Effects of experimentally induced Isospora suis infection on morbidity, mortality, and weight gains in nursing pigs   总被引：1，自引：0，他引：1  

D S Lindsay  W L Current  J R Taylor 《American journal of veterinary research》1985,46(7):1511-1512

Forty-nine pigs from 6 litters were inoculated at 3 days of age with 300,000 sporulated oocysts of Isospora suis to determine the effects of neonatal coccidiosis on morbidity, mortality, and weight gain in nursing pigs. Fifty-one control pigs from 6 litters were not inoculated. Three to 5 days after inoculation, the inoculated pigs developed a nonhemorrhagic diarrhea, generally lasting 6 to 10 days, that lead to visible dehydration, loss of condition, and 20.4% mortality. Control pigs did not die or develop coccidiosis during the 3-week study and had significantly (P less than 0.05) greater body weights at 7, 14, and 21 days of age than did the inoculated pigs.  相似文献   

Future of veterinary education.     

W R Ward  P H Holmes  D Taylor 《The Veterinary record》1992,131(4):82-83

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Cryptosporidiosis associated with immunosuppression attributable to distemper in a pup     

G H Turnwald  O Barta  H W Taylor  J Kreeger  S U Coleman  S S Pourciau 《Journal of the American Veterinary Medical Association》1988,192(1):79-81

Cryptosporidiosis, giardiasis, trichomoniasis, and distemper were diagnosed in a 6-month-old female Siberian Husky pup. Poor growth rate, mucopurulent ocular and nasal discharges, and diarrhea were observed. Results of immunologic studies revealed decreased serum IgG concentration and undetectable serum IgA concentration. Cultured lymphocytes yielded a less-than-adequate response to mitogen stimulation. The serum also contained a factor that suppressed mitogen stimulation in control cultured lymphocytes.  相似文献   

Characterization of Newcastle disease virus (avian paramyxovirus-1) isolated from pigeons   总被引：2，自引：0，他引：2  

J E Pearson  D A Senne  D J Alexander  W D Taylor  L A Peterson  P H Russell 《Avian diseases》1987,31(1):105-111

Newcastle disease virus (avian paramyxovirus-1) was isolated from pigeons in 12 states between May 1984 and December 1985. One of the isolates was from a feral pigeon; the remainder were from privately owned pigeon lofts. Use of monoclonal antibodies showed seven of the eight isolates tested to be indistinguishable from the 1982 and 1983 Great Britain and European isolates. Clinical signs were paralysis, torticollis, tremors, incoordination, and death. Pigeons inoculated with the paramyxovirus-1 isolates intravenously or intramuscularly developed clinical disease identical to that described for natural infection; however, only one pigeon inoculated intranasally developed clinical signs. The mean death time for inoculated pigeons was 9.5 days, with a range of 4 to 25. Virus was shed for up to 20 days. Primary lesions observed on necropsy were gastroenterocolitis and pancreatic necrosis. Chickens experimentally infected by the cloacal, intranasal, or caudal thoracic air-sac route remained healthy. However, the intracerebral pathogenicity index (ICPI) in day-old chickens was similar to that observed with velogenic Newcastle disease virus isolates. Four of six isolates inoculated intravenously into 6-week-old chickens induced neurotropic disease.  相似文献   

Nonsecretory Multiple Myeloma in a Dog: Immunohistologic and Ultrastructural Observations     

Stanley L. Marks  Peter F. Moore  Debra W. Taylor  Robert J. Munn 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1995,9(1):50-54

A 12-year-old, female spayed Chihuahua was diagnosed with nonsecretory multiple myeloma on the basis of multiple osteolytic lesions, histological evidence of plasma cell infiltrate on a bone biopsy, and absence of a monoclonal protein on serum and urine electrophoresis. A 6-week course of prednisone therapy resulted in no clinical improvement and the dog was euthanized 2 weeks after presentation because of progressive neurological impairment. Bone marrow specimens were processed and stained for ultrastructural and immunohistologic evaluation. Staining with antisera to immunoglobulin (Ig) G, IgM, and IgA was negative. Tumor cells in both the pelvic and rib masses displayed prominent reactivity with an antibody specific for a canine β1 integrin similar to VLA-4; however, the tumor cells failed to stain with antibodies known to react predominantly with antigens on B-lymphocytes (major histocompatibility complex class II, CD45RA, and CD21) or T-lymphocytes (Thy-1). The tumor cells also failed to stain with an antibody specific for the β-subunit (CD18) of the leukocyte integrins (CD11/CD18). Ultrastructural studies performed on bone marrow specimens revealed a pleomorphic population of plasma cells with moderate amounts of rough endoplasmic reticulum, erythrophagocytosis, and lack of crystalline inclusions.  相似文献   

Plasma cell pododermatitis with chronic footpad hemorrhage in two cats     

J E Taylor  L P Schmeitzel 《Journal of the American Veterinary Medical Association》1990,197(3):375-377

Plasma cell pododermatitis was diagnosed in 2 cats with enlargement of the metacarpal and metatarsal footpads, ulceration of one of the affected footpads, and a history of chronic hemorrhage from the ulcerations. One cat was anemic (PCV, 14.6%). The ulcers were debrided and sutured to control hemorrhage, and the cats were treated with immunosuppressive doses of corticosteroids. Both cats had considerable reduction in footpad size after 3 to 4 weeks of treatment. Although there is evidence to suggest that plasma cell pododermatitis might be immune-mediated, or perhaps an allergic disease, the cause has yet to be determined.  相似文献   

Acute oxalate poisoning attributable to ingestion of curly dock (Rumex crispus) in sheep     

R J Panciera  T Martin  G E Burrows  D S Taylor  L E Rice 《Journal of the American Veterinary Medical Association》1990,196(12):1981-1984

Ten of 100 mature ewes were afflicted with acute oxalate toxicosis within 40 hours after being temporarily penned in a lot that contained considerable growing Rumex crispus (curly dock). Clinical signs of toxicosis included excess salivation, tremors, ataxia, and recumbency. Affected ewes were markedly hypocalcemic and azotemic. Oxalate crystals were not observed in urine. Gross postmortem lesions were minimal and nondiagnostic in 2 ewes that died peracutely, but perirenal edema and renal tubular degeneration were clearly observable in ewes euthanatized on the third day of toxicosis. Diagnosis of oxalate toxicosis was confirmed by histopathologic findings. Samples of Rumex spp contained 6.6 to 11.1% oxalic acid on a dry-weight basis, a concentration comparable with that in other oxalate-containing plants that have caused acute oxalate toxicosis.  相似文献   

The present state of national animal welfare policy     

MA O'FLYNN  JD O'DEA 《Australian veterinary journal》1996,73(4):121-124

Animal welfare is expected to increase in importance as a political and marketing issue. There is a vigorous debate about what, besides the absence of physical pain, is necessary for acceptable animal welfare. This paper focuses on the present state of animal welfare policy at the national level.  相似文献   

LHRH and beta-endorphin in the hypothalamus of the ram in relation to photoperiod and reproductive activity     

F J Ebling  G A Lincoln  G B Martin  P L Taylor 《Domestic animal endocrinology》1987,4(3):149-156

The regional distribution and relative concentrations of LHRH and beta-endorphin immunoreactivity in the hypothalamus were compared in sexually active and sexually inactive Soay rams. LHRH was localized principally in the medial basal hypothalamus and median eminence with lower concentrations in the anterior hypothalamus and preoptic area. beta-endorphin immunoreactivity was also found in highest concentrations in these regions but was more widely distributed into the rostral, dorsal and lateral parts of the hypothalamus. LHRH content in the medial basal hypothalamus was significantly lower in the sexually active rams compared to inactive rams while there was no difference in beta-endorphin immunoreactivity content between the two groups. Gel filtration chromatography of hypothalamic extracts revealed that the beta-endorphin immunoreactivity was due to both beta-lipotropin and beta-endorphin; the ratio of beta-endorphin: beta-lipotropin tended to be less in the sexually active rams than in the sexually inactive rams. The results are consistent with the hypothesis that beta-endorphin is a physiologically important endogenous opioid involved in the modulation of LHRH secretion.  相似文献   

Continuing presence of rinderpest virus as a threat in East Africa, 1983-1985     

P B Rossiter  W P Taylor  B Bwangamoi  A R Ngereza  P D Moorhouse  J M Haresnape  J S Wafula  J F Nyange  I D Gumm 《The Veterinary record》1987,120(3):59-62

The re-emergence of rinderpest virus in East Africa in 1979 caused widespread outbreaks of disease and subclinical infection throughout the region until mid-1983. Subsequent massive emergency vaccination campaigns have been successful in eliminating clinical rinderpest from Tanzania and preventing its spread southwards. Unfortunately the virus is still endemic in north-eastern Uganda and has recently caused epidemic outbreaks with high mortality in cattle in that country. In Kenya, buffaloes (Syncerus caffer) in and around the Masai Mara game reserve have developed antibodies to rinderpest virus as recently as late 1984. Although there have been no outbreaks of clinical disease in Tanzania or Kenya from April 1983 to the end of 1985 this serological evidence plus the increasing incidence of clinical outbreaks in Uganda indicate that rinderpest virus still threatens East Africa. The substantial aid which has been provided to the region for rinderpest control must be maintained.  相似文献