SINGLE‐SHOT TURBO SPIN ECHO PULSE SEQUENCE FINDINGS IN DOGS WITH AND WITHOUT PROGRESSIVE MYELOMALACIA          下载免费PDF全文

Lindsey J. Gilmour  Nick D. Jeffery  Kristina Miles  Elizabeth Riedesel 《Veterinary radiology & ultrasound》2017,58(2):197-205

Progressive myelomalacia is an uncommon type of ischemic, hemorrhagic spinal cord infarction. Diagnosis can be difficult, but prompt recognition is important. We hypothesized that cerebrospinal fluid signal attenuation on magnetic resonance (MR) images would be more extensive in dogs that developed progressive myelomalacia vs. control dogs. A retrospective analytic cohort study was designed. Dogs were included if they presented for acute paraplegia and loss of deep pain perception and had undergone MR imaging using both sagittal single‐shot turbo spin echo (SSTSE) and standard sagittal T2‐weighted fast spin echo (T2W) pulse sequences. Dogs were divided into progressive myelomalacia and control groups for comparisons. All MR examinations were evaluated by three reviewers blinded to patient outcome. Length of cerebrospinal fluid attenuation was recorded as a ratio to the length of the L2 vertebral body in SSTSE and T2W sequences (CSF:L2_SSTSE and CSF:L2_T2, respectively). Length of intramedullary spinal cord hyperintensity was recorded as a ratio to the length of the L2 vertebral body in T2W sequences. A total of 21 dogs were included (five in the progressive myelomalacia group and 16 in the control group). The mean CSF:L2_SSTSE attenuation value was significantly higher in dogs that developed progressive myelomalacia (CSF:L2_SSTSE = 10.7) compared to controls (CSF:L2_SSTSE = 5.4; P = 0.015). A cut off ratio of attenuation >7.4 provided optimal differentiation between groups in this study. Findings supported the conclusion that dogs with CSF:L2_SSTSE ≤ 7.4 are unlikely to develop progressive myelomalacia while dogs with CSF:L2_SSTSE > 7.4 are indeterminate for progressive myelomalacia.  相似文献   

Urban environment: a risk factor for canine immune‐mediated disease?          下载免费PDF全文

U. Jeffery 《The Journal of small animal practice》2017,58(11):639-644

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Intranasal Midazolam versus Rectal Diazepam for the Management of Canine Status Epilepticus: A Multicenter Randomized Parallel‐Group Clinical Trial          下载免费PDF全文

M. Charalambous  S.F.M. Bhatti  L. Van Ham  S. Platt  N.D. Jeffery  A. Tipold  J. Siedenburg  H.A. Volk  D. Hasegawa  A. Gallucci  G. Gandini  M. Musteata  E. Ives  A.E. Vanhaesebrouck 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2017,31(4):1149-1158

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