Extraction of adrenal cortex hormone activity from placental tissue     

JOHNSON RH  HAINES WJ 《Science (New York, N.Y.)》1952,116(3017):456-457

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Probabilistic Models Applied to Hospital Planning     

DAVID E. AULT  THOMAS E. JOHNSON 《Growth and change》1973,4(2):7-13

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Histological Appearance of Naturally Occurring Canine Physeal Fractures     

JANNA M. JOHNSON dvm    ANN L. JOHNSON DVM  MS  JO ANN C. EURELL dvm  PhD 《Veterinary surgery : VS》1994,23(2):81-86

The Salter-Harris classification system is widely used to describe the anatomical appearance of and predict the prognosis for physeal fractures in canine clinical patients. Salter and Harris classified experimentally induced physeal fractures on radiographic and histological appearance, however, the good prognosis afforded Salter-Harris type I and II fractures in experimental animals has been questioned for the canine patient. Twelve naturally occurring physeal fractures from five traumatized dogs, who were euthanatized at the request of their owners, and one resected femoral head were examined histologically. Ten of the 13 physeal fractures disrupted the cells in the proliferative zone. The histological appearance of growth plate disruption in the injured animal correlates more closely with the clinical observations of growth retardation than the experimental observation of continued growth after fracture through the hypertrophic zone. The results of this study indicated that considerable damage to the physeal cartilage occurred during the traumatic incident in most of these clinical animal patients.  相似文献   

AN EVALUATION OF THE AUSTRALIAN BEEF CARCASE APPRAISAL SYSTEM     

E. R. JOHNSON  D. D. CHARLES 《Australian veterinary journal》1976,52(4):149-154

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Thrombin-E as a fibrinolytic enzyme     

SEEGERS WH  LANDABURU RH  JOHNSON JF 《Science (New York, N.Y.)》1960,131(3402):726

Thrombin-E has been produced in adequate quantity for pharmacological studies. After intravenous infusion in dogs there were no significantchanges in blood pressure, temperature, pulse rate, and respiratory movements. There were drops in platelet and white cell count, and there was an increase in bloodsugar level. Powerful fibrinolytic phenomena wereobserved.  相似文献   

A case of intestinal impaction in a Marginated Tortoise (Testudo marginata)     

M. PAYNE JOHNSON 《The Journal of small animal practice》1984,25(7):453-456

A case of impaction of the large intestine in the Marginated Tortoise (Testudo marginata) is described. It was associated with the ingestion of pebbles, probably in an attempt to obtain calcium.  相似文献   

OBSERVATIONS ON THE EPIDEMIOLOGY OF PORCINE PARVOVIRUS   总被引：3，自引：0，他引：3  

R. H. JOHNSON B.V.SC  M.R.C.V.S.  Ph.D.  Dip. Bact  M.R.C. Path.    C. DONALDSON-WOOD B.V.SC.  B.Sc.    HAN Soo JOD D.V.M.  U. ALLENDER B.Agr.Sc. 《Australian veterinary journal》1976,52(2):80-84

Evidence presented suggests that porcine parvovirus is highly stable and infective. Introduction of virus to susceptible herds results in 100% infection rate within the following 3 months. Active immunity is associated with high persistent levels of haemagglutination-inhibitating (HI) antibody (> 256), piglets suckling immune sows acquiring HI titres between 10,000 and 40,000. Loss of passive immunity, measured by HI, occurs in a majority of pigs between 14 and 26 weeks of age (mean 21 weeks), whilst an average of 25% (2–47%) of pigs lose HI titres between 26 and 36 weeks of age. Susceptibility to challenge with virus does not occur until 3–5 weeks following loss of HI titres. In endemically infected herds 98–100% of adult pigs show serological evidence of active immunity.
A significant proportion of gilts may not be actively immune to porcine parvovirus at the time of first service, and subsequent infection may occur while these gilts are pregnant.  相似文献   

Pasteurella multocida septicaemia in two calves     

BD HILL  RB JOHNSON 《Australian veterinary journal》1992,69(8):197-198

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Comparison of efficacy of several delivery methods using Yersinia ruckeri bacterin on rainbow trout, Salmo gairdneri Richardson   总被引：1，自引：0，他引：1  

K. A. JOHNSON  D. F. AMEND 《Journal of fish diseases》1983,6(4):331-336

Abstract. The comparative efficacy of several methods of vaccinating rainbow trout, Salmo gairdneri Richardson, with Yersinia ruckeri bacterins was evaluated. In general, the protective immunity was best by intraperitoneal injection followed by direct immersion, shower and spray, respectively. The bacterin was effective by all methods when diluted 1:20 or less, but there was a trend towards less efficacy with higher dilutions and shorter exposure time.  相似文献   

The influence of cimetidine on the pharmacokinetics of the enantiomers of verapamil in the dog during multiple oral dosing     

L.M. JOHNSON  S.M. LANKFORD  S.A. BAI 《Journal of veterinary pharmacology and therapeutics》1995,18(2):117-123

The disposition of intravenously (0.5 mg/kg) and orally (5 mg/kg) administered verapamil was studied in six dogs after 3 days' pre-treatment with verapamil alone (5 mg/kg, every 8 h) and during concomitant oral administration of cimetidine (16 mg/kg, every 8 h). Racemic verapamil and norverapamil, an active metabolite of verapamil, were measured by fluorescence high performance liquid chromatography using an achiral phenyl column. The isolated racemic verapamil was rechromatographed on an Ultron-OVM chiral column, which separated the two verapamil enantiomers. Cimetidine co-administration significantly reduced the systemic clearance of racemic verapamil as well as that of its enantiomers by 25–29%. The clearance of racemic verapamil administered orally as well as that of its enantiomers was also reduced by 28% during cimetidine coadministration. The decrease in verapamil metabolism by cimetidine appeared to be non-stereoselective. On the other hand, cimetidine co-administration had no significant effect on the apparent volume of distribution of racemic verapamil and its enantiomers or the plasma protein binding or the blood to plasma concentration ratio of racemic verapamil. In addition, the ratio of the area under the plasma concentration-time curve for norverapamil to that of verapamil was unaffected by cimetidine co-administration. These results suggest that cimetidine alters the disposition of verapamil by decreasing the hepatic blood flow rate and by inhibition of its first-pass metabolism.  相似文献