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排序方式： 共有1410条查询结果，搜索用时 296 毫秒
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Categorical perception of a natural stimulus continuum: birdsong 总被引：2，自引：0，他引：2
A fundamental issue in perception and communication is how continuously varying stimuli are partitioned into discrete categories. In swamp sparrow songs, note duration is a critical feature distinguishing two note categories with different roles in song construction. Pairs of songs with initial notes from different categories contrast more in their effects on territorial males than song pairs with initial notes differing by the same amount but taken from within one note category. The results indicate categorical perception by wild swamp sparrows. 相似文献
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Nelson PG 《Science (New York, N.Y.)》1988,240(4857):1351-1352
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Nelson B 《Science (New York, N.Y.)》1967,157(3785):173-176
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Morphogenesis of the polarized epithelial cell phenotype 总被引：152，自引：0，他引：152
Polarized epithelial cells play fundamental roles in the ontogeny and function of a variety of tissues and organs in mammals. The morphogenesis of a sheet of polarized epithelial cells (the trophectoderm) is the first overt sign of cellular differentiation in early embryonic development. In the adult, polarized epithelial cells line all body cavities and occur in tissues that carry out specialized vectorial transport functions of absorption and secretion. The generation of this phenotype is a multistage process requiring extracellular cues and the reorganization of proteins in the cytoplasm and on the plasma membrane; once established, the phenotype is maintained by the segregation and retention of specific proteins and lipids in distinct apical and basal-lateral plasma membrane domains. 相似文献
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Heparin is an acceleratory cofactor for antithrombin, a circulating inhibitor of blood coagulation enzymes. The presence of heparin on blood vessel walls is believed to contribute to the nonthrombogenic properties of those surfaces. In apparent opposition to this function, heparin was found to greatly accelerate the in vitro inactivation of antithrombin by neutrophil elastase. Inactivation rates in solution were potentiated several hundredfold by specific heparin fractions with anticoagulant activity. Although the data suggest that a heparin-antithrombin complex is essential for the inactivation by elastase to occur, the enzyme itself interacts tightly with heparin. These results suggest a mechanism which, if operating in vivo, could lead to a localized neutralization of the anticoagulant function of heparin at the endothelial surface. 相似文献