A Comparison of Surgical Training with Live Anesthetized Dogs and Cadavers     

LARRY G. CARPENTER DVM    DONALD L. PIERMATTEI DVM  PhD  Dipiomate ACVS    MOWAFAK D. SALMAN BVMS  PhD  Dipiomate ACVPM    E. CHRISTOPHER ORTON DVM  PhD  Dipiomate ACVS    A. WENDELL NELSON DVM  PhD  Dipiomate ACVS    DANIEL D. SMEAK DVM  Dipiomate ACVS    PAUL B. JENNINGS Jr.  VMD  MS  Dipiomate ACVS ROBERT A. TAYLOR DVM  MS  Dipiomate ACVS 《Veterinary surgery : VS》1991,20(6):373-378

Cadavers were compared with live anesthetized dogs for their effectiveness as models for surgical training of veterinary medical students. One group of students was trained using cadavers, and a peer group was trained using live anesthetized dogs. Both groups then performed an intestinal anastomosis using a live subject. The time to completion of the procedure was recorded. The anastomoses and celiotomy closures were evaluated. Each anastomosis was isolated and pressure tested. Reviewers blindly scored each surgical team's performance based on actual inspection of the surgical site and on viewing videotapes of the procedure. The participants' attitudes toward the use of live animals in teaching and research were documented before and after training. No statistically significant differences could be detected between the two groups. The results suggest that some substitution of cadavers for live dogs in surgical training might be feasible.  相似文献   

A Comparison of Injectable Anesthetic Combinations in Horses   总被引：4，自引：0，他引：4  

N. S. MATTHEWS DVM  Diplomate ACVA    S. M. HARTSFIELD DVM  MS  Diplomate ACVA    J. L. CORNICK DVM  MS    J. D. WILLIAMS PhD  A. BEASLEY AHT 《Veterinary surgery : VS》1991,20(4):268-273

Six combinations of injectable anesthetic agents were administered to six adult horses in a Latin square design. The drug combinations were xylazine-ketamine, xylazine-butorphanol-ketamine, xylazine-tiletamine-zolazepam, xylazine-butorphanol-tiletamine-zolazepam, detomidine-ketamine, and detomidine-butorphanol-ketamine. Measured variables were heart rate, respiratory rate, systolic blood pressure, arterial pH (pHa), PaCO2, PaO2, recumbency time, and number of attempts necessary to stand. Quality of induction and recovery, muscle relaxation, and response to stimulus were evaluated subjectively. The horses required significantly more attempts to stand after administration of xylazine-tiletamine-zolazepam, xylazine-butorphanol-tiletamine-zolazepam, and detomidine-ketamine than after xylazine-ketamine, xylazine-butorphanol-ketamine, or detomidine-butorphanol-ketamine. Mean recumbency times varied from 23.0 minutes with xylazine-ketamine to 41.3 minutes with xylazine-butorphanol-tiletamine-zolazepam. There were significant differences in mean heart rates at minute 15, mean respiratory rates at minutes 5, 10 and 15, and mean systolic blood pressures at minute 10 of anesthesia. There were no significant differences in pHa, PaCO2 or PaO2.  相似文献   

Intracavitary Cisplatin Chemotherapy Experience with Six Dogs   总被引：1，自引：0，他引：1  

Antony S. Moore MVSc    Claudia Kirk DVM  Aglaia Cardona DVM 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1991,5(4):227-231

Six dogs with a median age of 7 years (range = 5-14 years) were presented for signs referable to thoracic or abdominal effusion associated with neoplasia of the body cavities. Intracavitary cisplatin was administered at 50 mg/m2 every 4 weeks for a median of 2.5 treatments (mean = 3, range = 1-6). Three dogs with pleural mesothelioma had complete resolution of effusion for 289, 129, and greater than 306 days without evidence of tumor growth. Resolution of effusion occurred after one treatment in two dogs and after two treatments in one dog. In three dogs with carcinomatosis of unknown origin, complete responses was seen in two dogs after one treatment for 255 and greater than 807 days, respectively. Intracavitary chemotherapy with cisplatin was associated with palliation and control of malignant pleural and/or abdominal effusion in five of six dogs. Toxicity was minimal, and this method of therapy should be further explored in dogs with similar malignancies.  相似文献   

Pathophysiology of Degenerative Joint Disease     

Paul McClellan DVM 《Journal of Equine Veterinary Science》1991,11(3)

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MAGNETIC RESONANCE IMAGING FEATURES OF MULTILOBULAR OSTEOCHONDROSARCOMA IN 3 DOGS     

David  Lipsitz  DVM  Robin E.  Levitski  DVM  Wayne L.  Berry  BVSc  MMedVet 《Veterinary radiology & ultrasound》2001,42(1):14-19

Three dogs with multilobular osteochondrosarcoma of the skull were evaluated using magnetic resonance (MR) imaging. Spin echo T1, T2, proton weighted and post contrast T1W images were obtained with a 1.5 Tesla magnet. The MR imaging findings were similar in all three dogs with mixed signal intensities in the T1W, T2W and proton weighted images and fairly large areas of contrast enhancement in the post contrast T1W images. The extent of brain and soft tissue involvement were well delineated and provided useful information concerning surgical planning. MR imaging provided a useful method of evaluating dogs with skull tumors.  相似文献   

A Comparison of Arterial and Lingual Venous Blood Gases in Anethetized Dogs     

A.E. Wanger DVM  MS    W.W. Muir III  DVM  Phd R.M. Bednaraki DVM  MS 《Journal of Veterinary Emergency and Critical Care》1991,1(1):14-18

The purpose of this study was to determine whether lingual vanous blood gas samples reflect arterial acid-base gas status in anethetized dogs. Heparinized blood samples were drawn simultaneously from the lingual vein and a peripheral artery in 50 anestheized dogs that were clinical surgical patients, as well as from four experimental dogs in which hemorrahaic shock was being studied. Blood pH, oxygen tension (PO₂), and bicarbonate (HCO_3-)) from the two sources in clinical patients showed significant liner correlation, although arterial PO₂)(PaO₂)) tended to be approximately 110mm Hg higher than lingual venous PO₂). During hemorrahgic shock, however, PaO₂) and PaCO₂) were significantly different from lingual venous PO₂) and PCO₂), Lingula venous blood gas analysis may be useful in assessing acid-base and blood gas status in routline cases, but should not be relied upon in dogs with low cardiac output or poor perfusion.  相似文献   

Intraperitoneal Circulation and Drainage in the Dog   总被引：1，自引：0，他引：1  

GISELLE HOSGOOD BVSc  MS  FACVSc    S. KATHLEEN SALISBURY DVM  MS  DiplomateACVS    H. DAN CANTWELL DVM  MS  DiplomateACVR  DENNIS B. DENICOLA DVM  PhD  DiplomateACVP 《Veterinary surgery : VS》1989,18(4):261-268

The patterns of dispersion and drainage of a low viscosity, oil-based contrast medium within the peritoneal cavity were examined in 12 normal dogs. Intraperitoneal injection of contrast medium was cranial or caudal and drainage was by the sump-Penrose or open peritoneal method. Radiographs were made over a 96 hour period, before and after peritoneal drainage was established. Each dog was euthanatized and necropsied. The contrast medium was dispersed throughout the peritoneal cavity 15 to 30 minutes after cranial injection and 1 to 2 hours after caudal injection. Most of the contrast medium drained within 6 hours after open peritoneal drainage and within 24 to 48 hours after sump-Penrose drainage. At necropsy, there was complete encasement of all sump-Penrose drains and partial occlusion of all open peritoneal incisions by omentum adhered to the abdominal wound edges. Peritonitis was not grossly evident, but all dogs showed histologic evidence of an acute inflammatory reaction associated with the drain or wound edge.  相似文献   

Chronic progressive lymphedema in draft horses     

Gregory Ferraro DVM 《Journal of Equine Veterinary Science》2003,23(5):189-190

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THE NON-CARDIAC DISTRIBUTION OF ^99mTC-METHOXY-ISOBUTYL-ISONITRILE (SESTAMIBI) IN NORMAL BEAGLES     

Phillip F.  Steyn  BVSc  MRCVS  MS  Gregory  Ogilvie  DVM 《Veterinary radiology & ultrasound》1995,36(2):160-163

Technetium-99m methoxy-isobutyl-isonitrile (sestamibi) is a radiophartnaceutical used for the evaluation of myocardial perfusion. Increased uptake of sestamibi has also been documented in tumors. The objective of this study was to document the extracardiac biodistribution of ^99mTc sestamibi in the normal dog. Nine normal beagles were given 0.35 mCi/kg ^99mTc sestamibi intravenously, and 60 second images were made of the entire body at 1 hour post injection. A defined distribution pattern was recognized, with good visualization of the heart, liver, gallbladder, small intestine, kidneys, urinary bladder, popliteal lymph nodes, parotid salivary glands and zygomatic salivary glands. Splenic uptake was not seen.
Target to background ratios were calculated for all the regions listed, using background regions-of-interest with the smallest coefficient of variance for the denominator. The mean, range and standard deviation of these ratios are given.  相似文献   

Temporary Bile Diversion in Cats with Experimental Extrahepatic Bile Duct Obstruction     

DARIEN LAWRENCE BSc  BVSC    JAMIE R. BELLAH DVM  Dipiomate ACVS    D. J. MEYER DVM  Dipiomate ACVIM  Dipiomate ACVP  L. ROTH DVM  PhD  Dipiomate ACVP 《Veterinary surgery : VS》1992,21(6):446-451

The use of a cholecystostomy catheter for temporary bile diversion was investigated in four cats with experimentally induced extrahepatic bile duct obstruction. Eighteen days after ligation of the common bile duct, a 6.5 F accordion catheter was placed in the gallbladder with a 22 g Hawkins needle-guide system through a paracostal incision. Biochemical parameters and fasting serum bile acids were monitored for 16 days. There were significant decreases in mean total bilirubin, aspartate aminotransferase, and fasting serum bile acids within 72 hours of bile diversion, and in mean alanine aminotransferase within 96 hours. Attitude and appetite improved, and the catheter was tolerated well. Positive bile cultures developed in three cats. Histologic changes in the gallbladder included mucosal ulcerations, a mixed inflammatory cellular infiltration, and fibrosis of the submucosa.  相似文献