Migration patterns leading to population change in the nonmetropolitan South     

Shelly FM  Roseman CC 《Growth and change》1978,9(2):14-21

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Effect of gentamicin sulfate dip on salmonella organisms in experimentally infected turkey eggs   总被引：2，自引：0，他引：2  

Y M Saif  S M Shelly 《Avian diseases》1973,17(3):574-581

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Evaluation of intestinal permeability and gluten sensitivity in Soft-Coated Wheaten Terriers with familial protein-losing enteropathy, protein-losing nephropathy, or both     

Vaden SL  Sellon RK  Melgarejo LT  Williams DA  Trogdon MM  VanCamp SD  Argenzio RA 《American journal of veterinary research》2000,61(5):518-524

OBJECTIVE: To evaluate intestinal permeability and gluten sensitivity in a family of Soft-Coated Wheaten Terriers (SCWT) affected with protein-losing enteropathy (PLE), protein-losing nephropathy (PLN), or both. ANIMALS: 6 affected adult dogs. PROCEDURE: Intestinal biopsy specimens, urine protein-to-creatinine ratio, serum concentrations of albumin and globulin, and concentration of alpha1-protease inhibitor in feces were evaluated before, during, and 13 weeks after daily administration of 10 g of gluten for 7 weeks. Eosinophils and lymphocytes-plasmacytes were enumerated in intestinal biopsy specimens. Intestinal permeability was evaluated before and during the sixth week of gluten administration via cellobiose-mannitol and chromium-EDTA absorption tests. RESULTS: Serum globulin concentration decreased significantly after prolonged administration of gluten. Although not significant, there was an increase in lymphocytes-plasmacytes and a decrease in eosinophils in intestinal biopsy specimens. Furthermore, these counts were greater than those reported for clinically normal dogs. Gluten administration did not increase intestinal permeability. CONCLUSIONS AND CLINICAL RELEVANCE: Daily administration of gluten was associated with a significant decrease in serum globulin concentration in SCWT affected with PLE or PLN, but other variables remained unchanged. Although enhanced wheat-gluten sensitivity may be one factor involved in the pathogenesis of PLE or PLN in SCWT, this syndrome does not appear to be the result of a specific sensitivity to gluten.  相似文献   

Hypercalcemia in cats: a retrospective study of 71 cases (1991-1997)     

Savary KC  Price GS  Vaden SL 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2000,14(2):184-189

A retrospective study was conducted to characterize the diseases, clinical findings, and clinicopathologic and ultrasonographic findings associated with hypercalcemia (serum calcium concentration >11 mg/dL) in 71 cats presented to North Carolina State University Veterinary Teaching Hospital. The 3 most common diagnoses were neoplasia (n = 21), renal failure (n = 18), and urolithiasis (n = 11). Primary hyperparathyroidism was diagnosed in 4 cats. Lymphoma and squamous cell carcinoma were the most frequently diagnosed tumors. Calcium oxalate uroliths were diagnosed in 8 of 11 cats with urolithiasis. Cats with neoplasia had a higher serum calcium concentration (13.5 ± 2.5 mg/dL) than cats with renal failure or urolithiasis and renal failure (11.5 ± 0.4 mg/dL; P <.03). Serum phosphorus concentration was higher in cats with renal failure than in cats with neoplasia ( P < .004). Despite the fact that the majority of cats with uroliths were azotemic, their serum urea nitrogen and creatinine concentrations and urine specific gravity differed from that of cats with renal failure. Additional studies are warranted to determine the underlying disease mechanism in the cats we identified with hypercalcemia and urolithiasis. We also identified a small number of cats with diseases that are not commonly reported with hypercalcemia. Further studies are needed to determine whether an association exists between these diseases and hypercalcemia, as well as to characterize the underlying pathophysiologic mechanism for each disease process.  相似文献   

Azadirachtin-based insecticide impairs testis morphology and spermatogenesis of the southern armyworm Spodoptera eridania (Lepidoptera: Noctuidae)     

Elton Luiz Scudeler  Bruno Vinicius Daquila  Shelly Favorito de Carvalho  Helio Conte  Carlos Roberto Padovani  Daniela Carvalho dos Santos 《Pest management science》2023,79(5):1650-1659

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Quantitative analysis of magnetic resonance images for characterization of blood-brain barrier dysfunction in dogs with brain tumors     

Erez Hanael  Shelly Baruch  Orit Chai  Liron Lishitsky  Tal Blum  Kira Rapoport  Marco Ruggeri  Zahi Aizenberg  Dana Peery  Nina Meyerhoff  Holger Andreas Volk  Steven De Decker  Andrea Tipold  Wolfgang Baumgaertner  Alon Friedman  Merav Shamir 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2023,37(2):606-617

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Cystoscopic-guided balloon dilation of a urethral stricture in a female dog     

Wood MW  Vaden S  Cerda-Gonzalez S  Keene B 《The Canadian veterinary journal. La revue veterinaire canadienne》2007,48(7):731-733

A 9-year-old, spayed female, Labrador retriever was referred for evaluation of dysuria. Cystoscopic examination revealed a urethral stricture in the proximal urethra that was dilated by use of an angioplasty balloon (Gruntzig angioplasty balloon) under cystoscopic guidance. Following the procedure, the dysuria resolved.  相似文献   

The Clinician Investigator program in companion animal internal medicine at north Carolina State University     

Bunch SE  Ford RB  Hawkins EC  Jackson MW  Vaden SL  Breitschwerdt EB 《Journal of veterinary medical education》2004,31(4):425-434

A retrospective study was conducted to describe the development and evolution of the combined internal medicine/PhD program, the Clinician Investigator (CI) Program, at North Carolina State University. Separate survey instruments were developed for individuals who had committed to completing both the residency and PhD components and for graduate advisors of individuals who were granted the PhD degree. Results are summarized here. Most CIs reported believing that each component of the program (clinical training and research training) provided mutual benefits and that their teaching skills were enhanced, particularly as a result of instructing students in the Veterinary Teaching Hospital. Opinions among both the CIs and the graduate advisors were divided about the benefits of a combined program compared with a sequential program; however, all but one of 11 CIs who completed the survey would enroll in the combined program again. The graduate advisors were overwhelming positive about the CIs they had advised and indicated that they would welcome a CI as a PhD student in their laboratory again. Suggested areas for improvement included guaranteed salary/stipend support for the average time to completion (six years) instead of for five years, as well as more emphasis on and guidance in identifying a graduate advisor earlier in the CI program so as to smooth the transition between the clinical and research training components of the program. It is hoped that other training programs will benefit from the summary of our experience with this program.  相似文献   

Effects of urinary tract inflammation and sample blood contamination on urine albumin and total protein concentrations in canine urine samples     

Vaden SL  Pressler BM  Lappin MR  Jensen WA 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2004,33(1):14-19

BACKGROUND: Urinary tract inflammation and hemorrhage are believed to be common causes of proteinuria in dogs based on results of studies that measured total urine protein concentration. A method to quantify urine albumin (UAlb) concentration in dogs recently has become available; however, the effect of inflammation on albuminuria is unknown. OBJECTIVES: The goals of this study were to determine the effects of urinary tract inflammation, as indicated by pyuria and sample blood contamination, on UAlb concentration and on urine protein:creatinine (UPC) ratio in dogs. METHODS: Urine samples were obtained from dogs with pyuria that were presented to a veterinary teaching hospital or were part of a laboratory colony. To mimic the effects of hematuria, canine whole blood was added to a microscopically normal canine urine sample that had baseline albumin and total protein concentrations below the limits of detection. UAlb concentration was measured using a canine albumin-specific competitive ELISA. UPC ratio was determined using routine methods. RESULTS: Of 70 samples with pyuria, 67% had negligible UAlb concentrations and 81% had normal UPC ratios. UAlb concentration but not UPC ratio was significantly higher (P < 0.05) in samples with concurrent hematuria or bacteriuria. When whole blood was added to normal urine, UAlb concentration did not exceed 1 mg/dL until the sample became visibly pink; the UPC did not exceed 0.4 at any dilution. CONCLUSIONS: Many dogs with pyuria do not have albuminuria or proteinuria; however, albuminuria may be more likely in dogs with pyuria and concurrent hematuria or bacteriuria. Hematuria may not cause an increase in UAlb concentration until it becomes macroscopic and even then may not increase the UPC ratio.  相似文献   

Feline cutaneous hemangiosarcoma: a retrospective study of 18 cases (1998-2003)     

McAbee KP  Ludwig LL  Bergman PJ  Newman SJ 《Journal of the American Animal Hospital Association》2005,41(2):110-116

Cutaneous hemangiosarcoma (HSA) has been infrequently reported in dogs and cats. Medical records of 18 cats diagnosed with cutaneous HSA were reviewed. Age at the time of diagnosis, breed, sex, tumor location, tumor size, treatment type, survival time, disease-free interval, and cause of death were evaluated. Aggressive surgical excision of the tumor was attempted in 10 cats. A complete surgical excision was achieved in five of the 10 cats. Median survival times were statistically longer in cats that underwent surgery versus cats that did not. Cats with cutaneous HSA treated with aggressive surgical excision of their tumors may have a good long-term prognosis.  相似文献