Relative adrenal insufficiency in dogs with sepsis     

Burkitt JM  Haskins SC  Nelson RW  Kass PH 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2007,21(2):226-231

BACKGROUND: A syndrome of relative adrenal insufficiency has been identified in septic humans, and is associated with hypotension and death. Relative adrenal insufficiency is generally associated with basal serum cortisol concentration within or above the reference range and a blunted cortisol response to adrenocorticotropic hormone administration. It is unknown whether relative adrenal insufficiency occurs in septic dogs. HYPOTHESIS: That relative adrenal insufficiency occurs in septic dogs, and that relative adrenal insufficiency is associated with hypotension and mortality. ANIMALS: Thirty-three septic dogs admitted to a small animal intensive care unit. METHODS: Dogs were included in the study if they had a known or suspected infectious disease and had systemic inflammatory response syndrome. Dogs were excluded if they had disease or medication history expected to affect the hypothalamic-pituitary-adrenal axis. Serum cortisol and endogenous plasma adrenocorticotropic hormone concentrations were measured before, and serum cortisol concentration measured 1 hour after, intramuscular administration of 250 microg of cosyntropin/dog. The change in cortisol concentration (delta-cortisol) before and after cosyntropin administration was determined in each dog. RESULTS: Hypotension was associated with lower delta-cortisol values (OR 1.3; CI 1.0-1.9; P = .029). delta-Cortisol cutoff of 3.0 microg/dL was most accurate for predicting hypotension, survival to discharge, and 28-day survival. The rate of death in dogs with delta-cortisol < or = 3 microg/dL was 4.1 times that of dogs with delta-cortisol > 3 microg/dL (RR 4.1; CI 1.5-12.3; P = .01). CONCLUSIONS AND CLINICAL RELEVANCE: Delta-cortisol < or = 3 microg/dL after adrenocorticotropic hormone administration is associated with systemic hypotension and decreased survival in septic dogs.  相似文献   

Role of the hyaluronan receptor CD44 during porcine oocyte maturation     

Yokoo M  Shimizu T  Kimura N  Tunjung WA  Matsumoto H  Abe H  Sasada H  Rodriguez-Martinez H  Sato E 《The Journal of reproduction and development》2007,53(2):263-270

Previous our studies have shown that CD44, the principal receptor for hyaluronan, is present on cumulus cells during oocyte maturation. Although hyaluronan-CD44 interaction has been implicated in cumulus expansion and/or oocyte maturation, the full significance of CD44 remains unknown. The objective of the present study was to further investigate the role of CD44 in cumulus expansion and oocyte maturation in pigs. We demonstrate here in that CD44 has a key role in oocyte maturation but not in cumulus expansion. Previous studies have reported the physiological significance of cumulus expansion in oocyte maturation. However, our results suggest that cumulus expansion is a necessary condition for oocyte maturation, but that it is not sufficient on its own. Furthermore, western blot analysis demonstrated that the CD44 of the in vitro-matured cumulus-oocyte complexes (COCs) had a larger molecular weight and more terminal sialic acid, which has been proven to inhibit the hyaluronan-binding ability of the receptor, than the CD44 of the in vivo-matured COCs, indicating that the hyaluronan-CD44 interactions during in vitro maturation might be insufficient compared with those in vivo. The insufficient interactions of hyaluronan-CD44 during in vitro maturation may cause the inferior capacity of fertilization and development of oocytes matured in vitro.  相似文献   

Chavibetol: major and potent phytotoxin in betel (Piper betle L.) leaf essential oil     

Phirose Kemprai  Pranjit Kumar Bora  Siddhartha Proteem Saikia  Saikat Haldar 《Pest management science》2023,79(11):4451-4462

  相似文献   

Potential effects of RNA interference of Asian longhorned beetle on its parasitoid     

Xingeng Wang  Jessica Faucher  Ramesh Kumar Dhandapani  Jian J. Duan  Subba Reddy Palli 《Pest management science》2023,79(4):1557-1565

  相似文献   

Evaluation of the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in critically ill dogs     

Lisa H. Dourmashkin BS  Bridget Lyons VMD  DAVCECC  Rebecka S. Hess DVM  DACVIM  Koranda Walsh VMD  DACVIM  DACVP  Deborah C. Silverstein DVM  DAVCECC 《Journal of Veterinary Emergency and Critical Care》2023,33(1):52-58

  相似文献   

Productivity impacts of the system of rice intensification (SRI): A case study in West Bengal,India     

Shekhar Kumar Sinha  Jayesh Talati 《Agricultural Water Management》2007

The system of rice intensification (SRI) has generated considerable debate globally, particularly with regard to its potential to raise rice yields. Proponents of SRI have reported that the average rice yield with SRI is double the current average yield and can be increased to the level of three to four times. Opponents say the reported high yields are due to measurement error and that usual information expected in support of these fantastic yields is missing. The number of SRI adopters has increased in India in recent years. We evaluate the impact of adoption of SRI practices on rice yields, the economics of paddy cultivation and labour inputs based on field research conducted in Purulia, West Bengal, India. Paddy yields with SRI were higher than those under conventional paddy cultivation by 32% and net returns were higher by 67%. Labour input was reduced by 8%. SRI adoption enabled farmers consistently to enhance paddy yields, increase returns and save labour; and enhance productivity with respect to the key inputs in terms of paddy output per unit of seed, fertilizer and labour-day. SRI promises to be a significant alternative for not only raising paddy yields, but also for managing paddy based farming in resource-starved regions.  相似文献   

Interactions between landscape and local factors inform spatial action planning in post-fire forest environments     

Peeler  Jamie L.  Smithwick  Erica A. H. 《Landscape Ecology》2021,36(12):3523-3537

Landscape Ecology - Landscape and local factors govern tree regeneration across heterogeneous post-fire forest environments. But their relative influence is unclear—limiting the degree that...  相似文献   

Contributing traits for nitrogen use efficiency in selected wheat genotypes and corollary between screening methodologies     

Rumesh Ranjan  Ashish Kumar  Swarupa Nanda Mandal 《Acta Agriculturae Scandinavica, Section B - Plant Soil Science》2013,63(7):588-595

ABSTRACT

Nitrogen uptake being part of nitrogen use efficiency (NUE) is largely decided by root traits. Root traits variability has hardly been explored by breeders mainly because of difficulties in scoring. The hydroponic system requiring lesser space for precise phenotyping of large numbers of genotypes independently of the growing season can be a suitable alternative. However, the effectiveness of hydroponic screening methods needs to be verified under the soil condition of the field or pot. In the present study, root traits and NUE were investigated in 19 genotypes under two conditions (hydroponic and pipe filled with soil). Both environments revealed large variability for root traits and NUE under high and low N conditions establishing the absence of any direct selection for these traits in the past. Under both sets of experimentation, NUpE was largely responsible for improved nitrogen efficiency mainly because of higher root biomass. The significant association between the two screening methods i.e. hydroponic and pot filled with soil under both low and high N condition support large scale screening for root traits under hydroponic condition.  相似文献   

Morphological variability of Atlantic salmon Salmo salar and brown trout Salmo trutta in different river environments     

Thomas J. Drinan  Phil McGinnity  Jamie P. Coughlan  Tom F. Cross  Simon S.C. Harrison 《Ecology of Freshwater Fish》2012,21(3):420-432

Abstract – The morphologies of sympatric juvenile Atlantic salmon Salmo salar parr and brown trout Salmo trutta parr were compared between Irish rivers with contrasting hydraulic environments – a high‐gradient and a low‐gradient tributary from the River Barrow catchment, south‐east Ireland and a high‐gradient river from the Burrishoole catchment, west of Ireland. The two catchments differ markedly in mean annual precipitation (849.0 mm year^?1 and 1370.3 mm year^?1 for the Barrow and Burrishoole catchments, respectively). Parr of both species demonstrated morphological variation between and within catchments. Changes in metrics such as pectoral fin length, body depth and body length between and within catchments suggest that hydraulic forces were a major determinant of morphological variation. Both species from the Burrishoole catchment had relatively larger pectoral fins, longer heads, larger eyes and shallower bodies than conspecifics from the Barrow catchment. In rivers subject to frequent rainfall‐driven high discharges, such as those in the Burrishoole catchment, a more fusiform body and head shape coupled with larger pectoral fins may reduce the energetic cost of maintaining position in the water column, as well as increase stability and manoeuvrability. The larger eyes in both parr species in the Burrishoole catchment could further be a response to the lower visibility of the more turbid and peat‐stained waters or to the reduced prey availability. The results of this study demonstrate that local adaptation to flow conditions can yield morphologically distinct populations and that multiple species can exhibit parallel phenotypic responses to changing environmental conditions.  相似文献   

Impact of Aeration on the Growth Performance of Silver Barb,Puntius gonionotus,during Fingerling Rearing     

Pratap Chandra Das  Joykrushna Jena  Bibhudatta Mishra  Bikash Kumar Pati 《Journal of the World Aquaculture Society》2012,43(1):128-134

Impact of aeration on growth of silver barb, Puntius gonionotus during fingerling rearing was studied through a 100‐d rearing experiment conducted in 18 concrete tanks of 50 m² (10 × 5 × 1.2 m) size. Fry (0.74 ± 0.27 g, 35 ± 6 mm) were stocked in the experimental tanks at three stocking densities (25, 50, and 75 fry/m²) and were evaluated with and without provision of 6 h (2400–0600 h) of night time aeration. Aeration resulted in higher pH and dissolved oxygen regime and increased fingerling length and weight. The results suggest a rearing density of 75/m² to be ideal for rearing fry to fingerling of this species when aeration is provided, whereas, under non‐aerated condition, rearing the fry to fingerling stage at 50/m² was found advantageous over those at 25 and 75/m².  相似文献