled pentobarbital hydroxylase activity. In vitro ethanol inhibited aniline, pentobarbital, and benzpyrene hydroxylases. These data may explain, at least in part, the increased tolerance of alcoholics to sedatives when sober, and the enhanced sensitivity to sedatives when inebriated.  相似文献   

Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product.   总被引：131，自引：0，他引：131  

D P Bottaro  J S Rubin  D L Faletto  A M Chan  T E Kmiecik  G F Vande Woude  S A Aaronson 《Science (New York, N.Y.)》1991,251(4995):802-804

Hepatocyte growth factor (HGF) is a plasminogen-like protein thought to be a humoral mediator of liver regeneration. A 145-kilodalton tyrosyl phosphoprotein observed in rapid response to HGF treatment of intact target cells was identified by immunoblot analysis as the beta subunit of the c-met proto-oncogene product, a membrane-spanning tyrosine kinase. Covalent cross-linking of 125I-labeled ligand to cellular proteins of appropriate size that were recognized by antibodies to c-met directly established the c-met product as the cell-surface receptor for HGF.  相似文献   

Biomechanical mechanism of fabric softness discrimination     

Jiyong Hu  Xin Ding  Rubin Wang 《Fibers and Polymers》2007,8(4):372-376

“Softness” is one of the primitive terms describing the physical and sensory attributes of fabric, however, the information for its physiological mechanism compared to statistical physical factors of fabric softness is scarce. To explain the biomechanical and the potential neurophysiological phenomenon for exploring fabric softness, a finger-fabric finite element model is used to conduct an active contact simulation analysis. The effects of surface friction index and compression modulus of fabric on softness discrimination are investigated. The interests of the study are in the contributions of these fabric variables to the changing contact area, interfacial friction shear stress and contact pressure distributions, which are significant cognitive variables or stimulus parameters in peripheral neural levels documented by prior observations. The mechanistic data for fingerpad-fabric interaction indicate that the basis for the perception of softness of flexible and bulk fabric is likely on the spatial variation of the pressure and shear stress on the skin resulting from the surface friction index and compression property of fabric. These conclusions suggest that devices for the haptic rendering of fabric softness, based on vibration result from surface roughness, is not sufficient to perceive the soft-touch feel of fabric as a result of the cues with lack information for the changing contact area by touch.  相似文献   

Capability and limitation in evaluation on perceived fabric softness by three types of sensory modality     

Xudong?YangEmail author  Jiyong?Hu  Xin?Ding  Rubin?Wang 《Fibers and Polymers》2014,15(12):2651-2657

With an increasing online transaction of textile products and the current inaccessibility of their tactile properties to consumers, it is necessary to know the feasible manners in which the fabric softness sensation was perceived. Therefore, this study examined the accessibility of the tactile softness of fabrics by three different modalities, i.e. touch only, vision only (viewing video with fabric fluttering in a wind) and touch-vision bimodality. To compare the perceived softness sensation by three sensory modalities, two blocks of psychophysical experiment procedures were designed. The rating values were used to analyze the consistency of perceived softness magnitude among three sensory modalities, and to explore the physical determinants corresponding to each of three modalities. Meanwhile, both the just noticeable difference (JND) and the Webber fraction were calculated and compared among three different modalities. The results showed that it was statistically consistent of the magnitude of perceived softness sensation among three sensory modalities. The main physical determinants of perceived softness sensation were similar among three sensory modalities, whereas their contribution proportion depended on the specific modality. Psychometrically, the detectability by vision only were lower than that by touch only or touch-vision bimodality, and the discriminability by two modalities with tactual information was superior to that by vision only. Generally, it was concluded that blocking the view of the panelists was not a requirement for estimation on perceived softness intensity of fabrics, while in discrimination task the method with visual information couldn’t replace that with tactual information.  相似文献   

Traumatic tympanic bulla fracture     

J. A. Rubin  S. E. Kim  N. J. Bacon 《The Journal of small animal practice》2013,54(11):605-609

A Pekingese dog was presented for evaluation of head trauma with ventral head and neck swelling, puncture wounds, palpable mandibular fractures, and loss of menace, severe miosis, and loss of palpebral reflex of the right eye. Computed tomography confirmed multiple mandibular and zygomatic fractures, a right ear canal avulsion, and a complete right tympanic bulla fracture with ventral displacement. The tympanic bulla fracture was managed conservatively. Topical lubrication and antibiotic ointment was prescribed for the right eye. A subtotal hemimandibulectomy was performed to address the mandibular fractures. A temporary oesophagostomy feeding tube was placed. No short‐term complications developed as a result of the fractured bulla and avulsed ear canal being left in situ, and no complications were reported 18 months after the injury. To the authors’ knowledge this is the first report of a traumatic tympanic bulla fracture in the dog.  相似文献   

Effect of setting a maximum milking time,from peak lactation,on production,milking time and udder health     

JG Jago  JE McGowan  JH Williamson 《New Zealand veterinary journal》2013,61(5):246-252

Abstract

AIM: To examine the effect of setting a maximum milking time, from peak lactation until drying-off, on production, duration of milking, and udder health of dairy cows.

METHODS: Forty cows were assigned in twin-pairs to be either milked until cups were removed at a milk flow-rate threshold of 0.35 kg/minute (Control), or until cups were removed at a milk flow-rate threshold of 0.35 kg/minute, or maximum time, whichever came first (MaxT). The maximum time was set by determining the milking time of the 70th percentile cow when ranked from fastest to slowest, irrespective of yield. The milking routine was typical of that practised on dairy farms in New Zealand, and involved no pre-milking preparation. The study began at peak lactation (68 (SD 7) days in milk; DIM) and continued for 26 weeks. Duration of milking and milk yield were measured for each milking. Composition of milk was determined from weekly herd tests, and milk quality from fortnightly somatic cell counts (SCC). Completeness of milking and teat condition were assessed during the study. The bacterial status of quarter milk samples was determined at the beginning and end of the study, and all treated cases of clinical mastitis recorded. ANOVA was used to examine the effect of treatment group on variables of interest.

RESULTS: Total milk, fat and protein yields during the study period did not differ between treatments. On average, 30.3% of the morning and 27.6% of the afternoon milkings of MaxT cows reached the maximum time at which cups were removed, and were therefore shortened. While the average milking time of the slowest-milking cow was longer for the Control compared with MaxT group in Weeks 1–18, the average milking time did not differ between treatments. There was no difference in overall SCC, and the incidence of clinical mastitis, or the percentage of infected quarters at drying-off, was similar for the MaxT and Control cows.

CONCLUSION: The results show that setting a maximum milking time can reduce the milking time of slower-milking cows in a herd without compromising overall herd production and udder health.

CLINICAL RELEVANCE: Although the numbers of cows in the study were small there was no evidence of a major increase in SCC, or subclinical or clinical mastitis when a maximum milking time was set for slower-milking cows.  相似文献   

Continuous non‐destructive monitoring of Cyperus rotundus development using a minirhizotron     

T Shilo  B Rubin  J E Ephrath  H Eizenberg 《Weed Research》2013,53(3):164-168

A new method for non‐destructive monitoring of the subsurface development of Cyperus rotundus (purple nutsedge) is described. A minirhizotron (MR) system was adopted for use to observe vegetative growth of the weed in a net‐house and under field conditions. In particular, the key stages of tuber production and sprouting were monitored and quantified. The MR system allowed non‐destructive repeated measurements of the key stages in C. rotundus subsurface development, serving as a both quantitative and qualitative tool in the study of C. rotundus. A comparison between the MR method and a destructive method revealed that the former reduces experimental variance, thus providing a more accurate prediction of the sprouting process. The techniques presented in the current study offer advanced methodologies for continuous monitoring of C. rotundus development under the soil surface. The novelty of this method lies in its simplicity and efficiency, allowing continuous observation of specific organs of this noxious weed and potentially of other geophytes.  相似文献