THE NATURE AND CLASSIFICATION OF ANIMAL VIRUSES     

P. B. Spradbrow 《Australian veterinary journal》1964,40(5):215-219

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Sedative and cardiopulmonary effects of xylazine alone or in combination with methadone,morphine or tramadol in sheep          下载免费PDF全文

Leonardo L de Carvalho  Lilian T Nishimura  Luisa PB Borges  Sofia A Cerejo  Isadora OJ Villela  Adam Auckburally  Ewaldo de Mattos‐Junior 《Veterinary anaesthesia and analgesia》2016,43(2):179-188

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Newcastle disease virus strain I2--a prospective thermostable vaccine for use in developing countries.   总被引：6，自引：0，他引：6  

Z Bensink  P Spradbrow 《Veterinary microbiology》1999,68(1-2):131-139

Forty-five avirulent Australian strains of Newcastle disease virus had been examined for antigenicity in chickens and 18 of these were tested for thermostability. Strain I2, chosen for a combination of antigenicity and thermostability, was artificially selected for enhanced thermostability. Master seed material was then prepared in minimal disease eggs, and vaccine by a further two passages in conventional eggs. Strain I2 virus at seed and vaccine level induced adequate levels of antibody in chickens vaccinated by eye drop and usually in their contacts. The serological response to oral vaccination was less certain. Antibody titres indicative of substantial protection against virulent challenge were maintained in a simulated village flock for 38 weeks by vaccination of the foundation flock on two occasions, with subsequent vaccination confined to clutches of chicks as they were produced. Strain I2 virus survived for at least 12 weeks when stored at 22 degrees C in 1% gelatin. Strain I2 is suitable for local production of thermostable vaccine in regional laboratories in developing countries.  相似文献   

Sarcoptes scabiei infection on an alpaca (Lama pacos)     

PB McKenna  FI Hill  R Gillett 《New Zealand veterinary journal》2013,61(3)

Abstract

Extract

Sarcoptes scabiei has been reported on a number of hosts in New Zealand including the dog, ferret (Mustela putorius), pig, hedgehog (Erinaceus europaeus), llama (Lama glama) and human (Tenquist and Charleston 2001 Tenquist, JD and Charleston, WAG. 2001. A revision of the annotated checklist of ectoparasites of terrestrial mammals in New Zealand. Journal of the Royal Society of New Zealand, 31: 481–542. [Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]). We report here the first record of infestation with these mites on an alpaca (Lama pacos) in New Zealand. The mites were detected on an adult male alpaca that had been maintained for several years along with others on a property in the Wairarapa region of the North Island. The infestation manifested itself as pruritis and alopecia. On clinical examination thick, grey, hyperkeratotic crusts were visible firmly adherent to the skin of the medial surface of both hindlegs. Similar smaller and possibly more recent lesions were also evident on the animal's face, which appeared to be the only affected alpaca on the property.  相似文献   

Demodex spp. infestation and suspected demodicosis of alpacas (Vicugna pacos) in New Zealand     

FI Hill  PB McKenna  CH Mirams 《New Zealand veterinary journal》2013,61(3)

Extract

Ectoparasites known to cause skin lesions in alpacas (Vicugna pacos) include the mites Sarcoptes scabiei, Chorioptes bovis and Psoroptes spp., and the lice Microthoracius mazzai and Bovicola breviceps (Cicchino et al. 1998 Cicchino, AC, Munoz, Cobenas ME, Bulman, GM, Diaz, JC and Laos, A. 1998. Identification of Microthoracius mazzai (Phthiraptera: Anoplura) as an economically important parasite of alpacas. Journal of Medical Entomology, 35: 922–930.  [Google Scholar]; Foster et al. 2007 Foster, A, Jackson, A and D'alterio, GL. 2007. Skin diseases of South American camelids. In Practice, 29: 216–223. [Crossref], [Web of Science ®] , [Google Scholar]). Occasionally, Demodex spp. infestations have been reported or mentioned as incidental fi ndings in llamas (Lama glama) (Atlee et al. 1997 Atlee, BA, Stannard, AA, Fowler, ME, Willemse, T, Ihrke, PJ and Olivry, T. 1997. The histology of the normal llama skin. Veterinary Dermatology, 8: 165–176. [Crossref], [Web of Science ®] , [Google Scholar]) and alpacas (Foster et al. 2007 Foster, A, Jackson, A and D'alterio, GL. 2007. Skin diseases of South American camelids. In Practice, 29: 216–223. [Crossref], [Web of Science ®] , [Google Scholar]). So far, only Sarcoptes scabiei (McKenna et al. 2005 McKenna, PB, Hill, FI and Gillett, R. 2005. Sarcoptes scabiei infection on an alpaca (Lama pacos. New Zealand Veterinary Journal, 53: 213–213. [Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]), Chorioptes bovis (Arthur 1997 Arthur, DG. 1997. Diseases of lamoids in New Zealand. Surveillance, 24(1): 29–30.  [Google Scholar], non-peer reviewed) and Bovicola breviceps (Palma et al. 2006 Palma, RL, McKenna, PB and Aitken, P. 2006. Confirmation of the occurrence of the chewing louse Bovicola (Lepikentron) breviceps (Insecta: Phthiraptera: Trichodectidae) on alpacas (Lamas pacos) in New Zealand. New Zealand Veterinary Journal, 54: 253–254. [Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) have been recorded on lamoids in New Zealand. Here, we report the first record of Demodex spp. infestation of an alpaca in New Zealand.  相似文献   

Differential Rotation and Dynamics of the Solar Interior     

MJ Thompson  J Toomre  ER Anderson  HM Antia  G Berthomieu  D Burtonclay  SM Chitre  J Christensen-Dalsgaard  T Corbard  M DeRosa  CR Genovese  DO Gough  DA Haber  JW Harvey  F Hill  R Howe  SG Korzennik  AG Kosovichev  JW Leibacher  FP Pijpers  J Provost  EJ Rhodes  J Schou  T Sekii  PB Stark  PR Wilson 《Science (New York, N.Y.)》1996,272(5266):1300-1305

Splitting of the sun's global oscillation frequencies by large-scale flows can be used to investigate how rotation varies with radius and latitude within the solar interior. The nearly uninterrupted observations by the Global Oscillation Network Group (GONG) yield oscillation power spectra with high duty cycles and high signal-to-noise ratios. Frequency splittings derived from GONG observations confirm that the variation of rotation rate with latitude seen at the surface carries through much of the convection zone, at the base of which is an adjustment layer leading to latitudinally independent rotation at greater depths. A distinctive shear layer just below the surface is discernible at low to mid-latitudes.  相似文献   

Identification of Papillomaviruses in Scrapings from Bovine Warts by use of the Polymerase Chain Reaction     

Bloch  N.  Sutton  R.H.  Breen  M.  Spradbrow  P.B. 《Veterinary research communications》1997,21(1):63-68

Bloch, N., Sutton, R.H., Breen, M. and Spradbrow, P.B., 1997. Identification of papillomaviruses in scrapings from bovine warts by use of the polymerase chain reaction. Veterinary Research Communications, 21 (1), 63-68.  相似文献   

Institution, Legislation and Policy Analysis of China’s Wetland Protection     

Gerrit Hazenberg 《中国林学(英文版)》2005,(4)

Wetland protection is a complex issue. In the executive system of wetland preservation, the central government is the main body of policy formulation and implementation. Although China has taken many steps to protect wetlands, there are still some institutional, legal and policy problems in the area of wetland protection. This article presents an analysis of these factors. First, the authors state and analyze the major legal and management problems currently hampering wetland protection in China. Then the authors believe that in the future, new problems of wetland protection will arise. Given the following three major aspects of wetland protection in China: i.e., the policy, law and management systems, this article provides some relevant suggestions in the area of policies and management.  相似文献   

Some properties of lentogenic Australian newcastle disease virus     

S.J. Kim  P.B. Spradbrow 《Veterinary microbiology》1978,3(2):129-141

The Newcastle disease virus (NDV) occurring in Australia is apathogenic for chickens following natural infections. Some properties of the avirulent Australian V4 strain of NDV and of 12 new isolates of NDV were compared.The viruses grew to high titres following infection of chick embryos by the allantoic cavity and allantoic fluid had infectivity titres of from $\text{10}{}^{\mathrm{8·7}}\text{to}\text{10}{}^{\mathrm{9·5}}\text{EID}{}_{50}\text{0.2}\text{ml}$. With only two isolates did sufficient mortalities occur to allow calculation of mean death times and these were in excess of 140 h. Five of nine isolates failed to kill 100% of embryos when doses in excess of 10^7·9 EID₅₀ were used. When strain V4 was inoculated into the yolk sac of 10-day-old embryos, the LD₅₀ was similar to the ID₅₀ obtained with allantoic cavity inoculation, and the mean death time was 103 h.The intracerebral pathogenicity index for strain V4 was 0.91 and 1.02 in two experiments. The index was not significantly reduced when the virus was taken through a further cycle of plaque purification or when the inoculum was heated at 56°C for 30 min. Chickens with maternally derived antibody to NDV were not susceptible to intracerebral inoculation with strain V4. Chickens dying after intracerebral inoculation with strain V4 had haemorrhagic and necrotic liver lesions. The intracerbral pathogenicity indices for four other isolates varied from 0 to 0.22.The infectivity of V4 and three other isolates was relatively stable at 56°C and that of another eight isolates was labile. Haemagglutinins of all viruses studied were stable at 56°C for longer than 60 min. None of four isolates tested lost haemagglutinin activity on treatment with ether.Haemagglutination-elution patterns were variable but four isolates did not elute from chicken erythrocytes after 24 h at 4°C and strain V4 and isolate PM12 did not elute after 96 h at 4°C. Six viruses, including V4, agglutinated erythrocytes from all of six test horses. The haemagglutinin activity of the remaining viruses varied between horses.Four viruses including V4 haemolysed chicken erythrocytes. Gradient centrifugation allowed the separation of an infectious and a noniffectious haemagglutinin. Haemolytic activity was associated with the infectious haemagglutinin.  相似文献   

THE RESPONSE OF AUSTRALIAN CHICKENS NATURALLY INFECTED WITH AVIRULENT NEWCASTLE DISEASE VIRUS TO CHALLENGE WITH VELOGENIC NEWCASTLE DISEASE VIRUS   总被引：1，自引：0，他引：1  

P.B. Spradbrow  A. L. Ibrahim  †  Ungku  Chulan†  G. Milliken  †  R. Shapcott  † D. Kingston  † 《Australian veterinary journal》1980,56(12):580-584

SUMMARY Sixty-eight breeder chickens, 4 to 12 months of age, were taken from Australian flocks that had been naturally infected with avirulent Newcastle disease virus (NDV) and transported by air to Malaysia. Nearly all the breeders had haemagglutination inhibition antibodies to NDV, at titres of from 2 to 128. Thirty-two were inoculated intranasally with an Asian, velogenic, viscerotropic strain of NDV and all survived this challenge. Thirty-six were exposed to contact infection with the same velogenic NDV and 2 died of Newcastle disease within 14 days. The levels of haemagglutination inhibition antibodies against NDV increased in the surviving breeders after challenge, reaching 2048 or greater in a few birds. Velogenic NDV was isolated from a cloacal swab from one clinically normal breeder 10 days after challenge by contact. Cloacal swabs taken 7 to 10 days after challenge from another 23 breeders yielded no NDV. Twenty-four broilers, 7 weeks of age, were also transported from Australia to Malaysia. All lacked detectable haemagglutination inhibition antibody to NDV and they were from a flock with no detectable antibody to NDV. Twelve were challenged with velogenic NDV intranasally and 12 were subjected to contact challenge. All broilers died of Newcastle disease within 13 days.  相似文献