Prostaglandin Endoperoxide Synthase 2 (PTGS2) and Prostaglandins F2α and E2 Synthases (PGFS and PGES) Expression and Prostaglandin F2α and E2 Secretion Following Oestrogen and/or Progesterone Stimulation of the Feline Endometrium     

MJ Siemieniuch  E Jursza  MP Kowalewski  M Majewska  DJ Skarzynski 《Reproduction in domestic animals》2013,48(1):72-78

Sex steroids in synergy with prostaglandins (PG) are involved in the regulation of cyclic ovarian function. In this study, we investigated the mRNA expression of three genes involved in arachidonic acid (AA) metabolism and hence PG production in domestic cats: PG‐endoperoxide synthase (PTGS2), PGF_2α synthase (PGFS) and PGE₂ synthase (PGES). Feline endometria (n = 16) were collected at oestrus and mid and late phases of pseudopregnancy. In addition, the effects of E₂ and/or P₄ on PG secretion and gene expression on endometrial explants were studied in an in vitro culture system. Expression levels of all examined genes were up‐regulated at the mid phase of pseudopregnancy. The effects of E₂ and/or P₄ treatment on both PG secretion and expression of the genes were observed after 12 h of culture. Expression of PGES was significantly up‐regulated by E₂ plus P₄ at oestrus and the mid phase of pseudopregnancy and was also up‐regulated by a single treatment with P₄ at late pseudopregnancy (p < 0.05). Simultaneous incubation with E₂ and P₄ up‐regulated PTGS2 gene expression at oestrus and mid‐luteal phase (p < 0.05). Progesterone plus E₂ significantly increased PGE₂ secretion at oestrus and the mid phase of pseudopregnancy. However, treatment with E₂ and/or P₄ affected neither PGF_2α secretion nor PGFS expression at any phase after 12 h of culture. The overall findings indicate that genes involved in PG synthesis are up‐regulated at the mid phase of pseudopregnancy. An increase in PGE₂ secretion and up‐regulation of PGES and PTGS2 are the main responses of the endometrium to treatment with E₂ and P₄ at oestrus and the mid phase of pseudopregnancy in the cat. These data support the hypothesis that ovarian sex steroids via endometrial PGE₂ are involved in endocrine homoeostasis, especially at oestrus and the mid, but not the late, phase of pseudopregnancy in cats.  相似文献   

A Case of Successful Pregnancy in a Ewe with Uterus Didelphys     

DJ Carr  RP Aitken  JS Milne  AL David  JM Wallace 《Reproduction in domestic animals》2013,48(5):e78-e80

Uterus didelphys is a rare congenital abnormality of the reproductive tract. Although it occurs in various species, there are no published reports describing pregnancy outcome in association with this abnormality. Herein we describe a case of successful unilateral singleton pregnancy in a ewe incidentally found to have uterus didelphys during the course of a biomedical research study. The pregnancy was established using assisted reproductive techniques and interrupted in late gestation, at which point the abnormality was identified. Serial ultrasound assessment of foetal biometry revealed a normal foetal growth trajectory. Despite a 45% reduction in placentome number, total placentome weight was near normal secondary to compensatory placentome growth and development. To our knowledge, this is the first detailed report of normal foetal growth in an animal with uterus didelphys and illustrates the ability of the ovine placenta to adapt to a reduced number of placentomes and maintain foetal nutrient supply.  相似文献   

Endocrine Regulation of the Establishment of Spermatogenesis in Pigs     

KC Caires  JA Schmidt  AP Oliver  J de Avila  DJ McLean 《Reproduction in domestic animals》2008,43(S2):280-287

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Oxalate‐degrading bacteria,including Oxalobacter formigenes,colonise the gastrointestinal tract of healthy koalas (Phascolarctos cinereus) and those with oxalate nephrosis     

KN Speight  M Houston‐Francis  M Mohammadi‐Dehcheshmeh  E Ebrahimie  S Saputra  DJ Trott 《Australian veterinary journal》2019,97(5):166-170

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Testing the efficacy of kitasamycin for use in the control and treatment of swine dysentery in experimentally infected pigs     

T La  ND Phillips  H Dunlop  K Lugsomya  F Coiacetto  DJ Hampson 《Australian veterinary journal》2019,97(11):452-464

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Anthelmintic resistance in gastrointestinal nematodes of dairy cattle in the Macalister Irrigation District of Victoria          下载免费PDF全文

SL Bullen  DS Beggs  PD Mansell  DJ Runciman  J Malmo  MC Playford  MF Pyman 《Australian veterinary journal》2016,94(1-2):35-41

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Micromechanical "Trampoline" magnetometers for use in large pulsed magnetic fields     

V Aksyuk  FF Balakirev  GS Boebinger  PL Gammel  RC Haddon  DJ Bishop 《Science (New York, N.Y.)》1998,280(5364):720-722

A silicon micromechanical magnetometer was constructed and successfully used in 60-tesla pulsed magnetic fields of less than 100-millisecond duration. The device is small, inexpensive to fabricate, and easy to use. It features a fast mechanical response (up to 50,000 hertz) and extremely high sensitivity yet is relatively robust against electrical and mechanical noise. Quantum oscillations in the magnetization of a 1-microgram sample of an organic superconductor, kappa-[bis(ethylenedithio)tetrathiafulvalene]2Cu(NCS)2, have been observed with this device.  相似文献   

Major compositional units of the moon: lunar prospector thermal and fast neutrons   总被引：2，自引：0，他引：2  

WC Feldman  BL Barraclough  S Maurice  RC Elphic  DJ Lawrence  DR Thomsen  AB Binder 《Science (New York, N.Y.)》1998,281(5382):1489-1493

Global maps of thermal and fast neutron fluxes from the moon suggest three end-member compositional units. A high thermal and low fast neutron flux unit correlates with the lunar highlands and is consistent with feldspathic rocks. The South Pole-Aitken basin and a strip that surrounds the nearside maria have intermediate thermal and fast neutron flux levels, consistent with more mafic rocks. There appears to be a smooth transition between the most mafic and feldspathic compositions, which correspond to low and high surface altitudes, respectively. The maria show low thermal and high fast neutron fluxes, consistent with basaltic rocks.  相似文献   

Platinum catalysts for the high-yield oxidation of methane to a methanol derivative   总被引：1，自引：0，他引：1  

RA Periana  DJ Taube  S Gamble  H Taube  T Satoh  H Fujii 《Science (New York, N.Y.)》1998,280(5363):560-564

Platinum catalysts are reported for the direct, low-temperature, oxidative conversion of methane to a methanol derivative at greater than 70 percent one-pass yield based on methane. The catalysts are platinum complexes derived from the bidiazine ligand family that are stable, active, and selective for the oxidation of a carbon-hydrogen bond of methane to produce methyl esters. Mechanistic studies show that platinum(II) is the most active oxidation state of platinum for reaction with methane, and are consistent with reaction proceeding through carbon-hydrogen bond activation of methane to generate a platinum-methyl intermediate that is oxidized to generate the methyl ester product.  相似文献   

Lunar Fe and Ti abundances: comparison of lunar prospector and clementine data   总被引：3，自引：0，他引：3  

RC Elphic  DJ Lawrence  WC Feldman  BL Barraclough  S Maurice  AB Binder  PG Lucey 《Science (New York, N.Y.)》1998,281(5382):1493-1496

The Lunar Prospector neutron spectrometer data correlate well with iron and titanium abundances obtained through analysis of Clementine spectral reflectance data. With the iron and titanium dependence removed, the neutron spectrometer data also reveal regions with enhanced amounts of gadolinium and samarium, incompatible rare earth elements that are enriched in the final phases of magma crystallization. These regions are found mainly around the ramparts of the Imbrium impact basin but not around the other basins, including the much larger and deeper South Pole-Aitken basin. This result confirms the compositional uniqueness of the surface and interior of the Imbrium region.  相似文献