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A recent shortage of prepackaged heparinized saline (HS) syringes has led to the question of whether or not normal saline (NS) can be used to both flush and lock IV catheters in large animal medicine (LAM). Moreover, several known medication incompatibilities exist with IV heparin administration. This is of particular concern in veterinary medicine where limited to no compatibility data exists between “veterinary only” (non-Food and Drug Administration approved) medications and heparin. Most of the literature on this subject is in human medicine where flushing of peripheral IV lines (PIVL) is done safely and effectively with NS. The jugular lines inserted in LAM have characteristics that are more similar to PIVLs versus most central venous access devices used in human patients. In addition, LAM catheters are of larger diameter than those typically used in human medicine thereby reducing the risk of occlusion. Based on the data evaluated, flushing and locking all LAM catheters with of NS is a reasonable alternative method for maintaining IV patency and eliminating problems associated with medication-related incompatibilities or shortages of prepackaged HS syringes. 相似文献
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Kivell TL Kibii JM Churchill SE Schmid P Berger LR 《Science (New York, N.Y.)》2011,333(6048):1411-1417
Hand bones from a single individual with a clear taxonomic affiliation are scarce in the hominin fossil record, which has hampered understanding the evolution of manipulative abilities in hominins. Here we describe and analyze a nearly complete wrist and hand of an adult female [Malapa Hominin 2 (MH2)] Australopithecus sediba from Malapa, South Africa (1.977 million years ago). The hand presents a suite of Australopithecus-like features, such as a strong flexor apparatus associated with arboreal locomotion, and Homo-like features, such as a long thumb and short fingers associated with precision gripping and possibly stone tool production. Comparisons to other fossil hominins suggest that there were at least two distinct hand morphotypes around the Plio-Pleistocene transition. The MH2 fossils suggest that Au. sediba may represent a basal condition associated with early stone tool use and production. 相似文献
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Continuous flow vapor generation for inductively coupled argon plasma spectrometric analysis. Part 1: Selenium 总被引:6,自引:0,他引:6
Total selenium is determined by inductively coupled plasma (ICP) atomic emission using hydride vapor generation. A 1 g sample is wet ashed in a 16 x 150 mm 10 mL volumetric test tube on a programmed heating block with nitric, sulfuric, and perchloric acids at up to 310 degrees C. After treatment with hydrochloric acid, the selenium is reduced by sodium borohydride to hydrogen selenide is a simplified continuous flow manifold. A standard pneumatic nebulizer effects the gas-liquid separation of H2Se, which is quantified by ICP atomic emission at 196.090 nm. The instrument detection limit for the method has been determined to be 0.4 microgram/L. For a 10:1 dilution of a nominal 1 g sample, the detection limit is 4 micrograms/kg and the linear range is up to 4 mg/kg. The method has demonstrated statistical control for samples of biological and environmental interest and is especially well suited to analysis of small samples. 相似文献
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Jeffrey A. Wilcox Patrick L. Tracy Nancy H. Marcus 《Journal of the World Aquaculture Society》2006,37(1):113-120
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In vivo andin vitro techniques were used to examine the influence of various vertebrate peptides on growth hormone (GH) secretion in the goldfish.
Tetradecapeptide somatostatin (SRIF-14) was found to inhibit GH secretionin vitro from perifused pituitary fragments, whereas similar concentrations of a salmonid SRIF peptide (sSRIF-25) did not affect GH
secretion from the goldfish pituitary fragments. This indicates that SRIF receptors on the goldfish pituitary are very specific
for SRIF-14-like peptides. Salmon gonadotropin (GTH)-releasing hormone (sGnRH) was found to elevate serum GH levels in male
goldfish. The dopamine antagonist pimozide alone or injected in combination with sGnRH did not influence serum GH levels,
although injection of pimozide alone significantly elevated serum GTH levels, in addition to potentiating the effects of sGnRH
on GTH secretion. sGnRH stimulated GH secretion from goldfish pituitary fragmentsin vitro, indicating that sGnRH acts directly at the level of the pituitary to stimulate GH secretion in the goldfish. These results
suggest that GnRH may also function as a GH-releasing factor in the goldfish, although the release-inhibitory factors for
GH and GTH secretion do appear to be separate and distinct. Two human GH-releasing hormone (hGHRH) peptides were found to
be ineffective in altering GH secretionin vitro from the perifused pituitary fragments. Consequently, a role for a mammalian GHRH-like peptide in the hypothalamic regulation
of GH secretion in the goldfish remains questionable. 相似文献