1-O-Sulfatobastadins-1 and -2 from Ianthella basta (Pallas). Antagonists of the RyR1-FKBP12 Ca2+ Channel     

Makoto N. Masuno  Alexander C. Hoepker  Isaac N. Pessah  Tadeusz F. Molinski 《Marine drugs》2004,2(4):176-184

Two new sulfate monoesters of hemibastadins-1 and -2 were isolated from the marine sponge Ianthella basta (Pallas) from Guam. A third new compound was tentatively assigned the structure 34-O-sulfatobastadin-9. The 1-O-sulfatohemibastadins-1 and –2 were antagonists of the RyR1-FKBP12 Ca²⁺ channel under conditions where the known compound bastadin-5 exhibits potent agonism (EC₅₀ 2 μM).  相似文献   

The metal-metal interactions in biological systems Part II. Saccharomyces cerevisiae     

Bgusława Hetmańska  Piotr Tomasik  Tadeusz Tuszyński 《Water, air, and soil pollution》1994,74(3-4):281-288

The effect of eleven metal ions: Co(II), Cr(VI), Mg, Mn(II), Mo(VI), Ni(II), Pb(II), Se(IV), Ti(III), V(IV) and Zn and several combinations of them were tested for their effect on the growth of Saccharomyces cerevisiae (Mautner). The effects depended on the metal and its concentration as well as in some cases on the duration of the experiment.  相似文献   

Technogenic Magnetic Particles in Alkaline Dusts from Power and Cement Plants     

Tadeusz Magiera  Beata Gołuchowska  Mariola Jabłońska 《Water, air, and soil pollution》2013,224(1):1-17

During this study, we investigated the mineralogical characterization of technogenic magnetic particles (TMPs) contained in alkaline industrial dust and fly ash emitted by coal burning power plants and cement plants. The reaction of tested dust samples varied between values of pH 8 and pH 12. Their magnetic properties were characterized by measurement of magnetic susceptibility (χ), frequency dependence of magnetic susceptibility (χ_fd), and temperature dependence of magnetic susceptibility. Mineralogical and geochemical analyses included scanning electron microscopy with energy dispersive spectroscopy, microprobe analysis and X-ray diffraction. The TMPs in fly ash from hard coal combustion have the form of typical magnetic spherules with a smooth or corrugated surface as well as a skeletal morphology, composed of iron oxides (magnetite, maghemite, and magnesioferrite) that occurred in the form of incrustation on the surface of mullite, amorphous silica, or aluminosilicate particles. The TMPs observed in fly ash from lignite combustion have a similar morphological form but a different mineralogical composition. Instead of magnetite and magnesioferrite, maghemite and hematite with lower χ values were the prevailing magnetic minerals, which explains the much lower magnetic susceptibility of this kind of ash in comparison with the ash from hard coal combustion, and probably results from the lower temperature of lignite combustion. Morphology and mineralogical composition of TMPs in cement dust is more diverse. The magnetic fraction of cement dust occurs mostly in the form of angular and octahedral grains of a significantly finer granulation (<20 μm); however, spherules are also present. A very characteristic magnetic form for cement dust is calcium ferrite (CaFe₃O₅). The greatest impact on the magnetic susceptibility of cement dust results from iron-bearing additives (often waste materials from other branches of industry), which should be considered the most dangerous to the environment. Stoichiometric analysis of micro-particles confirmed the presence of heavy metals such as Pb, Mn, Cd, and Zn connected with TMPs, which are carriers of magnetic signals in atmospheric dust. Therefore, in some cases, their presence in topsoil when detected by magnetic measurement can be treated as an indicator of inorganic soil contamination.  相似文献   

Feline calicivirus infection. ABCD guidelines on prevention and management     

Alan D. Radford  Diane Addie  Sándor Belák  Corine Boucraut-Baralon  Herman Egberink  Tadeusz Frymus  Tim Gruffydd-Jones  Katrin Hartmann  Margaret J. Hosie  Albert Lloret  Hans Lutz  Fulvio Marsilio  Maria Grazia Pennisi  Etienne Thiry  Uwe Truyen  Marian C. Horzinek 《Journal of Feline Medicine and Surgery》2009,11(7):556-564

  相似文献   

Feline infectious peritonitis. ABCD guidelines on prevention and management     

Diane Addie  Sándor Belák  Corine Boucraut-Baralon  Herman Egberink  Tadeusz Frymus  Tim Gruffydd-Jones  Katrin Hartmann  Margaret J. Hosie  Albert Lloret  Hans Lutz  Fulvio Marsilio  Maria Grazia Pennisi  Alan D. Radford  Etienne Thiry  Uwe Truyen  Marian C. Horzinek 《Journal of Feline Medicine and Surgery》2009,11(7):594-604

  相似文献   

<Emphasis Type="Italic">Cucumber mosaic virus</Emphasis> groups IA and II are represented among isolates from naturally infected lilies     

Hanna Berniak  Maria Kamińska  Tadeusz Malinowski 《European journal of plant pathology / European Foundation for Plant Pathology》2010,127(3):305-309

Four cucumber mosaic virus isolates (named Cas, CB, P26 and Simp2) found in naturally infected lily plants were characterized on the basis of their serological properties and the results of analysis of RNA3 sequence fragments containing coat protein and movement protein genes. The properties of lily isolates were compared with those of eight other virus isolates originating from dahlia, delphinium, impatiens, honeysuckle, cucumber and redcurrant plants. On the basis of the reaction with group-specific monoclonal antibodies and RNA3 sequence analysis, two lily isolates (Cas and CB) were classified to group I of CMV, similarly to all previously reported virus isolates found in lily plants. Surprisingly, sequences of coat protein and movement protein genes of two other lily isolates (P26 and Simp2) showed more than 98% similarity to CMV group II isolates, and only 77% similarity to group I isolates. Results of ELISA with CMV group II-specific monoclonal antibodies confirmed the classification of isolate Simp2 as a member of group II. Isolate P26 reacted neither with CMV group I nor with group II-specific monoclonal antibodies. In order to explain the lack of reaction of P26 isolate with monoclonal antibodies, comparative analysis of predicted amino acid sequence of the coat protein was done. This revealed a mutation—change from alanine at position 138 to threonine, probably responsible for particular serological properties of isolate P26.  相似文献   

Effects of microcystin-containing cyanobacterial extract on hematological and biochemical parameters of common carp (Cyprinus carpio L.)     

Sieroslawska A  Rymuszka A  Velisek J  Pawlik-Skowrońska B  Svobodova Z  Skowroński T 《Fish physiology and biochemistry》2012,38(4):1159-1167

The aim of the study was to assess the effects of a cyanobacterial extract containing microcystins (MCs) on selected hematological and biochemical parameters in common carp (Cyprinus carpio L.), as well as to determine the accumulation of toxins in fish tissues. The fish were immersed for 5 days in water containing toxins at a final concentration of 12 μg/L of microcystin LR equivalent. Microcystin LR residues were detected in fish liver, reaching 207, 238 and 260 ng/g f.w. of the tissues taken 24 h, 72 h and 5 days after the end of intoxication, respectively. The most substantial changes were found in fish plasma, including increases in creatine kinase, lactate dehydrogenase, ammonia, glucose, aspartate aminotransferase and alanine aminotransferase levels. A decline of about 50% in lysozyme activity was observed by the end of the experimental period. Moreover, a marked increase in ceruloplasmin activity was detected 24 h after the end of intoxication with a subsequent decrease in its activity after 72 h and 5 days. This study concludes that not only consumption of food containing toxins but also MCs dissolved in water may pose a threat to fish health. Additionally, detected changes in lysozyme and ceruloplasmin activity may have distinct effects in fish resistance against pathogens or oxidative stress, which should be taken into account in the future studies.  相似文献   

Simultaneous selection for yield-related traits and susceptibility to Fusarium head blight in spring wheat RIL population     

Halina Wi?niewska  Maria Surma  Karolina Krystkowiak  Tadeusz Adamski  Anetta Kuczyńska  Piotr Ogrodowicz  Krzysztof Miko?ajczak  Jolanta Belter  Maciej Majka  Zygmunt Kaczmarek  Pawe? Krajewski  Aneta Sawikowska  Leszek Lenc  Anna Baturo-Cie?niewska  Aleksander ?ukanowski  Tomasz Góral  Czes?aw Sadowski 《Breeding Science》2016,66(2):281-292

Fusarium head blight (FHB), caused by the fungal plant pathogen Fusarium, is a fungal disease that occurs in wheat and can cause significant yield and grain quality losses. The present paper examines variation in the resistance of spring wheat lines derived from a cross between Zebra and Saar cultivars. Experiments covering 198 lines and parental cultivars were conducted in three years, in which inoculation with Fusarium culmorum was applied. Resistance levels were estimated by scoring disease symptoms on kernels. In spite of a similar reaction of parents to F. culmorum infection, significant differentiation between lines was found in all the analyzed traits. Seven molecular markers selected as linked to FHB resistance QTLs gave polymorphic products for Zebra and Saar: Xgwm566, Xgwm46, Xgwm389, Xgwm533, Xgwm156, Xwmc238, and Xgwm341. Markers Xgwm389 and Xgwm533 were associated with the rate of Fusarium-damaged kernels (FDK) as well as with kernel weight per spike and thousand kernel weight in control plants. Zebra allele of marker Xwmc238 increased kernel weight per spike and thousand kernel weight both in control and infected plants, whereas Zebra allele of marker Xgwm566 reduced the percentage of FDK and simultaneously reduced the thousand kernel weight in control and infected plants.  相似文献   

Retained Fetal Membranes in Heavy Draft Mares Associated with Histological Abnormalities     

Anna Rapacz  Katarzyna Pa?dzior  Andrzej Ra?  Tadeusz Rotkiewicz  Tomasz E. Janowski 《Journal of Equine Veterinary Science》2012,32(1):38-44

Retention of fetal membranes is one of the most common life-threatening peripartum problems; however, its etiology is still unknown. Draft mares are more likely to retain fetal membranes than other breeds of mares. Because a strong connection between the fetal membranes and the endometrium has been observed in cases of retention, we studied the changes in the endometrium and the allantochorion of heavy draft mares with this condition. Tissue samples were taken from 90 mares that retained the fetal membranes and from 21 that did not. Retained fetal membranes were associated with adhesion of the allantochorion to the endometrium in 88% of the mares; this adhesion depended on the following factors: occurrence of fibrosis both in the lamina propria of the allantochorial villi and in the allantochorial stromal connective tissue, overdevelopment of the allantochorial stromal connective tissue, oversized allantochorial epithelial cells, and sparser and less-branched allantochorial villi.  相似文献   

Quaternary ammonium salts and arginine are inhibitors of general amino acid permease in yeast     

Tadeusz M. Lachowicz  Jerzy Piatkowski  Stanislaw Witek 《Pest management science》1995,43(2):169-171

  相似文献