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101.
两种密度条件下玉米穗上节间距QTL分析 总被引:1,自引:1,他引:0
为研究高密度胁迫下穗上节间距的遗传机制,以豫82×沈137的重组近交系(RIL)群体为材料,构建一张包含有1 114个位点的SNP标记的遗传连锁图谱,图谱总长度为1 821.79 cM,标记平均间距为1.64 cM。利用复合区间作图法在60 000株/hm~2密度下共检测到11个、120 000株/hm~2密度下检测到12个穗上节间距的QTL,位于第6染色体上的QTLq For ILL6-2/qForILG6在两种密度下同时被检测到,表明该QTL均能稳定表达;位于第9染色体上的qThiILL9/qForILL9-1在60 000株/hm~2的密度下同时被检测到,解释穗上节间距遗传变异的8.67%和10.61%,在120 000株/hm~2密度下未被检测到,表明此QTL在低密度下特异表达调控穗上节间距3、4。在高密度下检测到qSixILG6和qSixILG10分别解释穗上节间距6遗传变异的16.97%和13.66%,说明该QTL在高密度环境下特异表达。 相似文献
102.
103.
采用水培方法,研究了不同钙离子浓度对蕹菜产量及生理生化的影响.结果表明:随着钙离子浓度的增加,蕹菜产量相应增加,当超过蕹菜生长所需的临界值时,其产量随着钙离子浓度的增加反而降低,钙离子浓度为80mg/L时,黑子蕹产量最高,达197.47 g.随着钙离子浓度的增加,3个品种蕹菜中超氧化物歧化酶活性和过氧化氢酶的活性都呈现先升高后下降的趋势,在0~80 mg/L钙离子范围内,2种酶活性随着钙离子浓度的增加而升高,在80~200 mg/L范围内,2种酶活性都随着钙离子浓度的增加而降低.相同钙离子浓度处理,3个品种中黑子蕹的净光合速率最高. 相似文献
104.
105.
Early Tumor Response to Intraarterial or Intravenous Administration of Carboplatin to Treat Naturally Occurring Lower Urinary Tract Carcinoma in Dogs 下载免费PDF全文
W.T.N. Culp C. Weisse A.C. Berent J.A. Reetz E.L. Krick D.E. Jackson P.H. Kass C.A. Clifford K.U. Sorenmo 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2015,29(3):900-907
Background
Survival times and tumor responses associated with malignant neoplasia of the lower urinary tract are poor despite the vast array of current treatments. Therefore, the evaluation of alternative treatments, such as intraarterial administration of chemotherapy (IAC) should be considered.Objective
To describe a technique for superselective catheterization for IAC and to evaluate initial tumor response by ultrasonography after both IAC and intravenous administration of chemotherapy (IVC).Animals
Client‐owned dogs with lower urinary tract neoplasia treated with either IVC (n = 15) or IAC (n = 11).Methods
Retrospective study. An arterial approach via the carotid or femoral artery was utilized to obtain superselective access and administer chemotherapy in the IAC cases. Medical record review was performed, data were recorded, and recorded variables were evaluated statistically.Results
Intraarterial chemotherapy was successfully administered in all cases. There was a significantly greater decrease in longest unidimensional measurement in the IAC group as compared to the IVC group (P = .013). The IAC group was also significantly more likely to have a tumor response as assessed by modified RECIST guidelines (P = .049). Dogs in the IAC group were significantly less likely to develop anemia (P = .001), lethargy (P = .010) and anorexia (P = .024).Conclusion and Clinical Importance
This study demonstrated the feasibility and efficacy of performing IAC for lower urinary tract neoplasia. Further investigation is necessary as the follow‐up time was short and the impact on long‐term outcome and survival was not determined. 相似文献106.
玉米秸秆热值性状杂种优势及配合力分析 总被引:3,自引:0,他引:3
采用NCⅡ交配设计以13个玉米亲本自交系组配42个杂交组合,对其玉米秸秆热值性状的杂种优势及配合力进行分析。结果表明,热值、纤维素含量、和木质素含量3个指标性状表现出明显杂种优势,热值杂种优势与纤维素含量、木质素含量的杂种优势关系密切,但不受半纤维素含量杂种优势的影响。一般配合力方差和特殊配合力方差均达到1%的极显著水平,说明不同自交系间存在较大的遗传差异。X178、掖52106的热值、纤维素含量、木质素含量的一般配合力较大,而半纤维素含量一般配合力较低;沈137的热值、木质素含量的一般配合力较高,纤维素含量的一般配合力居中,半纤维素含量的一般配合力低;这3个亲本在培育高热值玉米杂交种上具有较大应用潜力。沈137×黄C、齐319×昌7-2在热值、木质素含量、纤维素含量等性状上具有较高的特殊配合力,产生较强的杂种优势。笔者认为,玉米秸秆热值可作为玉米育种的目标之一,改变只注重产量和品质育种的做法,选育和推广既高产、优质,又高热值的玉米杂交种,提高玉米综合经济效益。 相似文献
107.
Mammary neoplasms are the most common neoplasm in female dogs. This article describes the embryologic development, normal anatomy, and histology of the canine mammary gland from the onset of first estrous and the changes that occur in the mammary gland during the estrus cycle. The clinical features of canine mammary gland tumors and their relation to prognosis are discussed, including age, hormones, breed, diet, and obesity. Additional clinical prognostic factors including clinical presentation, tumor size, and lymph node status at the time of presentation are discussed in relation to diagnosis and tumor staging. Immunohistochemical evaluation of the cell differentiation markers of the normal and neoplastic canine mammary gland is described and compared with similar studies in humans; the ways these markers may be used to assist with the prognosis of canine mammary neoplasms are discussed. 相似文献
108.
K. E. Flood‐Knapik A. C. Durham T. P. Gregor M. D. Sánchez M. E. Durney K. U. Sorenmo 《Veterinary and comparative oncology》2013,11(4):272-286
Indolent lymphoma comprises up to 29% of all canine lymphoma; however, limited information exists regarding the subtypes and biological behaviour. This retrospective study describes the clinical characteristics, histopathological and immunohistochemical features, treatment, outcome and prognostic factors for 75 dogs with indolent lymphoma. WHO histopathological classification and immunohistochemistry (IHC) for CD79a, CD3, Ki67 and P‐glycoprotein (P‐gp) was performed. The most common histopathological subtype was T‐zone, 61.7%, (MST 33.5 months), followed by marginal zone, 25%, (MST 21.2 months), P = 0.542. The addition of IHC to preliminary histopathological classification resulted in a revised diagnosis in 20.4% of cases. The use of systemic treatment did not influence survival, P = 0.065. Dogs treated with chlorambucil and prednisone did not reach a MST, compared with a MST of 21.6 months with CHOP‐based chemotherapy, P = 0.057. The overall MST of 4.4 years confirms that this is indeed an indolent disease. However, the effect of systemic treatment must be determined through prospective trials. 相似文献
109.
Karin Sorenmo 《Veterinary Clinics of North America: Small Animal Practice》2003,33(3):573-596
The National Consensus Group recommends that all women with tumors larger than 1 cm be offered chemotherapy regardless of tumor histology of lymph node status. This recommendation is to ensure that everyone at risk for failing, even though the risk may be low in women with relatively small tumors and favorable histology, has a choice and receives the benefit of adjuvant chemotherapy. This type of treatment recommendation may also be made in dogs based on recognized, well-accepted prognostic factors such as tumor size, stage, type, and histologic differentiation. Based on the limited clinical information available in veterinary medicine, the drugs that are effective in human breast cancer, such as cyclophosphamide, 5-fluorouracil, and doxorubicin, may also have a role in the treatment of malignant mammary gland tumors in dogs. Randomized prospective studies are needed, however, to evaluate the efficacy of chemotherapy in dogs with high-risk mammary gland tumors and to determine which drugs and protocols are the most efficacious. Until such studies are performed, the treatment of canine mammary gland tumors will be based on the individual oncologist's understanding of tumor biology, experience, interpretation of the available studies, and a little bit of gut-feeling. Table 2 is a proposal for treatment guidelines for malignant canine mammary gland tumors according to established prognostic factors, results from published veterinary studies, and current recommendations for breast cancer treatment in women. 相似文献
110.