Synthesis and testing of novel alternative oxidase (AOX) inhibitors with antifungal activity against Moniliophthora perniciosa (Stahel), the causal agent of witches' broom disease of cocoa,and other phytopathogens     

Mario RO Barsottini  Brbara A Pires  Maria L Vieira  Jos GC Pereira  Paulo CS Costa  Jaqueline Sanit  Alessandro Coradini  Fellipe Mello  Cidnei Marschalk  Eder M Silva  Daniele Paschoal  Antonio Figueira  Fbio HS Rodrigues  Artur T Cordeiro  Paulo CML Miranda  Paulo SL Oliveira  Maurício L Sfora  Marcelo F Carazzolle  Silvana A Rocco  Gonalo AG Pereira 《Pest management science》2019,75(5):1295-1303

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Cost effectiveness of extending and implementing a mastitis control program     

SL HILL  TJ NICHOLLS  MG BARTON  DJ OVEREND 《Australian veterinary journal》1990,67(12):469-469

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识别假劣、失效兽药的简易方法   总被引：1，自引：0，他引：1  

李松龄  陈冠军  马许 《中国兽药杂志》2005,39(4):51-52

介绍了识别假劣、失效兽药的简易方法,包括假劣兽药的外观识别和部分失效兽药的识别,可供畜牧养殖者参考.  相似文献   

Development of a Competitive Quantitative PCR Strategy for Evaluating the Expression Stability of 18s rRNA during In Vitro Maturation of Buffalo (Bubalus bubalis) Follicular Oocytes     

APS Aswal  TK Datta  S Raghav  S De  P Yadav  SL Goswami 《Reproduction in domestic animals》2007,42(2):195-201

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Thalidomide pharmacokinetics in sheep     

SL Smith  P Singh  D Harding  D Lun  JP Chambers 《New Zealand veterinary journal》2016,64(4):238-242

AIM: To determine the half life (T_1/2), time taken to reach maximum plasma concentration (T_max) and maximum plasma concentration (C_max) of thalidomide in sheep following I/V, oral and topical treatment with a single dose of thalidomide.

METHOD: Three groups of 4–6-month-old ram lambs were treated with thalidomide dissolved in dimethylsulphoxide (DMSO). The first group (n=10) was treated I/V with 100?mg thalidomide in 2?mL DMSO; the second group (n=8) received 400?mg thalidomide in 2?mL DMSO orally, and the third group (n=8) had 400?mg thalidomide in 4?mL DMSO applied topically. Plasma samples were collected up to 36 hours after treatment, snap-frozen at ?80°C and analysed for concentrations of thalidomide using high performance liquid chromatography.

RESULTS: Following I/V administration, T_1/2 was 5.0 (SEM 0.4) hours, volume of distribution was 3,372.0 (SEM 244.3) mL/kg and clearance was 487.1 (SEM 46.1) mL/hour.kg. Topical application of 400?mg thalidomide did not increase plasma concentrations. Following oral administration, thalidomide bioavailability was 89%, with T_1/2, T_max, and C_max being 7.2 (SEM 0.8) hours, 3.0 (SEM 0.4) hours and 1,767.3 (SEM 178.1) ng/mL, respectively.

CONCLUSION: Topical administration using DMSO as a solvent did not increase concentrations of thalidomide in plasma. The mean pharmacokinetic parameters determined following oral treatment with 400?mg of thalidomide were similar to those reported in humans receiving a single 400?mg oral dose (T_1/2 7.3 hours; T_max 4.3 hours and C_max 2,820?ng/mL). There is potential for thalidomide to be used as a model for the treatment of chronic inflammatory conditions in sheep, such as Johne's disease, where tumour necrosis factor alpha plays a pathogenic role.  相似文献   

Assessment of tillage strategies to decrease nitrate leaching in the Brimstone Farm Experiment, Oxfordshire, UK     

J. A. Catt  K. R. Howse  D. G. Christian  P. W. Lane  G. L. Harris  M. J. Goss 《Soil & Tillage Research》2000,53(3-4):185-200

Tillage may influence nitrate losses from agricultural soils. Losses of nitrate were measured in drainflow at 60 cm depth and in combined surface runoff and interflow in the A horizon (=surface layer flow) on hydrologically sealed plots with a two-year comparison (1988–1990) of shallow-tine cultivation vs. mouldboard ploughing. Ploughing increased concentrations and loadings of nitrate in drainflow and surface layer flow, especially in the first year. After these two years the shallow-tined plots were ploughed to plant winter beans (Vicia faba L.), and nitrate in drainflow then increased over the next three winters, slightly exceeding that from the plots which had been ploughed throughout for winter cereals. The composition of the surface layer flow did not show this effect, however. Calculations of net winter mineralisation of soil organic nitrogen showed that shallow-tine cultivation may have decreased mineralisation slightly compared with ploughing in the first two years. These calculations did not indicate any increase in mineralisation for two winters after the minimally cultivated plots were ploughed in autumn 1990, probably because the soil was then very dry. This increase was apparently delayed until the fifth winter (1992/1993), which was much wetter than any since autumn 1990. In the previous eight years (1980–1988) half of the plots had been ploughed and half had been direct drilled. Averaged over the five winters 1988/1989–1992/1993, the five measures of nitrate loss in drainflow from plots previously direct drilled were 6–57% more than from plots previously ploughed, and winter mineralisation was 20% more, with no evidence of any decline in either with time. The nitrate produced by mineralisation of organic matter conserved by the eight years of direct drilling was mainly lost by leaching or denitrification; it was of little or no benefit to the crops. The results suggest that in the long term more nitrate is leached from land subject to periods of minimal or zero tillage and ploughing than from land ploughed every year.  相似文献   

Mammary neoplasia in common brushtail possums: case report and retrospective identification of additional cases     

L Setyo  SL Donahoe  K Rose  D Spielman 《Australian veterinary journal》2020,98(6):243-246

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Unexpected results of a pilot throughfall exclusion experiment on soil emissions of CO<Subscript>2</Subscript>, CH<Subscript>4</Subscript>, N<Subscript>2</Subscript>O,and NO in eastern Amazonia     

José H. Cattânio  Eric A. Davidson  Daniel C. Nepstad  Louis V. Verchot  Ilse L. Ackerman 《Biology and Fertility of Soils》2002,36(2):102-108

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Surgical results and fertility following correction of vesicovaginal reflux in mares     

SL Jalim  AO McKinnon 《Australian veterinary journal》2010,88(5):182-185

Objective To evaluate the surgical results and fertility of mares bred at various intervals relative to surgical management of urovagina. Design Sixty-one mares underwent surgery to correct vesicovaginal reflux. Surgery was performed at varying times relative to breeding and postoperative fertility was evaluated. Results Five mares were lost to follow-up and a further four were electively not bred. Of the remaining 52 mares, seasonal pregnancy and live foaling rates were 67% (35/52) and 54% (26/48), respectively. When mares were bred in the same cycle as the surgery, the first cycle following surgery, the second cycle following surgery or the following breeding season after surgery the seasonal pregnancy rates were 89% (8/9), 63% (10/16), 67% (2/3) and 63% (15/24), respectively. After censoring four mares that died of natural causes pre-foaling, the foaling rates were 88% (7/8), 50% (7/14), 0% (0/3), 52% (12/23), respectively. All mares bred in the same cycle as surgery or in the next cycle were bred once only that season, so the pregnancy rate per cycle of 72% (18/25) was identical to the seasonal pregnancy rate. Conclusions Good fertility (comparable to a normal population of mares) was achieved following surgery and the results suggest that delaying breeding until the following breeding season is not necessary. In addition, breeding in the same cycle as surgical repair is a previously unreported technique that should be considered to maintain a yearly foaling interval.  相似文献   

Distal luxation of the patella in a horse     

MS Hall  SL Jalim  TM Russell 《Australian veterinary journal》2010,88(10):396-398

A 19-year-old Thoroughbred gelding presented with sudden onset, non-weight bearing lameness in the right hindlimb. Radiography confirmed distal luxation of the patella, which was replaced into its normal anatomical location under general anaesthesia. There were no pathological sequelae noted on follow-up examination 9 months after the initial injury. To our knowledge, this is a rare manifestation of patellar luxation, only reported once previously in the equine literature.  相似文献