Effect of oral administration of electrolyte pastes on rehydration of horses     

Schott HC  Axiak SM  Woody KA  Eberhart SW 《American journal of veterinary research》2002,63(1):19-27

OBJECTIVE: To determine whether the composition of electrolyte pastes formulated for oral administration influences voluntary water intake (WI) by horses recovering from furosemide-induced dehydration. ANIMALS: 6 horses. PROCEDURES: Voluntary WI, body weight, and blood and urine constituents were measured before and after induction of dehydration by furosemide administration and overnight withholding of water; these same variables also were measured during a 36-hour rehydration period. Each horse was evaluated 4 times with random application of 4 treatments (electrolyte pastes) that provided 0.5 g of KCl/kg of body weight, 0.5 g of NaCl/kg, 0.25 g of NaCl and 0.25 g of KCl/kg, or no electrolytes (control treatment). Electrolyte pastes were administered 3 times (4, 8, and 12 hours after start of the rehydration period). RESULTS: Administration of all electrolyte pastes resulted in significantly greater voluntarily WI, compared with the control treatment, and was accompanied by significantly greater recovery of body weight when NaCl was a component of the paste. Administration of NaCl and NaCl-KCl pastes tended to produce a state of transient hyperhydration; however, electrolyte administration also resulted in significantly greater urine production and electrolyte excretion during the final 24 hours of the rehydration period. Adverse effects of oral administration of hypertonic electrolyte pastes were not observed. CONCLUSIONS AND CLINICAL RELEVANCE: Oral administration of electrolyte pastes to dehydrated horses increases voluntary WI and improves rehydration during the rehydration period. Rehydration is more rapid and complete when NaCl is a component of the electrolyte paste.  相似文献   

Serum concentrations of keratan sulfate,osteocalcin, and pyridinoline crosslinks after oral administration of glucosamine to standardbred horses during race training     

Caron JP  Peters TL  Hauptman JG  Eberhart SW  Orth MW 《American journal of veterinary research》2002,63(8):1106-1110

OBJECTIVE: To determine the effects of orally administered glucosamine on concentrations of markers of bone and cartilage metabolism in Standardbred horses during race training. ANIMALS: Twenty 16- to 20-month-old Standardbreds beginning race training. PROCEDURE: Horses were randomly assigned to 2 groups. One group received glucosamine hydrochloride (4 g, PO, q 12 h), and the second (control) group received glucose (4 g, PO, q 12 h). Serum samples were obtained prior to onset of the study (baseline) and at regular intervals for 48 weeks for determination of concentrations of keratan sulfate (KS), osteocalcin (OC), and pyridinoline crosslinks (PYD). RESULTS: Osteocalcin concentrations changed significantly with time; mean serum concentrations were significantly higher than baseline values for samples obtained at 24 to 48 weeks after onset of the study. Although a significant effect of time was observed for mean concentration of KS, concentrations did not differ significantly from baseline values at any time during the study when groups were analyzed separately. However, pooled analysis revealed significant increases of mean serum KS concentration at weeks 24 and 30. Significant changes in serum PYD concentrations were not detected. Oral administration of glucosamine did not significantly affect serum concentrations of any of the markers. CONCLUSIONS AND CLINICAL RELEVANCE: Increased serum OC in clinically normal Standardbreds during race training may reflect bone formation that accompanies adaptive remodeling of the appendicular skeleton. For these experimental conditions, glucosamine did not appear to exert a detectable influence on serum concentrations of these 3 markers of connective tissue metabolism.  相似文献   

Effects of anti-arthritis preparations on gene expression and enzyme activity of cyclooxygenase-2 in cultured equine chondrocytes     

Tung JT  Venta PJ  Eberhart SW  Yuzbasiyan-Gurkan V  Alexander L  Caron JP 《American journal of veterinary research》2002,63(8):1134-1139

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Computed tomographic osteoabsorptiometry of the elbow joint in clinically normal dogs     

Samii VF  Les Clifford M  Schulz KS  Keyak JH  Stover SM 《American journal of veterinary research》2002,63(8):1159-1166

OBJECTIVE: To evaluate subchondral bone density patterns in elbow joints of clinically normal dogs by use of computed tomographic (CT) osteoabsorptiometry. SAMPLE POPULATION: 20 cadaver forelimbs from 10 clinically normal dogs. PROCEDURE: Each elbow joint was imaged in parasagittal and transverse planes of 1.5-mm thickness. Slice data were converted to dipotassium phosphate equivalent density (PPED) values. Sagittal, parasagittal, and transverse medial coronoid process topographic maps were constructed. Defined zones were created for each of the 3 CT planes, and confluence and peak PPED values were determined. RESULTS: The lowest PPED value was 340 mg/ml (articular and subchondral confluence), and the highest was 1780 mg/ml (peak subchondral density). Detectable effects of joint laterality were not found in the confluence or peak PPED measurements or in the peak-to-confluence PPED ratio for all 3 CT planes. Significant differences were found among zones in all 3 planes for confluence and peak PPED measurements and between sagittal and transverse planes for peak-to-confluence PPED ratios. Subjectively, the pattern of density distribution among dogs was fairly consistent for the sagittal and parasagittal slices. Three specific patterns of density distribution were apparent on the transverse topographic maps of the medial coronoid process that corresponded to conformational differences. CONCLUSIONS AND CLINICAL RELEVANCE: The use of CT osteoabsorptiometry provides a repeatable technique that can be used to noninvasively examine bone density and the effects of stress acting on joints in vivo. Variability in density values for any of the CT planes was not identified among clinically normal dogs.  相似文献   

Deluge of questions prompts AAFP to develop FIV vaccine brief. American Association of Feline Practitioners     

Kahler SC;American Association of Feline Practitioners 《Journal of the American Veterinary Medical Association》2002,221(9):1231-1234

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NASA veterinarian treats Hubble Space Telescope     

Kahler SC 《Journal of the American Veterinary Medical Association》2002,221(1):18-19

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Studies offer scientific appraisal of tail docking effects in dairy cattle     

Kahler SC 《Journal of the American Veterinary Medical Association》2002,221(12):1674

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Effect of monensin on survival and growth of Escherichia coli O 157:H7 in vitro          下载免费PDF全文

Bach SJ  McAllister TA  Veira DM  Gannon VP  Holley RA 《The Canadian veterinary journal. La revue veterinaire canadienne》2002,43(9):718-719

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A bulk tank milk survey of Ostertagia ostertagi antibodies in dairy herds in Prince Edward Island and their relationship with herd management factors and milk yield          下载免费PDF全文

Sanchez J  Dohoo I 《The Canadian veterinary journal. La revue veterinaire canadienne》2002,43(6):454-459

The objective of this study was to quantify the relationship of the levels of antibodies to Ostertagia ostertagi in bulk-tank milk samples from Prince Edward Island (PEI) dairy farms to milk production and to herd-management practices potentially related to gastrointestinal nematode infections. The milk samples were obtained from 289 to 322 dairy farms during 2000; production and management data were available from 197 and 200 farms, respectively. Cow exposure to pasture and whole-herd anthelmintic treatment were the only herd management variables significantly associated with antibody levels in the fall of 2000. An increase in antibody levels from the observed 25th percentile to the 75th percentile (interquartile range) was associated with a drop in milk production of 1.2 kg/cow/day. The results of this study indicate that the enzyme-linked immunosorbent assay for O. ostertagi antibody is a potentially useful technique to measure parasite exposure in adult dairy cows and that parasite burdens in lactating cattle in PEI have an important impact on milk production.  相似文献   

Praise for the Report of the Working Group Foot and Mouth Disease but worries about high employment disabilities     

Umans S 《Tijdschrift voor diergeneeskunde》2002,127(21):658-660

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