Abrupt climate events 500,000 to 340,000 years ago: evidence from subpolar north atlantic sediments     

DW Oppo  JF McManus  JL Cullen 《Science (New York, N.Y.)》1998,279(5355):1335-1338

Subpolar North Atlantic proxy records document millennial-scale climate variations 500,000 to 340,000 years ago. The cycles have an approximately constant pacing that is similar to that documented for the last glacial cycle. These findings suggest that such climate variations are inherent to the late Pleistocene, regardless of glacial state. Sea surface temperature during the warm peak of Marine Isotope Stage 11 (MIS 11) varied by 0.5 degrees to 1 degrees C, less than the 4 degrees to 4.5 degrees C estimated during times of ice growth and the 3 degrees C estimated for glacial maxima. Coherent deep ocean circulation changes were associated with glacial oscillations in sea surface temperature.  相似文献   

Lectin Histochemistry as a Tool to Identify Apoptotic Cells in the Seminiferous Epithelium of Syrian Hamster (Mesocricetus auratus) Subjected to Short Photoperiod     

V Seco‐Rovira  E Beltrán‐Frutos  C Ferrer  MM Sánchez‐Huertas  JF Madrid  FJ Saez  LM Pastor 《Reproduction in domestic animals》2013,48(6):974-983

Lectins have been widely used to study the pattern of cellular glycoconjugates in numerous species. In the process of cellular apoptosis, it has been observed that changes occur in the membrane sugar sequences of these apoptotic cells. The aim of our work was to identify which lectins, out of an extensive battery of the same (PNA, SBA, HPA, LTA, Con‐A, UEA‐I, WGA, DBA, MAA, GNA, AAA, SNA), show affinity for germinal cells in apoptosis, at what stage of cell death they do so and in which germinal cell types they can be detected. For this, we studied testis sections during testicular regression in Syrian hamster (Mesocricetus auratus) subjected to short photoperiod. Several lectins showed an affinity for the glycoconjugate residues of germ cells in apoptosis: Gal β1,3‐GalNAcα1, α‐d ‐mannose, N‐acetylgalactosamine and l ‐fucose. Furthermore, lectin specificity was observed for some specific germinal cells and in certain stages of apoptosis. It was also observed that one of these lectins (PNA) showed affinity for Sertoli cells undergoing apoptosis. Therefore, we conclude that the use of lectin histochemistry could be a very useful tool for studying apoptosis in the seminiferous epithelium because of the specificity shown towards germinal cells in pathological or experimentally induced epithelial depletion models.  相似文献   

Fatal, congenitally acquired infection with equine arteritis virus in a neonatal thoroughbred.     

W E Vaala  A N Hamir  E J Dubovi  P J Timoney  B Ruiz 《Equine veterinary journal》1992,24(2):155-158

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Thoracic haemangiosarcoma in a 3-year-old horse     

JF FREESTONE  MM WILLIAMS  G NORWOOD 《Australian veterinary journal》1990,67(7):269-270

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Salmonella serotypes from animals in New York State, 1978-1983   总被引：3，自引：0，他引：3  

P L McDonough  S J Shin  J F Timoney 《The Cornell veterinarian》1986,76(1):30-37

The salmonella serotypes isolated during 1978 to 1983 at the diagnostic and clinical laboratories of the New York State College of Veterinary Medicine from animal sources in New York state were reviewed and compared to earlier data from New York state animals and to national data for both human and animal sources. A total of 255 salmonella strains were studied from the six year period and included 33 serotypes. Salmonella enteritidis ser Typhimurium continued to be the most commonly reported serotype followed by serotype Anatum. Generally serotypes from New York state animals reflected national data on salmonella serotypes with a few exceptions. Serotype Dublin continued to be absent from New York animal populations. Bovine and equine species were the most common salmonella sources.  相似文献   

Endocrine Regulation of Reproductive Function in Fertile, Subfertile and Infertile Stallions     

JF Roser 《Reproduction in domestic animals》1995,30(4):245-250

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Salmonella give infection in cattle     

J Timoney 《The Veterinary record》1970,86(17):520-521

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Hormonal Regulation of the Oestrous Cycle of Cattle     

JF Roche  E Austin  M Ryan  M O'Rourke  M Mihm  M Diskin 《Reproduction in domestic animals》1998,33(3-4):227-231

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Histology and ultrastructure of the equine lingual tonsil. II. Lymphoid tissue and associated high endothelial venules     

Kumar P  Timoney JF 《Anatomia, histologia, embryologia》2005,34(2):98-104

The stratified squamous epithelium of the lingual tonsil of five young horses was infiltrated with CD4 and CD8 positive cells, which were very numerous in the crypt reticular epithelium along with macrophages and IgGb and IgA positive cells. Lymphoid follicles of the lamina propria mucosae consisted of a parafollicular area, corona and germinal centre. The parafollicular area was populated by large numbers of CD4 and CD8 positive lymphocytes as well as macrophages, inter-digitating cells, and a few B-lymphocytes. The germinal centre contained mainly IgGb and IgG(T) positive cells, plasma cells and small numbers of follicular dendritic cells, macrophages, CD4, CD8 and IgA positive cells. Some venules in the parafollicular and inter-follicular areas had features characteristic of high endothelial venules with irregular nuclei and cytoplasmic processes on the luminal surface. In addition to the normal cytoplasmic organelles, a novel vesiculo-vacuolar organelle was observed in small clusters toward the lateral, luminal and abluminal surfaces of these high endothelial venules. These vesiculo organelles along with their stomata and diaphragms, communicated with each other and with inter-endothelial clefts forming a structural basis for enhanced permeability and extravasation of macromolecules. The presence of lymphocytes in the high endothelial venules is consistent with transmural and inter-endothelial passage of these cells.  相似文献   

Histology, immunohistochemistry and ultrastructure of the equine tubal tonsil   总被引：1，自引：0，他引：1  

Kumar P  Timoney JF 《Anatomia, histologia, embryologia》2005,34(3):141-148

The tubal tonsil of the horse surrounds the pharyngeal opening of the eustachian tube and is lined by pseudostratified columnar ciliated epithelium interspersed with areas of follicle-associated epithelium (FAE) heavily infiltrated by lymphocytes but devoid of goblet and ciliated cells. Scanning and transmission electron microscopy revealed microvillous cells and cells with features characteristic of M cells such as reduced microvilli or depressed bare surface, more numerous mitochondria, small vesicles and lysosomes, as well as vimentin filaments and epitopes specific for GS 1-B4 as previously seen in the nasopharyngeal tonsil. M cells were also identified in areas of respiratory epithelium not associated with lymphoid follicles and appeared to be the nasal mucosal counterparts of recently described intestinal villous M cells in the mouse. The underlying lymphoid tissue of the FAE was generally organized as solitary lymphoid follicles without germinal centres in contrast to the diffuse and large amount of organized lymphoid follicles with germinal centres that characterize the nasopharyngeal tonsil. CD8+ T and B-lymphocytes were much fewer than in the nasopharyngeal tonsil. High endothelial venules were mainly oriented towards the parafollicular area and contained much fewer endothelial pores and vesiculo-vacuolar organelles. Finally, scattered small clusters of mucus acini and striated muscles were other features that differentiated the tubal and nasopharyngeal tonsils.  相似文献