Feline calicivirus     

Radford AD  Coyne KP  Dawson S  Porter CJ  Gaskell RM 《Veterinary research》2007,38(2):319-335

Feline calicivirus (FCV) is an important and highly prevalent pathogen of cats. It belongs to the family Caliciviridae which includes other significant pathogens of man and animals. As an RNA virus, high polymerase error rates convey upon FCV a high genome plasticity, and allow the virus to respond rapidly to environmental selection pressures. This makes the virus very adaptable and has important implications for clinical disease and its control. Being genetically diverse, FCV is associated with a range of clinical syndromes from inapparent infections to relatively mild oral and upper respiratory tract disease with or without acute lameness. More recently, highly virulent forms of the virus have emerged associated with a systemic infection that is frequently fatal. A proportion of FCV infected cats that recover from acute disease, remain persistently infected. In such cats, virus evolution is believed to help the virus to evade the host immune response. Such long-term carriers may only represent a minority of the feline population but are likely to be crucial to the epidemiology of the virus. Vaccination against FCV has been available for many years and has effectively reduced the incidence of clinical disease. However, the vaccines do not prevent infection and vaccinated cats can still become persistently infected. In addition, FCV strain variability means that not all strains are protected against equally. Much progress has been made in understanding the biology and pathogenesis of this important feline virus. Challenges for the future will necessarily focus on how to control the variability of this virus particularly in relation to emerging virulent strains and vaccination.  相似文献   

Feline herpesvirus     

Gaskell R  Dawson S  Radford A  Thiry E 《Veterinary research》2007,38(2):337-354

Feline herpesvirus (FHV-1; felid herpesvirus 1 (FeHV-1)) is an alphaherpesvirus of cats closely related to canine herpesvirus-1 and phocine herpesvirus-1. There is only one serotype of the virus and it is relatively homogenous genetically. FeHV-1 is an important cause of acute upper respiratory tract and ocular disease in cats. In addition, its role in more chronic ocular disease and skin lesions is increasingly being recognised. Epidemiologically, FeHV-1 behaves as a typical alphaherpesvirus whereby clinically recovered cats become latently infected carriers which undergo periodic episodes of virus reactivation, particularly after a stress. The primary site of latency is the trigeminal ganglion. Conventional inactivated and modified-live vaccines are available and protect reasonably well against disease but not infection, although viral shedding may be reduced. Genetically engineered vaccines have also been developed, both for FeHV-1 and as vector vaccines for other pathogens, but none is as yet marketed.  相似文献   

The use of intralipid emulsion therapy to treat status epilepticus in a guinea pig (Cavia porcellus) secondary to severe ivermectin toxicity     

Jennifer J. Ebel DVM  Kristi Gannon DVM  DACVECC  Mara Kraenzlin VMD  DACVECC 《Journal of Veterinary Emergency and Critical Care》2023,33(1):107-111

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Acute kidney injury from presumptive intramural ureteral hemorrhage secondary to diphacinone rodenticide exposure in a dog     

Nadene Oliver DVM  Kaila Rizzo DVM  DACVECC  Saya Press BVSc  MS  DACVECC  Stephanie Istvan VMD  DACVECC 《Journal of Veterinary Emergency and Critical Care》2023,33(1):112-117

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Evaluation of the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in critically ill dogs     

Lisa H. Dourmashkin BS  Bridget Lyons VMD  DAVCECC  Rebecka S. Hess DVM  DACVIM  Koranda Walsh VMD  DACVIM  DACVP  Deborah C. Silverstein DVM  DAVCECC 《Journal of Veterinary Emergency and Critical Care》2023,33(1):52-58

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Retrospective evaluation of factors associated with emergency frequency and survival in equids presenting for emergency care (2019–2020): 3071 cases     

Jessica Bouton DVM  Langdon Fielding DVM  DACVECC  DACVSMR  Dustin Major DVM  DACVS  Emma Deane DVM  DACVECC  Jennifer Mayer VMD  DACVECC  Diane Rhodes DVM  DACVIM 《Journal of Veterinary Emergency and Critical Care》2023,33(5):598-605

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Successful treatment of 5-fluorouracil toxicosis with hemodialysis     

Jessica S. Henry DVM  Simona Buoncompagni DVM  MS  DACVIM  Sheri Ross BSc  DVM  PhD  DACVIM  Stephanie A. Istvan VMD  DACVECC  Kaila Rizzo DVM  DACVECC  Larry D. Cowgill DVM  PhD  DACVIM  Saya A. Press BVSc  MS  DACVECC 《Journal of Veterinary Emergency and Critical Care》2023,33(3):388-392

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Intracranial medulloblastoma as the cause of progressive ataxia in a 6-month-old draft horse cross gelding     

Megan Palmisano  Susan Bender  Amy L. Johnson 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2023,37(1):361-365

We describe the unique clinical presentation of a central nervous system neoplasm in a 6-month-old draft horse cross gelding. Based on the neurologic examination at admission, neurolocalization was most consistent with a mildly asymmetric cervical, multifocal, or diffuse myelopathy. Mild vestibular involvement also was considered, but no cranial nerve deficits were observed. The gelding was negative for Sarcocystis neurona or Neospora hughesi based on paired serum and cerebrospinal fluid (CSF) samples analyzed, with no evidence of cervical compression based on contrast myelography. The horse was euthanized because of progression of clinical signs. At necropsy, a mass was identified associated with the cerebellum, and histopathology was consistent with medulloblastoma, which has not been reported previously in the horse.  相似文献   

Onchocerca sp. in an imported Zangersheide gelding causing suspensory ligament desmitis     

Kara A. Brown  Amy L. Johnson  Susan J. Bender  Thomas J. Nolan  Bianca Pfisterer  JoAnn Slack  Elinor Willis  Emily K. Rule 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2023,37(2):735-739

A 5-year-old imported Zangersheide gelding was evaluated for SC swellings over both forelimbs and lameness localized to the distal metacarpus. Ultrasound examination of the SC masses was compatible with verminous granulomas. Linear hyperechoic foci were present within the suspensory ligament branches of both forelimbs, suggestive of ligamentous parasitic infiltrates. A diagnosis of onchocerciasis was confirmed on biopsy of a SC mass. The gelding was treated with ivermectin and a tapering course of PO dexamethasone but was eventually euthanized. Necropsy confirmed the presence of SC eosinophilic granulomas and degenerative suspensory ligament desmitis, both with intralesional nematodes. Given the location and appearance of the nematode, a diagnosis of Onchocerca sp., most likely O. reticulata, was made. Onchocerciasis should be included as a differential diagnosis for multifocal suspensory ligament desmitis with these sonographic characteristics when paired with SC masses in imported European Warmbloods.  相似文献   

Crop response of drought-tolerant and conventional maize hybrids in a semiarid environment     

Ryan B. Mounce  Susan A. O’Shaughnessy  Brock C. Blaser  Paul D. Colaizzi  Steven R. Evett 《Irrigation Science》2016,34(3):231-244

In the High Plains, corn (Zea mays L.) is an important commodity for livestock feed. However, limited water resources and drought conditions continue to hinder corn production. Drought-tolerant (DT) corn hybrids could help maintain high yields under water-limited conditions, though consistent response of such hybrids is unverified. In this two-year study, the effects of three irrigation treatments were investigated for a DT and conventional maize hybrid, Pioneer AQUAMax P0876HR and Pioneer 33Y75, respectively. In 2013, the drier of the 2 years, irrigation amounts and crop water use (ET_c) were greater for the conventional hybrid, but grain water use efficiency (WUE) and harvest index were significantly greater for the DT hybrid. In 2014, grain yields and WUE were not significantly different between hybrids. However, irrigation amounts, ET_c and biomass yields were greater for the conventional hybrid. Results from both years indicate that the DT hybrid required less water to maximize grain yield as compared to the conventional hybrid. Producing relatively high yields with reduced amounts of water may provide a means for producers to continue corn production in a semiarid environment with declining water supplies.  相似文献