Computed tomographic assessment of vascular invasion and resectability of mediastinal masses in dogs and a cat     

WE Scherrer  AE Kyles  VF Samii  EM Hardie  PH Kass  CR Gregory 《New Zealand veterinary journal》2013,61(6):330-333

AIMS: To assess the sensitivity of non-angiographic contrast-enhanced computed tomography (CT) to determine the presence of vascular invasion of cranial mediastinal masses in dogs and a cat, and to evaluate the association between vascular invasion and peri-operative mortality.

METHODS: A retrospective study was conducted on 25 dogs and one cat. CT scans were completed with slices ranging from 2 to 10 mm. CT images were evaluated by a board-certifi ed radiologist blinded to previous diagnoses and surgical fi ndings. Each CT study was evaluated for vascular invasion, defi ned as disruption of the vessel wall and extension of the mass into the vessel lumen. Data retrieved from the surgery reports included surgical approach, whether vascular invasion was present, the surgeon's decision on operability, and post-operative complications.

RESULTS: Computed tomographic evaluation revealed 25/26 masses had no evidence of vascular invasion. During surgical exploration, 10/26 masses were found to invade major regional vasculature; the cranial vena cava (CVC) was the vessel most commonly invaded (7/10 animals), and 4/7 (57%) patients with invasion of the CVC were euthanised or died in the perioperative period, from surgical or disease-related problems, which was signifi cantly higher than patients without vascular invasion (p=0.045).

CONCLUSIONS: Non-angiographic contrast-enhanced CT was signifi cantly less sensitive for detecting vascular invasion of cranial mediastinal masses when compared with surgical evaluation. If the CVC was invaded by a tumour there was a signifi cant risk of death peri-operatively when compared with non-invasive cases.

CLINICAL RELEVANCE: Due to the signifi cantly higher mortality risk associated with invasion of the CVC, a more sensitive method than CT should be investigated to determine vascular invasion of mediastinal masses pre-operatively.  相似文献   

Germination of conidia of Aspergillus niger is accompanied by major changes in RNA profiles     

M.R. van Leeuwen  P. Krijgsheld  R. Bleichrodt  H. Menke  H. Stam  J. Stark  H.A.B. W?sten  J. Dijksterhuis 《Studies in Mycology》2013,74(1):59-70

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Comparison of Synthetic Oviductal Fluid and G1/G2 Medium under Low‐1 Oxygen Atmosphere on Embryo Production and Pregnancy Rates in Nelore (Bos indicus) Cattle     

BV Sanches  JHF Pontes  AC Basso  CR Ferreira  F Perecin  MM Seneda 《Reproduction in domestic animals》2013,48(1):e7-e9

In this work, we evaluated whether embryo development and pregnancy rates would be affected by culturing bovine Bos indicus embryos in Synthetic Oviductal Fluid with amino acids (SOFaa) or G1/G2 sequential medium under a low‐oxygen atmosphere. Using Ovum Pick Up, we obtained 1,538 oocytes, divided into G1/G2 (n = 783) and SOFaa (n = 755). No difference was observed for blastocyst development among the groups (27.8% ± 14.6 and 34.9% ± 20.0 for G1/G2 and SOFaa respectively, p > 0.05). Transferring the embryos (n = 450) from both groups to recipients resulted in similar pregnancy rates for the G1/G2 (38.4% n = 78/203) compared to the SOFaa (39.7% n = 98/247). Our findings confirm that Bos indicus embryos cultured in SOFaa and G1/G2 under low‐oxygen atmosphere have similar in vitro (blastocyst rate) and in vivo (pregnancy rate) developmental capacity. However, embryos cultured in G1/G2 medium have higher cleavage than those cultured in SOFaa medium.  相似文献   

Isolation and identification of oligomers from partial degradation of lime fruit cutin     

Tian S  Fang X  Wang W  Yu B  Cheng X  Qiu F  Mort AJ  Stark RE 《Journal of agricultural and food chemistry》2008,56(21):10318-10325

Complementary degradative treatments with low-temperature hydrofluoric acid and methanolic potassium hydroxide have been used to investigate the protective biopolymer cutin from Citrus aurantifolia (lime) fruits, augmenting prior enzymatic and chemical strategies to yield a more comprehensive view of its molecular architecture. Analysis of the resulting soluble oligomeric fragments with one- and two-dimensional NMR and MS methods identified a new dimer and three trimeric esters of primary alcohols based on 10,16-dihydroxyhexadecanoic acid and 10-oxo-16-hydroxyhexadecanoic acid units. Whereas only 10-oxo-16-hydroxyhexadecanoic acid units were found in the oligomers from hydrofluoric acid treatments, the dimer and trimer products isolated to date using diverse degradative methods included six of the seven possible stoichiometric ratios of monomer units. A novel glucoside-linked hydroxyfatty acid tetramer was also identified provisionally, suggesting that the cutin biopolymer can be bound covalently to the plant cell wall. Although the current findings suggest that the predominant molecular architecture of this protective polymer in lime fruits involves esters of primary and secondary alcohols based on long-chain hydroxyfatty acids, the possibility of additional cross-linking to enhance structural integrity is underscored by these and related findings of nonstandard cutin molecular architectures.  相似文献   

Response of bovine to immunization against Streptococcus dysgalactiae     

D M Stark  N L Norcross 《The Cornell veterinarian》1970,60(4):604-612

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Nützlinge als Bioindikatoren für die ökologischen Auswirkungen des Pflanzenschutzes in Feldstudien—Methoden und die Probleme bei der Interpretation der Daten     

B. Freier  Chr Volkmar  Th. Kreuter  H. Triltsch  A. Stark  R. Forster 《Journal of pest science》1999,72(1):5-11

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Use of Canopy Temperature Measurements as a Screening Tool for Drought Tolerance in Spring Wheat   总被引：11，自引：0，他引：11  

A. Rashid  J. C. Stark  A. Tanveer  T. Mustafa 《Journal of Agronomy and Crop Science》1999,182(4):231-238

Remotely sensed infrared canopy temperatures provide an efficient method for rapid, non-destructive monitoring of whole-plant response to water stress. Field studies were conducted in 1992 and 1993 to evaluate the potential for using canopy temperatures to screen for drought tolerance in wheat. In both years, 12 spring wheat (Triticum aestivum L.) genotypes were grown under two irrigation levels (well-watered and moisture-stressed) imposed between tillering and anthesis with a line-source sprinkler irrigation system. Canopy temperature measurements were taken in well-watered and moisture-stressed plots between 1330 and 1430 h (MDT) on five clear days in 1992 and seven clear days in 1993 during the late vegetative and early reproductive growth periods following closure of the plant canopy. Genotypes exhibited differences in mean canopy temperatures across the two irrigation levels and two years. Klasic consistently had the highest canopy temperature under moisture-stressed conditions, while Bannock and Pondera had the lowest. Bannock, Yecora Rojo and Klasic had the warmest canopies under well-watered conditions, while Vandal, Amidon and Rick had the coolest. Plot-to-plot variation in canopy temperature under water stress conditions was evident for differences in grain yield. Significant correlations between canopy temperature and yield under moisture-stress conditions and drought susceptibility index values indicated the potential for screening wheat genotypes for drought response.  相似文献   

TerraRossa: A Mid-Season Specialty Potato with Red Flesh and Skin and Resistance to Common Scab and Golden Cyst Nematode     

C. C. Shock  C. R. Brown  V. Sathuvalli  B. A. Charlton  S. Yilma  D. C. Hane  R. Quick  K. A. Rykbost  S. R. James  A. R. Mosley  E. B. G. Feibert  J. L. Whitworth  R. G. Novy  J. C. Stark  M. J. Pavek  N. R. Knowles  D. A. Navarre  J. C. MillerJr  D. G. Holm  S. S. Jayanty  J. Debons  M. I. Vales  X. Wang  L. L. Hamlin 《American Journal of Potato Research》2018,95(5):597-605

TerraRossa (POR01PG20–12) is a mid-season specialty potato, released by Oregon State University, and is a product of the Northwest Potato Variety (Tri-State) Development Program. This cultivar is unique among commercially available potato cultivars in that plants produce small- to medium-sized smooth, oblong- to long-shaped tubers with red skin and red flesh. Total tuber yields of TerraRossa are similar to Dark Red Norland and less than Red La Soda. Average tuber size (136 g) is less than both of the comparison cultivars, reflecting inherent differences in tuber size distribution. TerraRossa tubers have total antioxidant levels higher than traditional white fresh varieties and comparable to the All Blue purple potato, known for its high antioxidant levels. Sensory evaluations of TerraRossa tubers indicated that it has good culinary attributes following boiling, baking, and microwaving. Potato chips made from TerraRossa tubers retained their unique red color, which represents a novelty in the chipping industry. TerraRossa could be a good candidate for the organic sector due to its tolerance to common scab (Streptomyces scabies) and tuber late blight (Phytophthora infestans) and its resistance to golden cyst nematode (Globodera rostochiensis). Due to its high yields, high chipping quality, good culinary properties, high antioxidant content and disease resistance, TerraRossa is a good candidate for opening new specialty type markets, adding diversity to the marketplace.  相似文献   

Isolation and structure elucidation of highly antioxidative 3,8″-linked biflavanones and flavanone-C-glycosides from Garcinia buchananii bark     

Stark TD  Matsutomo T  Lösch S  Boakye PA  Balemba OB  Pasilis SP  Hofmann T 《Journal of agricultural and food chemistry》2012,60(8):2053-2062

The aim of this study was to identify antioxidants from Garcinia buchananii bark extract using hydrogen peroxide scavenging and oxygen radical absorbance capacity (ORAC) assays. LC-MS/MS analysis, 1D- and 2D-NMR, and circular dichroism (CD) spectroscopy led to the unequivocal identification of the major antioxidative molecules as a series of three 3,8″-linked biflavanones and two flavanone-C-glycosides. Besides the previously reported (2R,3R,2″R,3″R)-naringenin-C-3/C-8″ dihydroquercetin linked biflavanone (GB-2; 4) and (2R,3S,2″R,3″R)-manniflavanone (3), whose stereochemistry has been revised, the antioxidants identified for the first time in Garcinia buchananii were (2R,3R)-taxifolin-6-C-β-D-glucopyranoside (1), (2R,3R)-aromadendrin-6-C-β-D-glucopyranoside (2), and the new compound (2R,3S,2″S)-buchananiflavanone (5). The H?O? scavenging and the ORAC assays demonstrated that these natural products have an extraordinarily high antioxidative power, especially (2R,3S,2″R,3″R)-manniflavanone (3) and GB-2 (4), with EC?? values of 2.8 and 2.2 μM, respectively, and 13.73 and 12.10 μmol TE/ μmol. These findings demonstrate that G. buchananii bark extract is a rich natural source of antioxidants.  相似文献   

Intramyocardial haematoma causing right ventricular outflow obstruction after brown snake (Pseudonaja species) envenomation in a dog     

K Kang  CR Sharp  CJ Boyd  K Turner 《Australian veterinary journal》2020,98(9):455-461

A 15-month-old, male neutered Staffordshire Bull Terrier cross was presented to its referring veterinarian collapsed and agonal. He was immediately intubated, manually ventilated, and treatment commenced for presumptive snake envenomation with two vials of Tiger/Multi-Brown Snake Antivenom (minimum 7000 units/vial). The dog was transferred to a referral hospital intubated. Additional diagnostics performed following arrival at the referral hospital included a urine snake venom detection kit test, which was positive for brown snake immunotype. Three additional vials of Tiger/Multi-Brown Snake Antivenom (minimum 7000 units/vial) were administered until the dog was extubated and able to stand. Venom-induced consumptive coagulopathy (VICC) was diagnosed based on prolonged clotting times and scleral haemorrhage. Paroxysms of right ventricular outflow tract (RVOT) origin ventricular arrhythmias were treated with lignocaine and sotalol. Four days after presentation, a new-grade IV/VI systolic heart murmur was auscultated, prompting an echocardiogram. An anechoic and compartmentalised mass measuring 43 mm × 19 mm was visualized within the right ventricular wall at the RVOT, immediately adjacent to the pulmonic valve. The mass was causing a RVOT obstruction. Its appearance was suggestive of an intramyocardial haematoma, most likely secondary to VICC. The dog remained cardiovascularly stable, and treatment consisted of supportive care. Recheck echocardiograms at 2 and 7 weeks after discharge revealed progressive improvement of the intramyocardial mass and resolution of the associated heart murmur. Although intramyocardial haematomas are rare, it should be considered as a differential in dogs that develop a newly diagnosed heart murmur and/or cardiac arrhythmia following brown snake envenomation.  相似文献