Tracheobronchopathia osteochondroplastica in a dog     

Sellon RK  Johnson JL  Leathers CW  Sporn T  Beckley JC 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2004,18(3):359-362

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Hepatic abscesses in three horses     

Sellon DC  Spaulding K  Breuhaus BA  Katz L  Mealey R 《Journal of the American Veterinary Medical Association》2000,216(6):882-7, 864-5

Hepatic abscesses were diagnosed in 3 adult horses. Two were < 4 years old and had evidence of concurrent immune-mediated conditions, including aseptic arthritis, immune-mediated thrombocytopenia, and immune-mediated anemia. Predisposing factors for hepatic abscess formation in these horses included prior abdominal surgery, proximal duodenitis/jejunitis, inflammatory bowel disease, and a penetrating foreign body in the large colon. Serum hepatic enzyme activities were within or slightly greater then reference limits in all 3 horses. The most pronounced and consistent abnormalities on CBC and serum biochemical analyses were hyperproteinemia, hyperglobulinemia, and a decreased albumin-to-globulin concentration ratio. Hepatic ultrasonography identified hepatic abscesses in all 3 horses. A variety of bacteria were isolated from these abscesses, including Staphylococus aureus and Bacteroides fragilis. One horse developed septic tibiotarsal arthritis, presumably as a result of intermittent bacteremia. Despite aggressive medical treatment, all horses were euthanatized because of a worsening condition and poor prognosis.  相似文献   

Thrombocytosis in 24 Horses (1989–1994)     

Debra C. Sellon DVM  Phd    Jay F. Levine  Kate Palmer  Everett Millikin  Carol Grindem  Patrice Covington 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1997,11(1):24-29

The records of horses presented to the Veterinary Teaching Hospital of North Carolina State University College of Veterinary Medicine between January 1, 1989 and April 30, 1994 were evaluated to determine risk factors associated with thrombocytosis. Of the 2,346 horses for which a CBC was performed, 24 (1.0%) had a platelet count > 400,000/μL. Demographic, diagnostic, physical examination, and clinicopathologic variables from these cases were compared with a reference population consisting of 189 horses with a normal platelet count presenting during the same period. Infectious/inflammatory disorders were observed more commonly in horses with high platelet counts than in horses with normal platelet counts. Initial independent evaluation of demographic variables revealed that horses more than 3 years of age, females, and geldings were less likely to have thrombocytosis than were younger horses or stallions. Independent analysis of clinicopathologic variables revealed that horses with thrombocytosis were more likely to have hyper-fibrinogenemia, leukocytosis, hypoproteinemia, and anemia than were horses with normal platelet counts. Physical examination parameters associated with thrombocytosis included tachycardia and pyrexia. In the final multivariable model, the variables with the strongest association with thrombocytosis included leukocytosis, anemia, and hyper-fibrinogenemia. Thrombocytosis rarely causes clinical problems in horses and is not likely to require specific antiplatelet therapy. The strong association of thrombocytosis with infectious/inflammatory disorders, however, should lead clinicians to suspect these types of conditions in horses with high platelet counts.  相似文献   

GASTROGASTRIC INTUSSUSCEPTION IN A DOG     

Raymond A.  Huml  MS  Linda J.  Konde  DVM  Rance K.  Sellon  DVM  Lisa J.  Forrest  VMD 《Veterinary radiology & ultrasound》1992,33(3):150-153

A three-year-old, intact male, Rottweiler is presented with a gastrogastric intussusception. This is one of only two known reports of gastrogastric intussusception in the dog. Lateral and ventrodorsal radiographs and ultrasound revealed a gastric mass, however the diagnosis of gastrogastric intussusception was made during surgery. The patient in this report had no associated tumor and the pyloric antrum was the intussusceptum. Cause of the intussusception is unknown.  相似文献   

Diagnosis of naturally occurring toxoplasmosis by bronchoalveolar lavage in a cat     

Brownlee L  Sellon RK 《Journal of the American Animal Hospital Association》2001,37(3):251-255

A 5-year-old cat presented with a history of fever and respiratory distress of 7 days' duration. The cat did not respond to initial symptomatic treatment. Through use of a bronchoalveolar lavage (BAL) technique, the diagnosis of toxoplasmosis was obtained rapidly without evidence of adverse effects to the cat. Antemortem diagnosis of naturally occurring active Toxoplasma gondii infection can be difficult in cats. Identification of organisms obtained by BAL may be beneficial in the diagnosis of feline toxoplasmosis.  相似文献   

Improving the efficacy of nuclear polyhedrosis virus and Bacillus thuringiensis against Helicoverpa spp. with ultra-violet light protected petroleum spray oils on cotton crops in Australia     

RK Mensah  W Liang  D Gibb  R Coates  D Johnson 《国际虫害防治杂志》2013,59(2):101-109

Nuclear polyhedrosis virus (NPV) and Bacillus thuringiensis (Bt) are the most commonly used biopesticides for the control of Helicoverpa spp. larvae on cotton crops in Australia. The performance of NPV and Bt against Helicoverpa spp. larvae on cotton crops, is inconsistent and at times totally unsatisfactory against high densities of Helicoverpa spp. larvae. We determined the effect of mixing petroleum spray oils, containing ultra-violet light absorbing compounds, with NPV and Bt for efficacy against Helicoverpa spp. larvae, levels of cotton plant damage, and persistence of efficacy. The study showed that the efficacy and persistence of NPV and Bt were increased when mixed with petroleum spray oil (PSO?–?Canopy®) at the rate of 2% (v/v). In the field experiments, mixing NPV with 1 and 2% (v/v) PSO, increased Helicoverpa spp. mortality from 25.9 to 31.5 and 44.8%, respectively. Similarly, the mortality caused by Bt, when mixed with 1 and 2% (v/v) PSO, was increased from 31.5 to 36.0 and 48.2%, respectively. In addition, 1 and 2% PSO mixtures with NPV increased persistence of efficacy from 1.1 to 1.6 and 2.5 days, respectively, whilst persistence of Bt was increased from 1.5 to 1.8 and 2.6 days, respectively. In another study using potted cotton plants, in which the plants were left outdoors throughout the study, the average NPV induced mortality of first instar Helicoverpa larvae was increased from 20.9% to 35.9 and 43.4% by 1 and 2% (v/v) PSO, respectively. Persistence of NPV efficacy was enhanced by 2 and 3.1 times by 1 and 2% (v/v) PSO, respectively. Similarly, Bt induced mortality of Helicoverpa larvae was increased by 1 and 2% PSO from 68.1 to 78.8 and 83.2%, respectively, and the persistence of Bt efficacy was enhanced 1.3?–?2.0 times, respectively. In a mesh house study, young cotton plants, treated with a PSO/biopesticide mixture, suffered less leaf damage than cotton plants treated with the biopesticides alone. In conclusion, the results of this study showed synergies from the combined use of UV protected PSO and NPV or Bt, against Helicoverpa spp. larvae on cotton. Such a biopesticide-PSO combinations could be a useful tool for IPM program in cotton.  相似文献   

Differential Ovarian Morphometry and Follicular Expression of BMP15, GDF9 and BMPR1B Influence the Prolificacy in Goat     

RK Pramod  SK Sharma  A Singhi  S Pan  A Mitra 《Reproduction in domestic animals》2013,48(5):803-809

The variation in the kidding size of Black Bengal and Sirohi breed of goats makes them an interesting genetic material to study the underlying genetic mechanism of prolificacy. Accordingly, we studied the comparative ovarian morphometry including disparity in numbers of antral follicles of different sizes between these two breeds. Further, we evaluated the differential expression of the important candidate genes (viz., BMP15, GDF9 and BMPR1B) known to influence the ovulation rates and the prolificacy. The ovaries of Black Bengal (n = 20) goat were lighter (p < 0.01) in weight and smaller (p < 0.01) in diameter than those of Sirohi (n = 19) goats but possessed more numbers (p < 0.05) of corpus luteum (CL), large and small antral follicles. Quantitative real‐time PCR (RT‐qPCR) analysis revealed differential expression of mRNAs encoding for the BMP15 and GDF9. Small antral follicles of Black Bengal goats expressed 2.78‐fold more (p < 0.05) of BMP 15 than those of Sirohi goat. Expression of BMP15 (p < 0.01) and GDF9 (p < 0.05) mRNAs was more abundant in the small than the large antral follicles of Black Bengal goat. The more numbers of antral follicles per unit of ovarian mass and differential expression of BMP15 and GDF9 may serve as an important clue for higher prolificacy.  相似文献   

Expression of CYP26b1 and Related Retinoic Acid Signalling Molecules in Young,Peripubertal and Adult Dog Testis     

VR Kasimanickam  RK Kasimanickam 《Reproduction in domestic animals》2013,48(1):171-176

The objective of the study was to elucidate mRNA expression of CYP26b1 (cytochrome P450, family 26, subfamily B, polypeptide 1) and signalling molecules ALDH1 (aldehyde dehydrogenase 1), CRABPII (cellular retinoic acid‐binding protein II), RARα (retinoic acid receptor alpha) and STRA8 (stimulated by retinoic acid gene 8) in dog testis from different post‐natal developmental ages. Testicular tissue samples were collected from medium‐sized mixed breed dogs at different ages such as young (<4 months; N = 4), peripubertal (4–8 months; N = 3) and adult (>8 months; N = 4) were used to evaluate relative mRNA expression. Genes of RA‐degrading enzyme CYP26b1, ALDH1 involved in RA synthesis and genes of carrier protein CRABPII involved in RA metabolism were turned on during the post‐natal testicular development in dogs. Their expression pattern differs at different developmental ages (p < 0.05), and the levels of mRNA expression were compensated towards a normal developmental response for the sexual maturity and continuous spermatogenesis. The mRNA expression of RARα, one of the RA receptors participates in RA signalling in connection to spermatogenesis, was recorded in young and adult stages at varying degree. STRA8 is one of the responsive genes with regard to meiosis, and this functional gene product was expressed in all ages with the changing level (p < 0.01). In summary, the expression pattern of RA signalling molecules differed from young to adult ages, and it is expected that these changes are to compensate towards a normal developmental response for the sexual maturity and continuous spermatogenesis.  相似文献