Peroxidative protection of parenteral admixture by D-alpha-tocopherol     

Becvarova I  Saker KE  Swecker WS  Troy GC 《Veterinary therapeutics : research in applied veterinary medicine》2005,6(4):280-290

High lipid:low dextrose (HL:LD) parenteral admixtures (PAs) are becoming commonplace in the nutritional support of veterinary patients. Lipid peroxidation before administration appears to be an unwanted sequela of high lipid content in PAs that can lead to oxidative injury of biologic membranes in vivo. The purpose of this in vitro study was to measure hydroperoxides in HL:LD PAs and to determine the optimal dose of d-alpha-tocopherol to minimize peroxidation in these PAs during a 24-hr period. Detectable concentrations of hydroperoxides were present in all PAs. D-alpha-tocopherol appeared to significantly minimize peroxidation of HL:LD PAs in vitro. These results have clinical implications for parenteral feeding in critically ill patients.  相似文献   

Failure of Technetium Tc 99m sestamibi scanning to detect abnormal parathyroid tissue in a horse and a mule with primary hyperparathyroidism     

Wong D  Sponseller B  Miles K  Butt T  Kersh K  Myers R 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2004,18(4):589-593

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Mass envenomation of a mare and foal by bees     

N Lewis  DJ Racklyeft 《Australian veterinary journal》2014,92(5):141-148

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Characterization of the North American beaver (Castor canadensis) papillomavirus genome     

Artem S. Rogovskyy  Zigui Chen  Robert D. Burk  Troy Bankhead 《Veterinary microbiology》2014

The papillomaviruses comprise a large group of viruses that cause proliferations of the stratified squamous epithelium of skin and mucosa in a variety of animals. An earlier report identified a novel papillomavirus of the North American beaver, Castor canadensis (CcanPV1) that was associated with cutaneous exophytic lesions. In the current study, we determined the sequence of the complete 7435 basepair genome of CcanPV1. The genome contains an Upstream Regulatory Region located between the end of L1 and the start of E6, and seven canonical papillomavirus open reading frames encoding five early (E6, E7, E1, E2, and E4) and two late (L2 and L1) proteins. No E5 open reading frame was detected. Phylogenetic analysis of the CcanPV1 genome places the virus between the genera Kappapapillomavirus and Mupapillomavirus. Analyses of the papillomavirus genomes detected in different species of the order Rodentia indicate these viruses do not form a monophyletic clade.  相似文献   

A "Schrodinger Cat" Superposition State of an Atom   总被引：1，自引：0，他引：1  

C Monroe  DM Meekhof  BE King  DJ Wineland 《Science (New York, N.Y.)》1996,272(5265):1131-1136

A "Schrodinger cat"-like state of matter was generated at the single atom level. A trapped 9Be+ ion was laser-cooled to the zero-point energy and then prepared in a superposition of spatially separated coherent harmonic oscillator states. This state was created by application of a sequence of laser pulses, which entangles internal (electronic) and external (motional) states of the ion. The Schrodinger cat superposition was verified by detection of the quantum mechanical interference between the localized wave packets. This mesoscopic system may provide insight into the fuzzy boundary between the classical and quantum worlds by allowing controlled studies of quantum measurement and quantum decoherence.  相似文献   

High-quality binary protein interaction map of the yeast interactome network   总被引：1，自引：0，他引：1  

Yu H  Braun P  Yildirim MA  Lemmens I  Venkatesan K  Sahalie J  Hirozane-Kishikawa T  Gebreab F  Li N  Simonis N  Hao T  Rual JF  Dricot A  Vazquez A  Murray RR  Simon C  Tardivo L  Tam S  Svrzikapa N  Fan C  de Smet AS  Motyl A  Hudson ME  Park J  Xin X  Cusick ME  Moore T  Boone C  Snyder M  Roth FP  Barabási AL  Tavernier J  Hill DE  Vidal M 《Science (New York, N.Y.)》2008,322(5898):104-110

Current yeast interactome network maps contain several hundred molecular complexes with limited and somewhat controversial representation of direct binary interactions. We carried out a comparative quality assessment of current yeast interactome data sets, demonstrating that high-throughput yeast two-hybrid (Y2H) screening provides high-quality binary interaction information. Because a large fraction of the yeast binary interactome remains to be mapped, we developed an empirically controlled mapping framework to produce a "second-generation" high-quality, high-throughput Y2H data set covering approximately 20% of all yeast binary interactions. Both Y2H and affinity purification followed by mass spectrometry (AP/MS) data are of equally high quality but of a fundamentally different and complementary nature, resulting in networks with different topological and biological properties. Compared to co-complex interactome models, this binary map is enriched for transient signaling interactions and intercomplex connections with a highly significant clustering between essential proteins. Rather than correlating with essentiality, protein connectivity correlates with genetic pleiotropy.  相似文献   

Investigation of Johne's disease in Tasmanian fallow deer (Dama dama)     

RB Jackson  DJ Kennedy  ESG Sergeant 《Australian veterinary journal》2021,99(1-2):44-45

In 2012 when many sheep flocks in northern‐central Tasmania were experiencing a high prevalence of ovine Johne's disease, 34 wild adult fallow deer shot on or near infected properties were negative to microscopic Mptb lesions of the ileo‐caecal valve, terminal ileum and ileo‐caecal lymph nodes. This study demonstrated 95% confidence of detecting Johne's disease in this fallow deer population if ≥10% of animals were shedding Mycobacterium avium subsp. paratuberculosis in their faeces, or if ≥21% of animals were sub‐clinically infected.  相似文献   

Factors associated with survival and racing performance of 114 Thoroughbred foals with septic arthritis compared with maternal siblings (2009-2015)     

Thomas J. O’Brien  Sarah M. Rosanowski  Keith D. Mitchell  Joan B. Carrick  Troy D. Butt  Angus R. Adkins 《Equine veterinary journal》2021,53(5):935-943

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Elemental concentrations in fresh snowfall across a regional transect in the northeastern U.S.: Apparent sources and contribution to acidity     

W. Troy Baisden  Joel D. Bluh  Eric K. Miller  Andrew J. Friedland 《Water, air, and soil pollution》1995,84(3-4):269-286

Fresh snowfall was collected on the surface of 8 lakes across a 350 km west-east transect from northeastern New York state to the coast of Maine after a single storm. In addition, every snowfall event during the winter of 1993 was collected on a single lake near the center of the transect. Across the transect, midwestern sources appear to dominate Pb and Cd concentrations, while Sb appears to be derived from midwestern sources as well as local and/or industrial East Coast sources. In all samples, the highest Na, Cl and Mg concentrations reflect a marine influence, but at some transect sites roadspray aerosol appears to contribute to Na and Cl concentrations. The regional pattern of Ca, K, Mn and Sr concentrations and Mn/Sr ratios indicate that woodsmoke may be an important winter source of these elements at some sites. In all samples, H⁺ is strongly correlated with NO₃ ^? (R² = 0.97) and mean NO₃ ^?/SO₄ ^2? molar ratios of 6.4 for transect samples, and 4.7 for temporal samples, are higher than mean NO₃ ^?/SO₄ ^2? reported for other precipitation studies in the same region. The contribution of NO₃ ^? to the snowpack greatly exceeds that of SO₄ ^2?, and may be a major source of acidity in aquatic ecosystems during snowmelt.  相似文献   

Retrospective analysis of 736 cases of canine gastric dilatation volvulus     

KK Song  SE Goldsmid  J Lee  DJ Simpson 《Australian veterinary journal》2020,98(6):232-238

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