Association between anesthesia duration and outcome in dogs with surgically treated acute severe spinal cord injury caused by thoracolumbar intervertebral disk herniation     

Joe Fenn  Hongyu Ru  Nick D. Jeffery  Sarah Moore  Andrea Tipold  Franz J. Soebbeler  Adriano Wang-Leandro  Christopher L. Mariani  Peter J. Early  Karen R. Muñana  Natasha J. Olby 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2020,34(4):1507-1513

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Socio-economic, dietary, activity, nutrition and body weight transitions in South Korea     

Lee SK  Sobal J 《Public health nutrition》2003,6(7):665-674

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Effect of feeding a high-protein diet following an 18-hour period of feed withholding on mammalian target of rapamycin-dependent signaling in skeletal muscle of mature horses     

Urschel KL  Escobar J  McCutcheon LJ  Geor RJ 《American journal of veterinary research》2011,72(2):248-255

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Asparaginase-associated pancreatitis in a dog     

Schleis SE  Rizzo SA  Phillips JC  LeBlanc AK 《The Canadian veterinary journal. La revue veterinaire canadienne》2011,52(9):1009-1012

A dog with lymphosarcoma was evaluated for vomiting, lethargy, and abdominal pain 48 h after treatment with L-asparaginase. Based on drug administration, clinical signs, bloodwork, and elevated canine pancreatic lipase immunoreactivity, L-asparaginase-associated pancreatitis was diagnosed. This is an acknowledged toxicity; however, its pathophysiology and incidence rate in veterinary patients are unknown and sparsely documented.  相似文献   

Intrathecal deep digital flexor tenectomy for treatment of septic tendonitis/tenosynovitis in four horses     

Marsh CA  Watkins JP  Schneider RK 《Veterinary surgery : VS》2011,40(3):284-290

Objective: To describe partial removal of the intrathecal component of the deep digital flexor tendon (DDFT) in horses with chronic septic DDF tendonitis and tenosynovitis unresponsive to conventional therapy, and to report long‐term outcome. Study Design: Case series. Animals: Horses (n=4). Methods: Four horses with chronic septic DDF tendonitis and tenosynovitis were treated by surgical tenectomy of the intrathecal component of the DDFT, followed by stabilization in casts and subsequent corrective shoeing. All horses were previously managed unsuccessfully with combinations of conventional therapy consisting of systemic antibiotics, through and through tendon sheath lavage/open drainage, regional limb perfusions, tenoscopy with debridement and transection of the palmar/plantar annular ligament, and intrathecal antibiotics. Results: Time from initial injury/diagnosis to tenectomy ranged from 10 to 210 days. Mean hospitalization time after surgery was 82 days. Long‐term follow‐up (>1.5 years; mean, 3.8 years) was available. All 4 horses were able to walk comfortably at pasture and were used as broodmares. Conclusions: Intrathecal tenectomy is a viable surgical procedure for treatment of chronic septic tenosynovitis of the digital sheath that is complicated by septic tendonitis of the DDFT.  相似文献   

Brain abscess in a dog immunosuppressed using cyclosporin     

Smith PM  Haughland SP  Jeffery ND 《Veterinary journal (London, England : 1997)》2007,173(3):675-678

This report describes a dog that developed brain abscesses following prolonged immunosuppression with cyclosporin. Bacteria within the abscess were most likely Nocardia, an organism well recognised in immunosuppressed humans, and probably reached the brain through haematogenous spread from a more long-standing abscess in the mediastinum. Bacterial brain abscesses developing in this manner are very rare in dogs and this case highlights the wider range of possible diagnoses that need to be considered in immunosuppressed patients and the care with which potent drugs such as cyclosporin should be used.  相似文献   

Fractures of the greater tubercle of the humerus in horses: 15 cases (1986-2004)     

Mez JC  Dabareiner RM  Cole RC  Watkins JP 《Journal of the American Veterinary Medical Association》2007,230(9):1350-1355

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Preliminary studies on the effectiveness of the novel pulicide, spinosad, for the treatment and control of fleas on dogs     

Snyder DE  Meyer J  Zimmermann AG  Qiao M  Gissendanner SJ  Cruthers LR  Slone RL  Young DR 《Veterinary parasitology》2007,150(4):345-351

Spinosad is a novel mode-of-action insecticide produced from a family of natural products derived from fermentation of the actinomycete, Saccharopolyspora spinosa. Separate studies were undertaken to determine the minimum effective dose of spinosad given orally for the treatment of experimentally induced flea infestations (Ctenocephalides felis) on dogs, and to assess any potential impacts of feeding canned or dry food at the time of dosing. Both were randomized block (blocked by gender and pre-treatment flea counts), blinded parallel-arm studies, with dogs selected on health and ability to maintain pre-treatment flea populations. For dose selection, 48 dogs were allocated among six groups (8 dogs/group; 4 males, 4 females): placebo-treated negative control, spinosad in gelatin capsules at 15, 20, 30 and 40 mg/kg administered per os; and topical imidacloprid (10 mg/kg) as a positive control. Placebo and spinosad treatments were administered on Days 0, 30 and 60, imidacloprid only on Day 0. In a second study to assess the impact of food type at the time of dosing, three groups were formed: placebo-treated control (8 dogs; 4 males, 4 females), spinosad (30 mg/kg) administered with canned food (8 male dogs, 8 females); and spinosad (30 mg/kg) with dry food (8 males, 8 females). Treatments were administered on Days 0 and 30. To assess post-treatment persistent efficacy, flea infestations were repeated at regular post-treatment intervals, beginning on Day 5 through Day 89 in the dose selection study and Day 58 in the impact of food type and dosing study. Flea counts were performed 48 h post-infestation by study personnel who were blinded to treatments. In the dose selection study, compared to geometric mean live flea counts in the control group, each spinosad dose was highly effective (99.8–100%) at 7, 14 and 21 days after treatment. Only the 30 and 40 mg/kg doses maintained high efficacy (97.2–100%) until 30 days after treatment, with no difference between the two. Imidacloprid was highly effective at Day 30, with significant difference only from the 15 mg/kg spinosad group. Because there was no significant difference between the higher spinosad rates, 30 mg/kg was selected as the optimal minimum effective dose. In the second study, spinosad was highly effective at all post-treatment flea counts (98–100%). Taken together, these studies demonstrate that repeated monthly oral treatments with spinosad at 30 mg/kg provide sustained control of C. felis on dogs. There were no treatment-related adverse events in either study, indicating that spinosad has potential to be used monthly as a safe and effective flea adulticide, providing sustained activity that matches that of currently used topical products.  相似文献   

Changes          下载免费PDF全文

Nick Jeffery 《The Journal of small animal practice》2015,56(6):359-359

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Scaling the CRAG to smooth the path to publication in JSAP          下载免费PDF全文

Nick Jeffery 《The Journal of small animal practice》2015,56(7):423-424

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